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Chapter 3
1. Atoms consist of electrons, protons, and neutrons.
2. Atoms of elements are distinguished by the
number of protons in the nucleus (the atomic
number).
3. Isotopes of an element have different numbers of
neutrons but the same number of p
+
and e
-
.
4. Isotopes of elements react identically (in most
chemical reactions).
5. Traditional chemical reactions focus primarily on
interactions in the outer valence electrons of
atoms.
Review:
A nucleus with a specified number of protons and
neutrons is a nuclide.
E
A mass number (number of p
+
+ number of n)
Z atomic number
Together, protons and neutrons are called
nucleons.
A
Z
Review of Nucleus
Nucleus: Particle Properties
Protons, neutrons, and electrons are all fermions (spin 1/2).
Protons and neutrons are heavy baryons (composed of 3
quarks).
[proton = up, up, down quarks and neutron = up, down, down]
Electrons are light leptons.
Particle Charge amu Spin
Proton +e 1.007276 1/2 +2.79
N
Neutron 0 1.008665 1/2 1.91
N
Electron e 5.485810
-4
1/2 +1.00
B
The Nucleus
Lets take a look at the nucleus, where the protons and
neutrons reside.
Breaking these apart can cause a large release of energy.
Protons
What is Radioactivity?
Elements that are RADIOACTIVE are
UNSTABLE because they have too many nucleons
or too much energy. In an attempt to become
STABLE, they give up particles or energy and this
is.
RADIOACTIVITY
From Latin radioto (to radiate)
Radioactivity
C
12
6
Stable
C
13
6
Stable
C
14
6
Unstable
RADIOACTIVE
Radioactivity
C
14
6
Unstable
RADIOACTIVE
The nucleus of this atom is very
heavy because it contains two
extra NEUTRONS
In order to become stable it needs
to get rid of some excess weight
Radioactivity
Because this atom is
unstable a NEUTRON
begins to break down
Neutron
Breakdown
C
14
6
Unstable
RADIOACTIVE
Neutron Breakdown
Neutrons are made up of
positively and negatively
charged particles
C
14
6
Unstable
RADIOACTIVE
The positive part of the
NEUTRON is actually a
PROTON
The negative part of the NEUTRON
is called a BETA particle
An anti-neutrino is also released
Neutron Breakdown
C
14
6
Unstable
RADIOACTIVE
= Neutron breaking down
The Negative Beta
Particle is released
|
This energy is
RADIOACTIVE
Having released the | particle
the NEUTRON now becomes
a PROTON
An anti-neutrino is also released
Neutron Breakdown
C
14
6
Unstable
RADIOACTIVE
N
14
7
Stable
NITROGEN
Lose NEUTRON
Gain PROTON
Neutron Breakdown Is
Just one way a element can become stable
Accompanied by Beta emission
And the conversion of a NEUTRON to a PROTON
Carbon-14 is a BETA emitter
There are other ways that an element can obtain
stability and this results in different types of
RADIATION
Nuclear Chemistry Introduction
Most chemical changes deal with the valence electrons
Nuclear chemistry deals with changes in the nucleus, often
accompanied by the release of a large amount of energy
Unstable nucleus spontaneously emits a particle or energy.
Radiation comes from the nucleus of an atom.
Radiation is energy in transit in the form of high speed
particles and electromagnetic waves
Radiation cannot be tasted, felt, or smelt, but has the potential to do a
great deal of damage
Radioactivity, or radioactive decay, is the spontaneous change of the
nuclei of certain atoms, accompanied by the emission of subatomic
particles and/or high-frequency electromagnetic radiation.
There are five principal particles or waves of radiation we will learn
about:
Alpha (o or
4
He
2+
)
Beta (|
or e
-
)
Positron (|
+
)
Gamma ()
Neutrons (n)
Summary Of Decay Types
e
e
symbol particle He
0
1
0
1 -
particle in neutrons and protons
particle in
(NOT Charge here!)
protons
4
2
+
=
Main Types Of Radioactive Decay
An alpha (o) particle has the same composition as a
helium nucleus (
4
2
He): two protons and two neutrons.
