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R
ecently published research inpeer-reviewed medical journals isproviding strong evidence in sup-port of the age-old belief thatconsciousnesscanproducearealandmea-surable effect in the world.Threestudiesinparticularprovideacom-pellingviewof“consciousnessatwork.Thefirststudyofinterestlookedatthebiologicaleffects produced by individuals on them-selves when these individuals changed their states of consciousness through meditation.The second study explored the effects pro-duced in water by the intentions of a groupof people located on a different continent,and the third study examined what biologi-caleffectswereproducedinapersonwhena healer attempted to help that personthrough distant intentionality (DI) alone,with no physical contact. All three studiesproduced statistically significant results.
Consciousness and Self
The first study—Alterations in Brain andImmune Function Produced by Mindful-ness Meditation (
Psychosomatic Medicine.
2003;65:564-570)—was a randomized con-trolled trial that looked at what effects onbrain and immune function were pro-duced when people engaged in a mindful-ness meditation program. The researchteam—which included Richard J. David-son,PhD,andJonKabat-Zinn,PhD—mea-sured brain electrical activity before andimmediately after, and then 4 months af-teran8-weektrainingprograminmindful-ness meditation. Twenty-five subjectswere tested in the meditation group. Six-teen people in the wait-list control groupwere tested at the same points in time asthe meditators. At the end of the 8-week period, subjects in both groups were vac-cinated with influenza vaccine.The researchers found significant in-creases in left-sided anterior activation, apatternpreviouslyassociatedwithpositiveaffect, in the meditators compared withthe nonmeditators. They also found sig-nificant increases in antibody titers to theinfluenza vaccine among subjects in themeditation group as compared with thosein the wait-list control group. Finally, themagnitude of increase in left-sided activa-tion predicted the magnitude of antibodytiter rise to the vaccine.In their conclusion, the authors statedthat, “These findings demonstrate that ashort program in mindfulness meditationproducesdemonstrableeffectsonbrainandimmune function. These findings also sug-gest that meditation may change brain andimmune function in positive ways and un-derscore the need for additional research.”
Consciousness and Matter
The second study—Double-Blind Test of the Effects of Distant Intention on Water Crystal Formation (
Explore.
2006;2:408-411)—testedtheeffectsofhumanconscious-ness on water and revealed that when di-rected,ourintentionscanexertameasurableinfluence. Dean Radin, PhD, and Gail Hay-ssen,attemptingtoreplicatetheworkofJap-anese water researcher Masaru Emoto, took four bottles of the same brand of commer-cial bottled water and randomly designatedthemforeithertreatmentorcontrols.Apic-turewastakenofthetwobottlesselectedfotreatment and mailed to Emoto in Tokyo.On November 16, 2005, the approximately2,000 people who were gathered in Tokyofor the Second International Water for LifeConference were shown a picture of the In-stitute for Noetic Science campus, some5,000milesawayinCalifornia,andapictureofthetwobottlestobetreated.Emotothenledthe2,000peopleinafive-minute“prayeof gratitude” that was specifically directedtowards the water in California.The day after the conference, all four bottles—the two treated ones and the twocontrols—were sent to Tokyo. Fifty dropsof water from each bottle were frozen at
30°C for at least three hours, after whichthe drops were examined. If a crystallineshapewasfoundattheapexofanicedrop,then a digital image was taken. Slightlymore (60%) of the crystals came from thetreated bottles, which is not remarkable initself. However, 100 volunteers viewedand rated the 40 images, and the averageaesthetic ratings of the 40 crystals showeda highly significant difference (
.001),with the crystals from the treated bottles judged as being more beautiful than crys-tals from the control bottles.As the authors reported in their paper,“The results were consistent with the hy-pothesis that water treated with positiveintentions would result in more pleasingcrystal shapes.”
Consciousness and Others
The third study—Evidence for Correla-tions Between Distant Intentionality and
Call For Papers
Poverty and Human DevelopmentSubmission Deadline: April 15, 2007Publication Date: October 2007
EXPLORE: The Journal of Science and Healing 
will be participating in the Coun-cil of Science Editors Global Theme Issueon Poverty and Human Development. InOctober 2007
EXPLORE 
, along with 120other medical journals, will dedicate ed-itorial content to the issue of poverty as itrelates to human development andhealth. The purpose of this internationalcollaboration is to raise awareness, stim-ulate interest, and stimulate research intopoverty and human development.
EXPLORE 
is looking for case studies,clinical trials, systematic reviews, articlesfor the “Hypothesis” section, and col-umns that relate to this topic. Pleasesubmit online athttp://ees.elsevier.com/ explore.To see the full list of participating journals,please go to http://www.councilscienceeditors.org/globalthemeissue.cfm.
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EXPLORE January/February 2007, Vol. 3, No. 1 Matters of Note
MATTERS OF NOTE
Consciousness at Work:
Recent Research Points to the Power of Our Thoughts and Intentions
 
Brain Function in Recipients: A Func-tional Magnetic Resonance Imaging Anal-ysis (
 J Altern Complement Med.
