UPD

COMMITTED TO RAISING AWARENESS AND FUNDS TO AID IN THE ERADICATION OF BREAST CANCER

Volume 10 . Issue 21 . Winter 2008-09

UPDATE is published annually by EXPEDITION INSPIRATION . 501 (c) (3) #91-1646381

251 S. Main . Suite 200 . Box 4289 . Ketchum, Idaho 83340 . Tel 208 726-6456 . Fax 208 725-2091 . Email ei@expeditioninspiration.org

www.expeditioninspiration.org

DEAR FRIENDS,

Greetings rom the Expedition In-spiration Medical Advisory Board(MAB)! As we come to the end o aremarkable year, it is with great plea-sure and a sense o excitement and ac-complishment that I take this oppor-tunity to update you on the scienticactivities o EI over the past year. Itis a great privilege to work with my distinguished colleagues on the MABto implement EI’s vision to advancebreast cancer treatment throughscientic exchange, public educationand support o the next generation o breast cancer researchers.Te

welth

Annual Laura Evans Memorial Breast Cancer Symposium

, which took place March 5 – 9, 2008, was truly an outstanding event. EI’s distinguished

Scientifc Advisor, Dr. Marc Lippman,

assembled an internationally recognized group o investigators who are changing the aceo breast cancer treatment, and will no doubt be leaders inimproving breast cancer outcomes in the years ahead. Tepresentations highlighted important work advancing theability to tailor new breast cancer therapies to the speciceatures o both the host and the tumor, leading to a“personalized” approach to treatment that will maximizebenet and minimize side eects. I have no doubt that suchadvances will revolutionize how we care or women withbreast cancer within the next decade.MAB members also participated in two public orums,aimed at helping patients, amilies and health care providersgain knowledge o the latest breast cancer treatments. Te

Public Forum

in Sun Valley, which took place during theSymposium, brought together MAB members and invitedscientists in a panel discussion that ocused on the latestin treatment, side eects, risk assessment and prevention.Later in the year, MAB members

Dr. Michael Press, Dr.Ronald Dorn, Dr. Robert Vestal

and I joined with expertsrom the

Mountain States umor Institute(MSI)

at the

Tird Annual

Boise PublicForum

, where we reviewed the latest researchrom both the American Society o ClinicalOncology and San Antonio Breast CancerSymposia. Both o these events gave the MABa wonderul opportunity to educate ourcolleagues, patients and amilies about breastcancer advances and how they may aecttheir treatment and outcome in the uture.Finally, this year we had the opportunity to support outstanding scientists whorepresent the next generation o breastcancer researchers through

ExpeditionInspiration Young Investigator Awards

. It was indeed challenging to choose just twooutstanding junior scientists or these awardsrom among a strong group o applicants who will undoubtedly contribute valuable knowledge to the eld.

Dr. Elizabeth Iorns,

rom the University o Miami School o Medicine, received an awardto support her work identiying the unique genetic eatures o tumorstem cells, a specialized type o breast cancer cell that is thought tobe resistant to chemotherapy and radiation and may be responsibleor the ability o tumors to recur and travel to other parts o the body.

Dr. Jineng Suo

, rom the Baylor School o Medicine, received anaward to support her work in understanding the role o the

Int-6

gene in directing production o critically important proteins aectingbreast cancer growth.Te generous support o our donors has enabled EI to have a real andlasting impact on breast cancer research, education and training. Inthe challenging current economic times, EI plays an ever increasingrole in lling the gap let by decreased ederal research unding. We

thank you or your enduring support

o Laura Evans’ vision,helping to make such tremendous progress possible! Angela DeMichele, MD, MSCE

Dr. Angela DeMichele

YOUR DONATIONS AT WORK

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Your donations truly make a difference to people battling Breast Cancer. Currently, in additionto the Annual Laura Evans Memorial Breast Cancer Symposium, Expedition Inspiration is fundingseveral important studies. Read about the research your generous gifts are supporting.

12TH ANNUAL LAURA EVANSMEMORIAL BREAST CANCERSYMPOSIUM2008

op breast cancer researchers rom aroundthe globe attended EI’s Symposium, titled,“

New Terapeutic Approaches to Breast Cancer.”

Te world-renowned meeting was again chaired by Expedition InspirationScientic Advisor,

Marc Lippman, MD

,one o the world’s leading authorities in theeld o breast cancer.Expedition Inspiration was pleased toinclude the two recipients o its 2007 YoungInvestigator Award grants.

Vijayakirishna Gadi, MD, PhD

University o Washingtonand

N. Lynn Henry, MD, Phd

University o Michigan were invited to presenttheir research studies to the Symposiumparticipants. It was an invaluable experienceor all the Symposium participants. A very special thank you to

Bristol-Myers Squibb

, which underwrote theSymposium.

OPEN FORUM2008

Expedition Inspiration hosted the ree community

Open Forum,

held inconjunction with its welth Annual Laura Evans Memorial Breast CancerSymposium entitled,

“New Terapeutic Approaches to Breast Cancer.”