Beta (|
43
99m
Tc
43
99
Tc +
A gamma decay will have no change in the atomic number or atomic
mass
Much energy will
pass through without
any effect on
biological matter
Some energy may cause ionization
Neutron Radiation
Symbol:
0
1
n
It has a mass of one, no protons, and no charge
Very rare but very lethal
Generated in the explosion of nuclear
weapons
Neutron Bombs
Since this type of radiation is so specialized it
is not usually discussed in lectures such as
this
Types of nuclear radiation
Radiation
Type of
Radiation
Mass
(AMU)
Charge Shielding material
Alpha
Particle 4 2 Paper, skin, clothes
Beta
Particle 1/1836 1 Plastic, glass, light metals
Gamma
Electromag
-netic Wave 0 0
Dense metal, concrete,
Earth
Neutrons
Particle 1 0 Water, concrete
From: http://www.physics.isu.edu/radinf/properties.htm
Nuclear Physics
General Rules:
1) o emitted to reduce mass, only emitted if mass
number above 209
2) |
99m
Tc,
111
In,
18
F,
11
C,
64
Cu
Visualization of a biological process
Cancer, myocardial perfusion agents
Therapy
Particle emitters
Alpha, beta, conversion/auger electrons
188
Re,
166
Ho,
89
Sr,
90
Y,
212
Bi,
225
Ac,
131
I
Treatment of disease
Cancer, restenosis, hyperthyroidism
Nuclear Medicine: Imaging
consumption of Na
131
I
Source: Visuals Unlimited
Normal Thyroid An Enlarged Thyroid
Radiation Therapy
Radiation is used to deal with cancer and also
for diagnostics (imaging)
Rapidly growing cells hurt more by radiation
(same as chemotherapy exploits)
Cells that divide quickly are:
Cancerous cells
Hair follicles (loss of hair)
Digestive tract epithelial cells (nausea)
Try to localize radiation to the tumor
Radiation Therapy Methods
The goal is to minimize damage to
surrounding tissue by limiting
exposure.
Can achieve the same goal by
implanting seeds directly into
tumors.
Used for prostate cancers. Use bodys
natural processes for other cancers.
Iodine concentrates in thyroid, so
inject hot iodine.
Latest Cancer Research
Carbon nanotubules (nanotechnology) attached
to folate molecules, which are only found on
most cancerous cells
Sent into cancerous cells using this process
Near-infrared light radiation is then used to kill
the cells
The nanotubules heat up and kill them
Later, might attach nanotubules to antibodies to
target specific cancer cells
Tracer Studies
Tag molecules and introduce to the body and
then watch natural processes occur
You can monitor for the presence of the
radiation to see where it goes
Label a chemical with technetium-99 with 6
hour half life. Want to look at an organ? Pick
a molecule that heads there and tag it with Tc-
99
Often done for bone scans to look for cancer
Emission Tomography
Again, inject radioactive substance
Positron emission tomography is interesting
tomo = slice or section; graphy = writing or imaging
Use a positive beta emitter to tag a molecule
The positron annihilates with an electron to form
two gamma rays
Detect the gammas on an imaging basis as in CT
scans
Emission Tomography
Coincidence of signal detection establishes
the originating location.
Nuclear Magnetic Resonance
Protons have an intrinsic angular momentum called
spin
You can think about this for the time being as the
proton is like a little planet that rotates on its axis.
Since the proton has charge, this means we have a
rotating charge
We can consider the rotating charge to be a tiny
current
Nuclear Magnetic Resonance
We learned that a current going in a loop
generates a little magnetic field.
When we place the loop in an external
magnetic field, the magnetic field in the loop
tends to line up with the external magnetic field
You can convince yourself by considering the
forces on the charges in the current as they
circulate in the loop
Nuclear Magnetic Moment
Long story short, the axis of spin of the proton
wants to line up with the magnetic field that we
apply externally
The protons energy is lowest when the protons
magnetic field points in the same direction as the
external magnetic field
It is higher when it points in the opposite
direction
Nuclear Magnetic Resonance
The protons energy level splits into two states depending
on whether its spin is up or down. This is just like the
Zeeman effect for electrons. The energy difference
between these states corresponds to hf such that the
frequency is about 40 MHz if the field strength is 1T. The
energy is proportional to the field strength.