2005;11:965-971)—put the question of distanthealing to a rigorous test. Jeanne Achter-berg, PhD, and a team at North HawaiiCommunity Hospital on the big island of Hawaii set out to prove—or disprove—thatmeasurable biological changes occur when a healer engages with a patient, eventhough there is no physical contact.To test the hypothesis, they recruitedeleven healers who were recognized as be-ing skilled by the communities theyserved. Their practices included, amongothers, Healing Touch, Hawaiian
pule 
, Pe-ruvian shamanism, Reiki, sound healing,and Qigoing. Each healer then chose a re-cipient for the DI experiment with whomhe or she felt some connection. Duringthe course of the study, each DI recipientspent 34 minutes in a functional magneticresonance machine while the assignedhealer, in an electromagnetic shield room,practiced his or her art in random two-minute “send” or “no-send” intervals, asassigned by the researchers.Significant differences in the brain scansof each of the recipients were found in the“send”and“no-sendperiods.Areasofhighactivation during the “send” sessions werethe anterior and middle cingulate cortex,precuneus, and frontal superior regions.Most notable is that these same areas wereactivated in all the recipients, regardless of which healing modality was used.The authors concluded that, “Thesefindings support previous research on dis-tant healing, suggesting that human inter-actions may directly affect others in waysthat are not entirely understood.”
The Elephant in the Living Room
“These studies are buttressed by scores of prior experiments pointing to correlationsbetweenintentionsandmeasurablechangesin the physical world,” says Larry Dossey,MD, Executive Editor of 
EXPLORE 
. “Thestudies fall into two broad categories: (1) lo-cal effects occurring within an individual, asin the Davidson et al study above, and (2)distant or nonlocal effects occurring be-tween individuals or objects, as in the Ra-din et al and Achterberg et al studiesabove. The distant or nonlocal effects of thought and intention offer profoundchallenges to the conventional notionthat mental phenomena are confined tothe individual brain and body. Yet the ev-idence favoring an expanded, nonlocalview of consciousness is abundant.”Perhaps the most complete review of this evidence is that of Wayne Jonas, MD,former director of the National Institutesof Health’s National Center for Comple-mentary and Alternative Medicine, andhis associate Cindy C. Crawford (JonasWB, Crawford CC.
Healing, Intention and EnergyMedicine.
NewYork,NY:ChurchillLivingstone; 2003: xv-xix). “Healing prac-tices using intention, prayer, mental focusand laying-on-of-hands have been usedsince the dawn of mankind. The tools of science have been applied to medicineandhealingforthelast200yearsbutrarelyto the evaluation of intentional healingpractices.Thisbookistheresultofathree-year effort to systematically and criticallysummarize existing research on inten-tional healing practices and related re-search in order to determine its evidence-base and to establish standards for itsscientific evaluation,” says Jonas. Jonas and Crawford found over 2,200published reports, including books, arti-cles,dissertations,abstractsandotherwrit-ings on spiritual healing, energy medicine,and mental intention effects. This in-cluded122laboratorystudies;80random-ized controlled trials; 128 summaries or reviews; 95 reports of observational stud-iesandnonrandomizedtrials;271descrip-tivestudies;casereportsandsurveys;1286other writings including opinions, claims,anecdotes, letters to editors, commentar-ies, critiques and meeting reports; and 259selected books. How good are these labo-ratory experiments and randomized con-trolled studies of the nonlocal effects of thought and intention? Jonas and Craw-ford graded the quality of studies by ap-plying strict CONSORT (ConsolidatedStandards of Reporting Trials) criteria.They gave the highest grade, an “A,” tomind-matter interaction studies, such asthe Radin et al study above. They gave a“B” to healing studies in general, such asthe above experiment of Achterberg et al.“The field of intentional healing re-search is in its infancy,” explains Jonas,“but the evidence and implications of these practices so far warrant a concertedscientific effort.”“The often-heard comments of skep-tics—that very few intentionality studiesexist, that they are hopelessly flawed, andthat they cannot be replicated—are false.Ignoring data does not make it go away,”adds Dossey. “We appear to be nearingthe day when the elephant in the livingroom of science—the local and nonlocaleffects of consciousness—will at long lastbe acknowledged.”
