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MCQ Chemotheraputics

MCQ Chemotheraputics

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Published by Parikshit Choudhari

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Categories:Types, Research, Science
Published by: Parikshit Choudhari on Aug 06, 2012
Copyright:Attribution Non-commercial

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10/17/2014

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Chemotherapy Practice Questions: Set 1
Multiple-choice quiz
Choose the correct answer for each question.Show questions one by one1.
 
Mechanism of cellular resistance to polyfunctional alkylating drugs:1.
 
? decreased DNA repair capability2.
 
? reduced production of glutathione3.
 
? increased permeability to the drug4.
 
? none of the above2.
 
Does not have direct vesicant effects:1.
 
? mechlorethamine (Mustargen)2.
 
? carmustine (BNCU,BiCNU)3.
 
? cyclophosphamide (Cytoxan)4.
 
? A & B3.
 
Polyfunctional alkylating agent used specifically for chronic myeloid leukemia:1.
 
? cyclophosphamide (Cytoxan)2.
 
? busulfan (Myleran)3.
 
? thiopeta (Thioplex)4.
 
? dacarbazine (DTIC)4.
 
Major toxicity of alkylating drugs:1.
 
? alopecia2.
 
? myelosuppression3.
 
? renal damage4.
 
? hepatic failure5.
 
Most useful alkylating drug currently available:1.
 
? melphalan (Alkeran)2.
 
? cyclophosphamide (Cytoxan)3.
 
? lomustine (CCNU,CeeNU)4.
 
? thiopeta (Thioplex)6.
 
Most common route of administration for melphalan (Alkeran):1.
 
? oral2.
 
? iv7.
 
Most common route of administration for cyclophosphamide (Cytoxan):1.
 
? iv2.
 
? oral8.
 
Nitrosourea with minimal bone-marrow suppression and effective in treating pancreatic,islet cell carcinoma.1.
 
? lomustine (CCNU,CeeNU)2.
 
? carmustine (BNCU,BiCNU)3.
 
? streptozocin (Zanosar)

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