Nuclear Magnetic Resonance
If the magnetic field is modified by the presence of other
things like electrons in the neighborhood, then the
frequency will be slightly different. By measuring the
frequency of energy absorption by the protons we can
deduce its electron environment.
Nuclear Magnetic Resonance
This environment will depend on the chemical
composition of the neighborhood. The changing
frequency in different chemical environments is called the
chemical shift. Chemists use this idea to study the
structure of molecules.
Nuclear Magnetic Resonance
For our purposes, we want to form images, so we need to sense the
chemical shifts as a function of position in the body. Since different
body structures have different chemical environments, we can map the
structures by mapping the chemical shifts. This is MRI.
Nuclear Magnetic Resonance
To get position information, we apply a magnetic field
with a gradient (change in intensity from one location to
another. Then we can carefully determine position.
Low Level Effects of
Radiation
The effects of low level radiation are
hard to determine.
There are no directly measurable biological
effects at the background level.
Long term effects of radiation may include
heightened risk of cancer, but many
different things have been related to long
term heightened risk of cancer.
Separating out the different effects and
accounting for the different amounts of
low level radiation make this very difficult
to determine.
Low Level Effects of Radiation
At the cellular level, a dose of 100 millirems of
ionizing radiation gives on average 1
"hit" on a cell. (So the background radiation gives
about 2 hits per year to each cell.)
There are five possible reactions to a hit.
1. A "hit" on a cell can cause DNA damage that
leads to cancer later in life.
Note: There are other causes of DNA damage,
a relatively large amount from normal
chemical reactions in metabolism.
Low Level Effects of
Radiation
2. The body may be stimulated to
produce de-toxifying agents,
reducing the damage done by the
chemical reactions of metabolism.
3. The body may be stimulated to
initiate damage repair
mechanisms.
Low Level Effects of
Radiation
4. The cells may kill themselves (and
remove the cancer risk) by a process
called apoptosis, or programmed
cell death (a regular process that
happens when the cell determines that
things are not right).
5. The body may be stimulated to
provide an immune response that
entails actively searching for
defective cells - whether the
damage was done by the radiation
or by other means.
Low Level Effects of Radiation
There are two main theories:
1. Linear Hypothesis: A single radiation hit
may induce a cancer. Therefore, the best
amount of radiation is zero, and any radiation
is dangerous. The more radiation, the more
the danger.
This says effect #1 is always more important
than effects 2-5.
Low Level Effects of
Radiation
2. Hormesis Hypothesis: A small
amount of radiation is actually
good, but a large amount of
radiation is certainly bad.
Many chemicals behave this way - for
example B vitamins: we need some to
live, but too much is toxic. Vaccines are
also this way: we make ourselves a little
sick to build up our defenses against
major illnesses.
This theory says that at low levels, effects
2-5 are more important than effect 1.
Radiation Treatments
If high doses of radiation do bad things to
biological systems, can radiation be used as
a treatment?
Ask yourself this: does a knife do harm to biological
systems? If if does, why do surgeons use scalpels?
Fast growing cancer cells are more susceptible
to damage from radiation than normal cells.
For cancer treatment, localized (not whole-
body) doses regularly exceed 10,000,000
mrems.
Food
Irradiation
Food can be irradiated with rays from
60
Co or
137
Cs.
Irradiated milk has a shelf life of 3 mo.
without refrigeration.
USDA has approved irradiation of meats
and eggs.
Measurement of
Radioactivity
Devices
Film badges
photographic film exposed to
radiation
Geiger Counter
number of disintegrations
Scintillation counter
large number of samples in lab
Where does chemical
energy come from?
If chemicals are bound, then breaking the bonds does not release energy. It
requires external energy. This energy can come from the formation of stronger
bonds between the atoms, such as when you burn some sort of fuel. The fuel
bonds break, but stronger bonds are formed with oxygen for a net release of
energy. It can also come from the thermal energy of its surroundings, such as
when you break the ionic bonds in salt by dissolving it in water
Those are sources of net energy change, however. At the site of the bond
itself, this energy comes from the electromagnetic force (although there is
some KE of the electrons in addition to the electrical PE). The charges
(electrons and the nuclei) in chemicals are not perfectly evenly distributed,
causing net electrostatic fields.