Featured speakers or the 2008 Open Forum were

Daniel F. Hayes, MD

,Clinical Director o the Breast Oncology Program at the University o MichiganComprehensive Cancer Center and

C. Kent Osborne, MD,

Director o the BaylorCancer Center and Breast Center, and Proessor o Medicine and Cellular &Structural Biology at the Baylor College o Medicine. Te Open Forum also eatured

“Meet Te Experts

” and a

“Question and Answer”

Session, where community attendees were invited to ask specic questions o these renowned medical experts.Te Open Forum continues to be a wonderul opportunity to learn rom the top inthe world!Tank you to the

St. Luke’s Wood River Foundation

or generously underwritingthe 2008 Open Forum

YOUNG INVESTIGATOR AWARDS2008

Your generous donations have enabled us to und two Young Investigators in 2008.Te Medical Advisory Board was again pleased with the number o applicants orthe two grants available in 2008. Tis year the seven member committee determinedthat

Elizabeth Iorns, MD

rom the University o Miami Leonard M. Miller Schoolo Medicine and

Jineng Suo, PhD

rom Baylor College o Medicine were the two Young Investigator Grant recipients.Expedition Inspiration Young Investigator Grants are made possible – again thanksto our generous donors – and come at a critical time in the development o theircareers as clinical breast cancer scientists and junior aculty members.

2www.epeditioninspiration.org

2008 Open Forum, Sun Valley, Idaho

BOISE PUBLIC FORUM2008

Expedition Inspiration presented the Tird Annual Boise Public Forumon June 11, 2008. EI Medical Advisory Board Members

Dr. Angela DeMichele

, Assistant Proessor o Medicine and Epidemiology, Abramson Cancer Center at the University o Pennsylvania and

Dr. Michael Press

, Harold E. Lee Chair, Proessor o Pathology,Keck School o Medicine, Norris Comprehensive Cancer Center atthe University o Southern Caliornia were eatured speakers. Tey presented medical ndings rom the recent American Society o ClinicalOncology (ASCO) meeting. Specialists rom St. Luke’s MountainStates umor Institute participated in a Question and Answer Sessionand Panel Discussion. A huge thank you to

St. Luke’s MountainStates umor Institute

and

St. Luke’s Breast Care Services

orgenerously underwriting this event.

THIRTEENTH ANNUAL SYMPOSIUM2009

Expedition Inspiration will host the Tirteenth AnnualLaura Evans Memorial Breast Cancer Symposium inSun Valley, Idaho, February 25 - March 1, 2009. Breastcancer research scientists rom around the world willattend the symposium titled,

“Using Bioinormaticso ransorm

Breast Cancer.”

Te world-renownedmeeting will again be chaired by Expedition InspirationScientic Advisor,

Marc Lippman, MD

. Your continued unding o Expedition Inspirationprograms enables our organization to continue to hostthis highly respected meeting. Tank you.

www.epeditioninspiration.org3

SAVE THE DATEOpen Forum Thursday, February 26, 2009

Expedition Inspiration invites you to our

Open Forum

on Tursday, February 26 rom 5-7 p.m., at the SunValley Inn Limelight Room. Tis Open Forum, held inconjunction with

“Using Bioinormatics o ransorm

Breast Cancer”

is oered ree to the community.Symposium participants will present inormationon the latest advancements in breast cancer researchtopics, such as: targeted treatments, clinical trials, newadvances, alternative therapies, estrogen replacementand preventative measures. Tere will be a Questionand Answer Session, which provides patients, amilies,medical proessionals and members o the press theopportunity to ask questions o these world-renownedresearchers.

Everyone is invited to attend.

ExpeditionInspiration’s 2009 Open Forum is generously sponsoredonce again by a grant rom the

St. Luke’s Wood RiverFoundation.

Tank you to the Foundation or thisincredible support.

FOURTH ANNUAL TWILIGHT SNOWSHOECELEBRATION PLANNED2009

Plans are under way or the

Fourth Annual wilight Snowshoe Celebration

to be held at the elegant ElkhornSprings Restaurant. We have added a amily snowshoe during the day and aSweetheart Bar or ater hours to ensure that there is “somethingor every Valentine.”Funds raised during these events will be used to support promisingyoung researchers in the eld o breast cancer and help und the13th Annual Laura Evans Memorial Breast Cancer Symposium.ickets or the wilight Snowshoe Celebration are $125, and arecurrently on sale. ickets or the amily oriented “Heart o theFamily Snowshoe” will be available at a later date.

WELCOME NEW BOARD OF DIRECTOR

JOHN A. LUNG, MD.

EI is thrilled to welcome

Dr. John Lung

to the Board o Directors.Dr. Lung was raised in Oklahoma, and he received undergraduateeducation at Oklahoma State University and attended medical schoolat the University o Oklahoma. Dr. Lung moved his amily to Boise, Idaho in 1972 and in 1982 he was appointed director o the Breast Cancer Detection Center andsurgical consultant at the Mountain States umor Institute. He is amember o several proessional organizations including: Te WesternSurgical Association, Society o Surgical Oncology and the AmericanSociety o Breast Disease.Dr. Lung met EI ounder Laura Evans when he participated in therst Annual Symposium. He was impressed by Evans’ unique ability to motivate and engender enthusiasm in the pursuit o a cure orbreast cancer.

Tat continues to remain the goal o ExpeditionInspiration today.

RESERVE YOUR TICkETS NOW FOR THIS FUN EVENT! FEBRUARY 14, 2009

2008 Moonlight Snowshoe