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Prevent Cancer Foundation's Documents
Day 2 - Friday - 1100 AM - Tony Reeves
VOLCANO Studies: Establishing a public benchmark for evaluating change-in-size measurement of pulmonary Nodules Anthony P. Reeves Vision and Image Analysis Group School of Electrical and Computer Engineering Cornell University Presentation to the Lung Cancer Workshop VII, May 2010 VOLCANO Concept 1. Develop a benchmark set of image pairs for characterizing the performance of change-in-size lung nodule measurements 2. Establish benchmark results for the change in size measurements using a varie
Category:(not categorized)Reads:314Uploaded:05 / 27 / 2010ShareAdd to collectionDay 2 - Friday - 0930 AM - Marietta Anthony
The Critical Path Institute Improving the Innovation Process Marietta Anthony , PhD Critical Path Institute 1 Copyright C-Path 2010 Industry R&D Rising, but… Drug Approvals 17 in 2007 21 in 2008 19 in 2009 Copyright C-Path 2010 Productivity Death Spiral Booth and Zemmel, Nature Reviews in Drug Discovery 3:451-6, 2004 Copyright C-Path 2010 Copyright C-Path 2010 Need for Innovation We test drugs same way we did 30 years ago Need better tests for drug safety in humans Need mo
Category:(not categorized)Reads:249Uploaded:05 / 27 / 2010ShareAdd to collectionDay 2 - Friday - 0900 AM - Gudrun Zahlmann
Tumor volume and Clinical outcome – Is there a role for re-use of high quality quantitative image databases ? Gudrun Zahlmann Imaging Biomarker Roundtable Ad hoc committee on ‘Open Image Archives’ Imaging biomarkers for lung cancer • Diameter measurements of lung lesions – qualified biomarker. • Volumetric assessments , where possible: – Evidence that volume change is more sensitive than diameter change – No evidence so far that this is beneficial in terms of clinical development time. – Not
Category:(not categorized)Reads:376Uploaded:05 / 27 / 2010ShareAdd to collectionDay 2 - Friday - 0830 AM - Nick Petrick
Update on FDA Center for Devices and Radiological Health Investigation of Quantitative CT through Anthropomorphic Phantom Studies Nicholas Petrick1, Marios A. Gavrielides1, Rongping Zeng1, Lisa M. Kinnard2, Kyle J. Myers1 1 Division of Imaging and Applied Math, OSEL/CDRH/FDA 2 US Army Medical Research and Materials Command Outline • • • • Update on FDA CT phantom collection Reference Standard (truthing) Latest Analysis Summary N Petrick PCF Presentation May 14, 2010 2 Assessing Quantitat
Category:(not categorized)Reads:254Uploaded:05 / 27 / 2010ShareAdd to collectionDay 2 - Friday - 0800 AM - Robert Nordstrom
NCI Current/Planned Initiatives and Resources: Imaging as a Biomarker Robert J. Nordstrom, Ph.D. Program Director Cancer Imaging Program NCI May 14,2010 Presentation Outline Ø Ø Ø Ø Introduction Cancer Imaging Program Initiatives Quantitative Imaging Network Translational Research The Value of Imaging Reliable image data could lead to: Ø Earlier go/no-go decisions on compounds Ø Smaller clinical trials with fewer patients Ø Faster regulatory approval Cost Savings Reduced Time to Market
Category:(not categorized)Reads:614Uploaded:05 / 27 / 2010ShareAdd to collectionDay 1 - Thursday - 1610 PM - George Washko
Pulmonary Vascular Disease in COPD: What CT can teach us George Washko M.D. Applied Chest Imaging Laboratory Brigham and Women’s Hospital May 2010 Pulmonary Arterial Hypertension • Defined by mean pulmonary artery pressure > 25 mm Hg at rest, or > 30 mm Hg during exercise • Measured by non invasive echocardiogram but fraught with error COPD and PVD Estimated prevalence of disease 26–90%1,2 Presence associated with • Increased • Increased health care utilization3 mortality4 1. 2. 3
Category:(not categorized)Reads:291Uploaded:05 / 27 / 2010ShareAdd to collectionDay 1 - Thursday - 1550 PM - Raul San Jose Estepar
Introduction Emphysema Airways Airway Power Lung Cancer Workshop VII CT Im a g in g Ph e n ot yp e s in COPD Raúl San J osé Est épar, Ph.D. Laboratory of Mathematics in Imaging Applied Chest Imaging Laboratory Surgical Planning Laboratory Brigham and Women’s Hospital CT Imaging Phenotypes in COPD Introduction Emphysema Airways Airway Power Lung Cancer Workshop VII COPD: Chronic Obstructive Pulmonary Disease Definition: “Airflow limitation that is not fully reversible. The airflow
Category:(not categorized)Reads:335Uploaded:05 / 27 / 2010ShareAdd to collectionDay 1 - Thursday - 1330 PM - Larry Rot Hen Berg
Lung Cancer Workshop VII Bethesda , MD - May 13 , 2010 Risk : Perception and Reality Lawrence N. Rothenberg, Ph.D. Dept. of Medical Physics Memorial Sloan-Kettering Cancer Center New York, NY 1 CT Radiation Exposure/Dose/Risk: Why the concern? Brenner/Hall NEJM 2007 NCRP Report No. 160 and recent UNSCEAR Data CT the major source of medical radiation exposure to the public Man-made radiation (mostly medical) exposure in the US now equal to natural background Image Gently Campaign
Category:(not categorized)Reads:338Uploaded:05 / 27 / 2010ShareAdd to collectionDay 1 - Thursday - 1200 PM - Jonathon Silver Stein
Distributed Infrastructure for Imaging Jonathan C. Silverstein, MD, MS, FACS, FACMI University of Chicago and Argonne National Laboratory Virtual Organizations • • • • Distributed resources and people Linked by networks, crossing admin domains Sharing resources, common goals Dynamic R R R R R R R R VO-A R VO-B R R R R The Grid paradigm • Principles and mechanisms for dynamic VOs • Leverage service oriented architecture (SOA) • Loose coupling of Engineering data and services Biomedicine Compu
Category:(not categorized)Reads:204Uploaded:05 / 27 / 2010ShareAdd to collectionDay 1 - Thursday - 1130 AM - Tom Baer and Sean Bagshaw
Accelerating Lung Imaging Research Through Open Science Tom Baer Sean Bagshaw Optical Society of America May 13, 2010 – Washington, DC Interactive Science Publishing (ISP) • Enhance traditional publishing with 3D interactions and annotations • Deliver open-data directly into the hands of researchers • Disseminate open-source tools to the scientific community ISP History • Inspired by this meeting 5 years ago – Identified critical need for system to share data – Motivation was to accelerate d
Category:(not categorized)Reads:202Uploaded:05 / 27 / 2010ShareAdd to collection
