Committed to raising awareness and funds to aid in the eradication of breast cancer

2001 has been a challenging and incredibly exciting year for theresearch programs of the Expedition Inspiration Fund for Breast Cancer Research. In this issue of the newsletter you will find thebreast cancer research grants approved by the EIFBCR Medical Board, including the annual Collaborative and Young Researcher Grants awarded from our Symposium.This year, the 5th Annual EIFBCR Symposium addressed thecomplex issue of

“Hormones in the Etiology, Prognosis,Prevention and Treatment of Breast Cancer.”

Our annualSymposium continues to grow in success and influence in thebreast cancer research community. Also in this issue of the newsletter you will find a short summary of the highlightsf rom this year’s “Consensus and Action Items” statement tobe published in the journal

“Breast Cancer Research andTreatment”

—a statement meant to provide new ideasand research directions to the breast cancer research community. The Consensus Statement from the 2000 Symposium was published earlier this year in the sameprestigious journal under the editorial direction of Dr. Marc Lippman.Finally, I am extremely pleased to announce that EIFBCR Medical Board member

Dr. Julie Gralow

f romthe University of Washington in Seattle has agreed toassume the duties of Chairman of the Medical Board.Dr. Gralow’s acknowledged expertise in the field of breast cancer research and treatment will bring a new level of recognition and validation to the activities of the Fund. I look forward to working with Dr. Gralowin the coming years, continuing our fight againstbreast cancer.

Message

f rom the

Medical Board

Ronald V. Dorn III, MD

New Medical Board Chair

Julie Gralow, MD, Assistant Pro f es so r, Dept. of Medicine, Division of Oncology at the University of Washington School of Medicine, Seattle, Washington has beennamed as Chairman of the Medical Board.“Dr. Gralow has been on our medical boardfor three years.” Said Katie Powell,Executive Director of EI, “and we are hon-ored that she has stepped up as the chair.Her reputation as a clinical researcher in the field of breast cancer can only further our organization’s goal—which is to find a cure for this disease.”

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U PD ATE is published two times a year by EXPEDITION INSPIRATION 640 North Main . Box 4289 . Ketchum, Idaho 83340 . Tel 208 726-6456 . Fax 208 725-2091 . E Mail ei@expeditioninspiration.org

w w w. e x e d i t i o n i n s i r a t i o n . o r

Mt. Whitney 2001

“The First Annual Michele Ann Potkin MemorialClimb” up Mt. Whitney was held in late August. Ourteam summitted to a beautiful sunrise on August 30. Theclimb was dedicated to honor Michele, who climbedwith EI founder, Laura Evans. Michele perished in anavalanche in 2000. Her dear friend, Diane Warren, underwrote this climb as a fitting tribute to Michele, her love of climbing, and her commitment to the breast cancer cause. Many thanks to Diane Warren and

TheDiane Warren Foundation

for their support of EI.Check out their website at: www. di a n e w a rre n f ou n d a-t i o n @ realsongs.com. Next year’s “Second AnnualMichele Ann Potkin Memorial Climb”, up Mt. Whitneyis scheduled for August 17-23, 2002. See our 2002Passport in this issue for more information.

Expedition Inspiration tribute flags are proudly flown fromthe summit of Mt. Whitney(14,497’) at sunrise on August 30. Julie Houk, of Mountain Home, ID and Laurie Barrera, EI Board Member and breast cancersurvivor, Boise, ID, celebrate with their guides from Sierra Moutaineering.

Paul Delorey,

a member of the “original” ExpeditionInspiration Fund team, is retiring as President of JanSport in December of this year. Not only was Delorey on the Aconcagua summit team, he was instrumental in the financial success of the event, as J a n S p o rt was the underwriter of the climb inArgentina. Mt. Aconcagua, at 22,841’ is the highestmountain in the western hemisphere. In 1995 LauraEvans and Peter Whittaker lead a team of 17 breast cancer survivors to face the second greatest challengeof their lives. This wasmadepossible by the support of Paul Delorey and the entire JanSportteam. JanSportha scontinued to supportExpedition Inspirationin the years since. Wewish Paul the best inhis retirement—though we know Paul won’t beidle! Thank you andgood luck!

Research Funding

As a result of the 2001 Symposium and to encouragecollaboration, the Expedition Inspiration MedicalBoard has awarded the following grants:

A $15,000 Collaborative Grant

has been made to

Drs. Kathleen Grant,

Calif ornia Pacific Medical Center and

Stefanie Jeffrey

of Stanford Universityfor their work on “Comparison of Molecular Markers(Steroid Receptors) in Asian and Caucasian Breast Cancer Patients.”

A $20,000 Outstanding Young Researc h e rAward

has been make to

Lisa Newman,

MD for theKarmanos Cancer Institute for her work—“Feasibilityof Evaluating Breast Cancer Patients with NippleAspirates and Ductal Lavage.”Funds for these grants were raised at the 2000 PinnaclePicnic held in Sun Valley, Idaho. Thank you to all who attended and donated to the picnic and auction.

A complete list of grants is available on our website.

The Fifth AnnualExpedition InspirationMedical Symposium

“Hormones in the Etiology, Prognosis, Prevention and Treatment of Breast Cancer”

held in March in Sun Valley, Idaho, brought together seventeen researchers from around the country. They spent two intensive days discussing this aspect of breast cancer. The formatof the Symposium was an interactive workshop to encouragediscussions of the general issues of breast cancer, with special empha-sis on this year’s subject.Several important conclusions were reached, resulting in a consensusstatement which suggests promising avenues for future research. Highlights of this consensus statement, to be published in a forth-coming issue of

“Breast Cancer Research and Treatment,”

include:

Estrogen-receptor positive (ER+)

breast cancers are more responsive to hormone therapy. There are at least two distinct forms of ER+receptors; further work in characterizing these forms should result inmore effective use of hormone therapy.