Exposure to PolychlorinatedBiphenyls May Reduce theEffectiveness of Vaccines inChildren
Why do some children, when vaccinated,producelesseramountsofantibodiesthanother children? A growing body of re-search suggests that part of the answer might lie in the degree to which the childhas been exposed to environmental toxi-cants.Most recently, according to a studypublished in the August 22, 2006, onlineedition of 
PLoS Medicine 
, increased peri-natal exposure to PCBs can adversely im-pact on immune responses to childhoodvaccinations. Researchers came to thisconclusion when the data revealed thatsome of the children in the study whowere exposed to polychlorinated biphe-nyls (PCBs) during the last months of pregnancy or shortly after birth did notproduce the necessary quantities of anti-bodies to make the tetanus and diphtheriavaccines 100% effective.The study—“Reduced Antibody Re-sponses to Vaccinations in Children Ex-posed to Polychlorinated Biphenyls”—looked at two groups of children in theFaeroe Islands, which are located in theNorth Atlantic. The traditional diet inthese islands includes whale blubber,some of which may be contaminated withPCBs. Blood and milk samples taken dur-ing pregnancy from the mothers were an-alyzed to determine the children’s prena-talPCBexposure.Afterroutinechildhoodvaccinations against tetanus and diphthe-ria, the two groups of children were exam-ined at age 18 months and 7 years, andblood samples were examined for tetanusand diphtheria antibodies.The findings showed an association be-tween increased PCB contamination andlowered antibody response to the vac-cines. At 18 months, the diphtheria anti-body concentration decreased by 24% for each doubling of the PCB exposure. At 7
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Matters of Note EXPLORE January/February 2007, Vol. 3, No. 1
 
years, the tetanus antibody responseshowed the strongest response and de-creased by 16% for each doubling of theprenatal exposure.“Ourstudyraisesconcernthatexposureto PCB and similar compounds may makechildhood vaccinations less efficient,”said Philippe Grandjean, DMSc, MD, ad- junct professor at Harvard School of Pub-lic Health and coauthor of the paper. Ex-posed children may also be moresusceptible to infections in general, hesaid.Polychlorinated biphenyls are a groupof 209 synthetic organic compounds thatwere manufactured in the United Statesbetween 1930 and 1977. But even thoughPCBs were banned from industrial use in1977, they do not readily break down inthe environment and therefore persist for a very long time.Polychlorinated biphenyls are presentin fatty fish worldwide and are knownfromlaboratorystudiestoaffectthe devel-opment of the immune system. The evi-dence that PCB exposure may have ad-verse effects on the immune function inchildren suggests that vaccine effective-ness may be an additional reason to pre-vent exposures to PCBs and other environ-mental pollutants. (For more informationon PCBs, please visit the US Agency for ToxicSubstancesandDiseaseRegistryWebsite at www.atsdr.cdc.gov/.) “PCB is just one of many pollutantsthat are known from rodent studies tohave a toxic impact on the immune sys-tem,” Grandjean said. He therefore sug-gests that these compounds be examinedfor their possible effect on the efficiencyof childhood immunizations.Carsten Heilmann of National Univer-sity Hospital in Copenhagen, Denmark,wasleadauthorofthestudy.Theworkwassupported by the National Institute for Environmental Health Sciences, the U.S.Environmental Protection Agency, theDanish Medical Research Council, andthe Danish Environmental ProtectionAgency.A PDF of the complete manuscript isavailable for free athttp://medicine.plosjournals.org/perlserv/?request
Botanical Medicine ResidencyProject Launched
The University of Arizona Program in In-tegrativeMedicine(PIM),incollaborationwith the Beth Israel/Albert Einstein De-partment of Family Medicine in NewYork, is piloting a new botanical medicinecourse for primary care residency pro-grams.The multisite project is designed to testthe feasibility and educational impact of incorporating a web-based teaching mod-ule on botanical medicine into residencytraining. “With the growing use of herbalmedicine by patients, residents must beeducated in their safe and effective use,”said Victoria Maizes MD, Executive Di-rector of the PIM. “Yet, many medicalschools and residency programs lack fac-ulty with expertise in this area and so areunabletoteachthesubject.
Botanical Med- icine: A Primer for Physicians
addresses thisneed.”Fourteen residency programs aroundthe nation in family medicine, internalmedicine, and obstetrics-gynecology resi-dencies have already signed up for the freeprogram. Participating programs can in-corporate the project into their own aca-demic schedule; however, the course is tobe considered a requirement. Residenciesslated to take part in the project includethe University of Arizona Departments of Family Medicine and Obstetrics and Gy-
Philippe Grandjean, DMSc, MD
Educate Your Patients About Environmental Health Risks
Visit Tox Town
The Specialized Information Services Divi-sion of the National Library of Medicine hascreated an online education resource calledTox Town—http://toxtown.nlm.nih.gov /  that explains about environmental healthrisks people might encounter in everyday life,in everyday places.Tox Town, which was created for the gen-eral public, offers:
information about the everyday locationswhere toxic chemicals can be found
nontechnical descriptions of chemicals
information on how the environment canimpact human health
Internet resources on environmental healthtopicsTox Town is a companion to the exten-sive information in the TOXNET collectionof databases that are typically used bytoxicologists and health professionals. Theinformation presented on chemical and en-vironmental concerns on the Tox Town Website has been derived from the TOXNET andMedlinePlus resources of the National Libraryof Medicine, as well as other authoritativesources.Chemicals included in Tox Town meet thefollowing criteria:
toxic
commonly encountered in the UnitedStates
known or expected to impact humanhealth
of interest to federal agencies that regu-late, research, or advise on a chemical’shealth effects, such as the EnvironmentalProtection Agency and the Agency forToxic Substances and Disease RegistryChemicals or substances that are volun-tarily ingested, such as drugs, dietary sup-plements, or caffeine, are not included in ToxTown.
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EXPLORE January/February 2007, Vol. 3, No. 1 Matters of Note
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