Welcome to Scribd, the world's digital library. Read, publish, and share books and documents. See more
Standard view
Full view
of .
Look up keyword
Like this
1Activity
0 of .
Results for:
No results containing your search query
P. 1
A Review of the Relationship between Alcohol and Oral Cancer

A Review of the Relationship between Alcohol and Oral Cancer

Ratings: (0)|Views: 7|Likes:
An essay for the 2011 Undergraduate Awards Competition by John Reidy. Originally submitted for Oral Surgery at Trinity College, Dublin, with lecturer Prof. Leo Stassen in the category of Medical Sciences
An essay for the 2011 Undergraduate Awards Competition by John Reidy. Originally submitted for Oral Surgery at Trinity College, Dublin, with lecturer Prof. Leo Stassen in the category of Medical Sciences

More info:

Published by: Undergraduate Awards on Aug 29, 2012
Copyright:Attribution Non-commercial

Availability:

Read on Scribd mobile: iPhone, iPad and Android.
See more
See less

01/22/2014

 
A Review of the Relationship between Alcohol andOral Cancer
 
Abstract
This paper aims to review the current literature regarding the association between alcoholconsumption and oral cancer. The authors have discussed the constituents of alcohol-containing beverages, the metabolism of ethanol and its effect on the oral microflora. The local and systemiccarcinogenic effects of alcohol have been detailed. The beneficial effects of alcohol consumptionon general health have also been considered. A possible relationship between alcohol-containingmouthrinses and oral cancer has been suggested in the literature. The authors conclude that thisrelationship has not yet been firmly established. However, the use of alcohol-containingmouthrinses in high risk populations should be restricted, pending the outcome of further research.
 
Introduction
Alcohol consumption has long been recognized as one of the major modifiable risk factors for thedevelopment of oral cancer. The excessive consumption of alcohol-containing beverages is alsoassociated with an increased risk of developing other cancers of the head and neck such as pharyngeal and laryngeal cancer, as well as other chronic diseases including heart disease,Alzheimer’s disease, stroke, liver disease, cancer, chronic respiratory disease, diabetes mellitusand bone disease.Despite the definite association between chronic alcohol consumption and oral cancer, theexact role of alcohol in the pathogenesis of the disease is not fully understood, and the following point should be considered: Not all oral cancer patients consume alcohol, and not all people whodrink alcoholic beverages develop oral cancer. In addition, smoking and alcohol consumption aresynergistic risk factors for oral carcinogenesis. This makes it difficult to assess the effects of thesefactors individually, with approximately 75% of all oral cancers arising in association with bothalcohol and tobacco use. Difficulties also arise in establishing an accurate measurement of alcoholintake, with variation in quantity, type and alcohol concentration existing between patients. Patientsubjectivity of alcohol consumption also impacts upon the accuracy of the measurement of alcoholintake, thus making it difficult to fully evaluate the role of alcohol in the development of oralcancer.This article will review the most recent literature on the effects of alcohol on the oral mucosa, andthe possible mechanisms by which alcohol is thought to act as a carcinogen. The article will alsoconsider the possible link between alcohol-containing mouthrinsees and oral cancer.

You're Reading a Free Preview

Download
scribd
/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->