When bonds are broken or formed, this motion of charges in the fields (which
exert a force on the charges) either absorbs or releases energy because the
charges are being pulled or pushed by the electric fields of all the other charges
present. If you want to think of it as an exchange of something, think of it as an
exchange of photons (leave virtual photons out of this, that's for much faster
processes involved in particle physics), which carry the electromagnetic force.
How about nuclear energy source?
The nucleus has its own forces, AND the electromagnetic force. Typical nuclear reactions
are dictated by the strong force, which holds the nucleus together. The weak nuclear force
predominantly causes beta decays.
But the queston is about the force between the parts of a nucleus, what holds it together,
and that is the strong force. The exact form of the strong nuclear force is still a mystery.
We have what we believe to be relatively exact models for the other 3 forces
(electromagnetism, the weak force, and gravitation), although there's some debate about
the extent of the knowledge we have about those. But the exact nature of the strong
nuclear force remains unknown. It results from the exchange of a zoo of virtual particles
(gluons and mesons), and it depends on too many things (such as the spins of the protons
and neutrons which are bound together in the nucleus) to go into here. But it's just another
force like gravitation and electromagnetism. The reason you don't feel it personally is that
it's very short-range, it essentiall ends at the boundaries of the nucleus itself.
Electromagnetic forces (like what holds magnets on your refrigerator) and gravitation are
long-range, so we're more familiar with them because they do operate on objects which
are of lengths that we can see and touch.
So, just like gravity pulls a rock towards the center of the Earth and makes it take energy
to roll uphill (or pick up energy as it rolls downhill), adding nucleons (protons and neutrons)
to or removing them from a nucleus requires energy. Think of the nucleus as a pit into
which nucleons fall, pulled down by a strange type of gravity that suddenly gets really
strong right next to and inside the hole. Now if you add a nucleon to a nucleus, it will
generally just scatter unless there's some way to convert this strong force into energy that
can be released. This can be in several forms, such as photons (gamma-rays are photons
emmited by such processes which have very high energies) or other particles with high
energies (say a proton fuses with a nucleus and a neutron is ejected). If the incoming
nucleon has enough energy, that energy can be converted into new (generally unstable)
particles. The nucleus is a complex place, so there's no single answer to that aspect of
your question.
Final Nuclear Notes
Mostly the energy released is in the form of kinetic energy of the
products of the reaction. For example, in the proton-proton chain that
powers the sun:
proton + proton -> deuteron + positron + neutrino + KE of products
The mass of the deuteron + positron + neutrino is less than the mass of
the two protons; this excess mass was converted to energy, in the form
of kinetic energy of the deuteron, positron, and neutrino.
Usually, if there is electromagnetic radiation involved, it is listed explicitly
(as a gamma ray), as in the next step in that chain:
proton + deuteron -> helium-3 + gamma + KE of products
So you get both electromagnetic radiation (the gamma ray) and energy,
in the form of kinetic energy of the helium-3 nucleus and the gamma ray.
Similarly, in fission reactions, the excess energy is in the form of kinetic
energy of the nuclear fragments.
In the following figure, this energy is referred to as "heat energy";
however, heat energy on an atomic scale is just kinetic energy
Measuring Health
Effects
Gamma rays (high energy photons) are very
penetrating, and so generally spread out
their ionizations (damage).
Beta rays (high speed electrons) are less
penetrating, and so their ionizations are
more concentrated.
Alphas (high speed helium nuclei) do not
penetrate very far since their two positive
charges interact strongly with the
electrons of the atoms in the material
through which they go.
Measuring Health Effects
This difference in penetrating ability (and
localization of ionization) leads us to
create an RBE (radiation biological
equivalent) factor and a new unit: the
rem. The more localized the ionization,
the higher the RBE.
# of rems = RBE * # of rads . This is
called an EFFECTIVE dose.
RBE for gammas = 1; RBE for betas = 1 to
2; RBE for alphas = 10 to 20.
Levels of Radiation
and Health Effects
In addition to our own radioactivity (and our
food), we receive radiation from:
a) space in the form of gamma rays; the
atmosphere does filter out a lot, but not
all;
b) the ground, since the ground has
uranium and thorium;
c) the air, since one of the decay products
of uranium is radon, a noble gas. If the
Uranium is near the surface, the radon
will percolate up and enter the air.