Prevention of breast cancer by alteration of the timing of hormonalexposure during a woman’s lifetime

(beginning before birth), or bydietary means, is an area of great potential but in need of far more studies.Please see the complete summary statement on our website

www.expeditioninspiration.org.

PARTICIPANTS INCLUDED

Samuel Hellman, MD, University of Chicago; Ronald V. Dorn, MD,Mountain States Tumor Institute; Marc Lippman, MD, University of Michigan; William Hryniuk, MD,Karmanos Cancer Institute; Gini F. Fleming, MD, University of Chicago Medical Center; Julie Gralow,MD, University of Washington Medical Center; Geoffrey Greene, MD, University of Chicago; RobertHoover, MD, National Cancer Institute; Stefanie Jeff rey, MD, Stanford University; Malcolm Pike, PhD, USC Keck School of Medicine; Christopher Benz, MD, University of California, San Francisco; MalcolmMitchell, MD, Karmanos Cancer Institute; Leena Hilakivi-Clark, Georgetown University MedicalCenter; Suzanne Conzen, MD, University of Chicago Medical Center; Craig Henderson, MD, ALZA;Kathleen Grant, MD, California Pacific Medical Center and John Lung, MD, Mountain States Tumor Institute.

. . . . . . . . . . . . . . . . . . . . . . . . .

Richard Parrish, Chair, EIFBCR; Malcolm Pike, PhD, USC/Keck Schoolof Medicine & Geoffrey Greene, MD, University of Chicago Laura Evans andPaul Delorey enrouteto Aconcagua

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Over 800 hikers joined hosts

Téa Leoni, Richard Roundtree

and

Kathy Smith

for the 6th Annual Expedition Inspiration LosAngeles Take-A-Hike which was held at Paramount Ranch,Santa Monica Mountains National Recreation Area, onSaturday, October 13. The event benefited

the Revlon/ UCLA

and

USC/Norris Lee Breast Centers

through UCLA’s Jonssonand the USC/Norris Comprehensive Cancer Centers.“Team USC” members were

Yuri Parisky, MD, OscarStreeter, MD, Susan Downey, MD, Christy Rusell, MD andMichael Press, MD.

Press has been the recipient of the grant

oard of Directors

xpedition Inspiration’s Board of Directors recently elected a new slate of off icers.

ichard Parrish

steps up as Chairman of the Board. He retired in 1999 from Boise- ascade Corporation as Senior Vice President of the Building Products Division.He has been a member of the EI team on Mt. Kilimanjaro (19,340’) and Mt.hitney (14,497’). Dick’s managerial expertise and climbing experience will be ansset to EI.

Heidi Mickelson

was elected Vice-Chair,

Kathy Jones

, Secretary, and

obert Kaplan

continues to serve as Treasurer. I is pleased to welcome two new members to our Board.

Julie Kilgrow

recently oved back to Boise, ID after 9 years as President and CEO of the United Way of he Greater Salt Lake Area. Her vast experience in fund raising will surely be ansset to our future growth.

Nancy Knoble

, Bend, OR, has also been elected to the oard of Directors. She is the Executive Director of the Central Oregon artnership. Nancy was a member of the original Aconcagua team and successfullyummitted the 22,841’ peak in 1995 with

Expedition Inspiration.

Both her prof es- ional and mountaineering skills will benefit our organization.

Expedition Inspiration

hanks you both for your willingness to get involved.e also want to thank “retiring” Board members,

Carol Harlig

a n d

eborah Van Dyke King.

Harlig served on the Board for five years and was anintegral part of our organization, and contributed a great deal to the success of ourFirst Annual Jazz Under The Stars” fundraiser. Van Dyke King has been a part of he EI team for many years, participating in both our Mt. Kilimanjaro climb andost recently, The Laura Evans Memorial Climb on Mt. Rainier in July, 2000. hank you, Carol and Debby, for continuing to support

Expedition Inspiration

.funds generated by the LA TAH.

Sherry Goldman

and

Helena Chang, MD, PhD

represented UCLA/ Revlon BreastCenter. Chang also is a recipient of the grant funds from theTake-A-Hike. Many thanks for your continued support.The event chaired by

BJ Dockweiler

who, with the incredi-ble Steering Committee, again raised almost $100,000 forbreast cancer research. Thank you all for your hard work anddedication. And a special thank you to

Deborah Liv Johnson

who sang “Amazing Grace,” and “A Mountain We WillClimb,” a song she wrote as a tribute to Laura Evans.

Hundreds head for the hills at Los Angeles

éa Leoni, Dr. Helena Chang, Revlon/UCLAreast Center and Dr. Yuki Parisky USC Norris BJ Dockweiler, Chair LA TAH; Roger Evans, Board Member and Katie Powell, Executive Director of EIFBCRRichard Roundtree Kathy Smith

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Take

Hike

Boise Take-A-Hike

The day couldn’t have been more per-fect when over 125 hikers climbed upTable Rock at the Sixth Annual BoiseTake-A-Hike, on October 6th atQuarry View Park to benefit

St. Luke’sMountain States Tumor Institute’sResearch Department.

S e rving asHonorary Chairs of the event were

Anita Kissée,

of NBC’s News Channel7, and breast cancer survivor,

Suzanne Locklear

of Suzanne’s SensationalFoods, which donates a portion of its sales to breast cancerresearch. Many of St. Luke’sdoctors and administra-tors attended the event that was chaired againby Board Member,Laurie Barrera. Thank you all!