these lines are whitish dots visible in a cross-section scattered through both the outerand inner layers. Internally reddish-brown to yellow; odor slight; taste aromatic andbitter.
: Aspidosperma is very rich in alkaloids, six having been discoveredthus far; the most important are
. A peculiar sugar, quebrachite, is also present, and tannin, 3 to 4 percent. Cardiac tonic.
Its special action, however, is upon the respiration
,lessening the rate and increasing the amplitude of the respiratory movements; it ischiefly used in asthmatic dyspnoea. Dose: 5 to 30 gr. (0.3 to 2 Gm.).
.—Microscopical elements of: See Part iv, Chap. I, B.
Preparation of Aspidospermine
.—Treat alcoholic extract with alkaline chloroform;dissolve chloroformic extract in acidulated (H
) water and precipitate with NaOH;dissolve precipitate (mixed alkaloids) in boiling alcohol and cool, when alkaloids willcrystallize.To separate aspidospermine, crystallize from dilute HCl, when this alkaloid willremain in the mother liquor, from which it may be removed by neutralization andrecrystallization. As found in commerce, this alkaloid is a mixture of this and theother associated principles, among which quebrachine is the most important. Crudeaspidospermine sulphate is a commercial article, is deliquescent and unstable; it ismuch more soluble in water than the alkaloid.
Dose: 5 to 30 drops (0.3 to 2 Mils).448.
F. Mueller.—AUSTRALIAN FEVER BARK.Tonic, antiperiodic. Dose of fl'ext.: 2 to 8 drops (0.13 to 0.5 mil).449.
R. Brown.—DITA. A tree growing in the PhilippineIslands, the bark of which is used in India as a substitute for cinchona. Dose of fl'ext.:2 to 8 drops (0.13 to 0.5 mil) .450.
.—The bark of
Wallr. Has been usedin Europe and is still extensively employed in India in dysentery. Its alkaloid,conessine, enters commerce.
STROPHANTHUSSTROPHANTHUSThe ripe seed of
Oliver or of Strophanthus hispidus DeCandolle, deprived of its long awn.BOTANICAL CHARACTERISTICS.—A woody climber, ascending to the tops of high trees, from which it hangs in festoons.
in terminal cymes, gamopetalous,the lobes prolonged into long, tail-like points, often 8 or 9 inches long.
Sayre’s Materia Medica part V - Page 3