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Doug GrantSVP & Head, Corporate Affairs
The Challenge of Reimbursement The Challenge of Reimbursement 
 
R
eimbursement decision-making for newmedications is changing rapidly
‡Increasing influence of health technology assessment(HTA) agencies and the associated complexity of formulary reviews, both locally and internationally‡The emergence of payer demands for ³risk-sharindeals and pricing concessions to reduce drug plan costgrowth‡Global downturn has exacerbated these trends‡At the same time, internally we are faced with the realityof global pricing imperatives and country launchsequencing considerations
 
E
volution -
R
eimbursement
E
nvironment
1970s1990s1980s2000s2010 and beyond
Traditional Model 
-market themedication aggressively todoctors after NoC
Cost-conscious Model 
-provideclinical data to supportreimbursement
Cost-constrained Model 
-provide clinicaland economic data to justify use of themedication as part of the therapeutic mix
Cost-containment Model 
-workhard to differentiate themedicine from alternatives
Negotiation Model 
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