Nuclear Physics
size of atoms: take water (H
2
O)
density = 1 gm/cc,
atomic weight = 18 gm/mole, (alternately, get
mass of one molecule from mass spectrograph)
Avogadros number = 6 x 10
23
/mole
(1 cm
3
/gm)*(18 gm/mole) / (6x10
23
molecules/mole)
= 3 x 10
-23
cm
3
/molecule, so
d
atom
= V
1/3
= 3 x 10
-8
cm = 3 x 10
-10
m.
Mass Defect & Binding
Energy
By definition, mass of
6
C
12
is 12.00000 amu.
The mass of a proton (plus electron) is 1.00782
amu. (The mass of a proton by itself is 1.00728 amu,
and the mass of an electron is 0.00055 amu.)
The mass of a neutron is 1.008665 amu.
Note that 6*m
proton+e
+ 6*m
neutron
> m
C-12
.
Where did the missing mass go to?
Mass Defect & Binding
Energy
Similar question: The energy of the
electron in the hydrogen atom is -
13.6 eV. Where did the 13.6 eV
(amount from zero) go to in the
hydrogen atom?
Answer: In the hydrogen atom, this
energy (called the binding energy)
was emitted when the electron fell
down into its stable orbit around
the proton.
Mass Defect & Binding
Energy
Similarly, the missing mass was converted into
energy (E=mc
2
) and emitted when the
carbon-12 atom was made from the six
protons and six neutrons:
Am = 6*m
proton
+ 6*m
neutron
- m
C-12
=
6(1.00782 amu) + 6(1.008665 amu) - 12.00000 amu
= .099 amu; BE = Am*c
2
=
(0.099 amu)*(1.66x10
-27
kg/amu)*(3x10
8
m/s)
2
= 1.478x10
-11
J*(1 eV/1.6x10
-19
J) = 92.37 MeV
Mass Defect & Binding
Energy
For Carbon-12 we have:
BE = Am*c
2
= 92.37 MeV
If we consider the binding energy per
nucleon, we have for carbon-12:
BE/nucleon = 92.37 MeV /12 = 7.70
MeV/nucleon.
The largest BE/nucleon happens for
the stable isotopes of iron (about
8.8 MeV/nucleon).
Mass Defect and Binding
Energy
Be careful: The fact that isotopes of iron have the
highest binding energy per nucleon is NOT related to
iron being a hard metal. The fact of being a metal is
determined by the ELECTRONIC shells, NOT the
nuclear binding.
Note: Chemical binding energies (ionization energies)
are on the order of several eV. Nuclear binding
energies are on the order of several MeV. Nuclear
energies are thus an order of a million times
stronger than electrical binding energies!
Plot of energy versus
the separation distance
Nucleus: Particle Potential Wells
Electron is only bound with negative total energy, and can never escape.
Nucleon can be bound with positive total energy, and can escape by
tunneling through the Coulomb barrier nuclear decay processes.
Leads to radioactive processes.
Electron Coulombic Potential Nucleon Nuclear Potential
E
n
e
r
g
y
Radius r
Radiation Processes: |
Decay (e
Emission)
Parent nucleus decays to daughter nucleus plus electron and
anti-neutrino.
Anti-neutrino is 3rd particle that explains range of electron kinetic
energies.
If atom (Z) has greater mass than its right neighbor (Z+1), then
|
decay is possible.
Free neutron can decay into a proton.
t
1/2
= 10.8 min, Q = 939.57 (938.28 + 0.511) = 0.78 MeV
( ) ( )
2
1
1
*electron mass included in daughter nucleus
( )
A A
Z
A A
Z Z
Z
X D
Q MeV Ma
e v
ss X Mass D c
+
+
+ +
(
=
Positron Emission Tomography (PET) A new and
Important Tool in Imaging Research
In the technique of positron Tomography, a positron emitting isotope
Is included into a molecule that is incorporated into a chemical reaction.
The positron emitted during the decay of the isotope will analite with an
Electron and emit two 511 kev gamma rays that can then be detected,
and the location of the decaying isotope isolated accurately.
