Unit 2: Science and the World of WorkGlaxoSmithKline Case Study
Task 1
1a.
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Illustrate the aims, structure and functions of GlaxoSmithKline (GSK).
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Is the organisation profit or non-profit making?
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Does the organisation provide a service or make a product?
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Use flow charts and diagrams to illustrate the structure of GSK.
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What are the functions of the different departments of GSK?
P1
1b.
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Describe how the different departments within GSK work together with each other
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Explain how the products provided by GSK contribute to society.
M1
1c.
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Describe the advantages and disadvantages that GSK has for the lives of people in the areaand for the general public.
You should consider the effect on the local economy and of employmentopportunities.
should consider the effect of the organisation on the local environment, suchas transport and road usage, air quality, water and waste management.
D1Task 2
2a.
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Zidovudine is an anti-HIV compound produced by GSK for the treatment of patients sufferingfrom AIDS. Investigate and describe this product.
P2
2b.
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Zidovudine attacks HIV by preventing the work of an enzyme that is essential for thereplication of the virus
Investigate the lifecycle of a virus
Carry out research into the ‘mode of action’ of Zidovudine.
M2
2c.
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Zidovudine is known as a ‘reverse transcriptase inhibitor.’ The pharmaceutical companyMerck is a rival to GSK. Merck produces a compound called Crixivan. Crixivan is known as a‘protease inhibitor.’ Compare the Zidovudine with Crixivan. You could compare
Mode of action
Structure of the compound
Route of administration
Cost
Side effects
Risks associated with taking each product
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