B
+
+ e
-
Energy Two Gamma rays at 180
o
e
-
+ B
+
511 kev
511 kev
Common Positron emitting Isotopes:
15
O, T
1/2
= 122s ;
18
F, T
1/2
= 1.83 hr
11
C, T
1/2
= 20.3 min ,
13
N, T
1/2
= 9.97 min , ETC
The two gamma
rays come away
at 180
o
.
Positron Emission Tomograph
The Tomograph is an
instrument that is a ring
of gamma ray detectors
that react very fast to
gamma rays, and by
measuring the time each
detector receives the signal
one can locate the point of
origin of the gamma ray to a precision of + 1 cm in a
human being or any other physical object, with out
any in vivo investigation. The detectors must have a
capability of measuring up to + 250 ps per pulse.
_
_
Four Known Forces
Two familiar kinds of interactions:
gravity (masses attract one another) and
electromagnetism (same-sign charges repel, opposite-
sign charges attract)
What causes radioactive decays of nuclei ?
Must be a force weak enough to allow most atoms to
be stable.
What binds protons together into nuclei ?
Must be a force strong enough to overcome repulsion
due to protons electric charge
Previously, we peered inside the atom
We recalled that electrons orbit
the atoms massive nucleus and
determine an elements chemical
behavior.
We explored the proton and
neutron content of nuclei and the
phenomena of radioactivity,
fission, and fusion they make
possible.
Today well look inside
the nucleons
themselves.
Fundamental particles in the
Standard Model are:
Leptons
Quarks
Intermediate Gauge Bosons
Anti-matter
Each kind of elementary particle has a counterpart
with the same mass, but the opposite electric charge,
called its anti-particle.
Electron: m= .0005 GeV, charge = +1, symbol e
-
Positron: m = .0005 GeV, charge = -1, symbol e
+
The anti-particle has a bar over its symbol:
Anti-proton is written , anti-neutrino is
Anti-matter is rare in the explored universe
Its created in cosmic rays and particle accelerators
and some radioactive decays.
When a particle and its anti-particle collide, they
annihilate one another in a flash of energy.
p
v
Where do the elements come from?
Stability diagram
Heavy elements can fission
into lighter elements.
Light elements can undergo
fusion into heavier elements.
Elements from helium to iron were
manufactured in the cores of stars by fusion.
Heavier elements are metastable and were
made during supernovae explosions.
Fission: Chain Reaction
Use neutrons from fission process to initiate other
fissions!
1942: Fermi achieved first self-sustaining chain
reaction.
For nuclear bomb, need
more than one neutron
from first fission event
causing a second event.
For nuclear power plant,
need less than one
neutron causing a second
event.
Chain reaction
For reaction to be self-sustaining, must have
CRITICAL MASS.
Figure 21.11: Upon capturing a neutron, the
235
U nucleus undergoes fission to produce two
lighter nuclides, free neutrons (typically three),
and a large amount of energy.
Figure 21.12: Representation of a fission
process in which each event produces two
neutrons, which can go on to split other
nuclei, leading to a self-sustaining chain
reaction.
Figure 21.13: If the mass of the fissionable
material is too small, most of the neutrons
escape before causing another fission event;
thus the process dies out.
Nuclear reactors
Fusion
Light nuclei are more stable when
combined
Tremendous energy released
Hydrogen bombs and Fusion
power?
Schematic diagram of a cyclotron
Physicist works with a small cyclotron at
the University of California at Berkeley.
Source: Corbis
CERN, the
world's largest
particle
accelerator,
lies at the foot
of the Jura
Mountains
near Geneva,
Switzerland.
Diagram of a linear accelerator
Accelerator
tunnel at
Fermilab, a
high-energy
particle
accelerator in
Batavia, Illinois.
Source: Fermilab Batavia, IL
Units used for Nuclear Energy Calculations
electron volt - (ev)
The energy an electron acquires when it moves through
a potential difference of one volt:
1 ev = 1.602 x 10
-19
J
Binding energies are commonly expressed in units
of megaelectron volts (Mev)
1 Mev = 10
6
ev = 1.602 x 10
-13
J
A particularly useful factor converts a given mass defect
in atomic mass units to its energy equivalent in electron
volts:
1 amu = 931.5 x 10
6
ev = 931.5 Mev