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Shape Optimization of Stainless Steel Coronary Stents

Shape Optimization of Stainless Steel Coronary Stents

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This work aims to perform a structural shape optimization of a cardio-vascular stent, a mesh-like scaffold used in treating atherosclerosis. A parametric study is carried out to establish trends in structural performance with respect to shape changes, and a structural shape optimization procedure shows correlating trends and optimum shapes. A peer-reviewed conference paper on this work was published and presented.
This work aims to perform a structural shape optimization of a cardio-vascular stent, a mesh-like scaffold used in treating atherosclerosis. A parametric study is carried out to establish trends in structural performance with respect to shape changes, and a structural shape optimization procedure shows correlating trends and optimum shapes. A peer-reviewed conference paper on this work was published and presented.

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Published by: Undergraduate Awards on Sep 01, 2012
Copyright:Attribution Non-commercial

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02/16/2014

 
University College Cork 
Coláiste na hOllscoile CorcaighDepartment of Civil & Environmental Engineering
Shape optimisation of stainless steel coronary stents
Rory Clune
Supervisor: Dr. Denis KelliherSubmitted as part of BE (Civil) degreeModule CE4002April 2008
 
Introduction
Coronary stents are tubular meshes inserted into diseased coronaryarteries as a means of treating atherosclerosis, more commonly known asheart disease. The purpouse of this project is to identify and establishrelationships between the shape of stainless steel coronary stents andtheir structural performance. The technique of shape optimisation is to beapplied to determine optimum stents.A geometric modeller has previously been developed to model thecoronary stents
17
, as has a finite element package which analyses thestents generated by this modeller. This project build on this work alreadydone by initially building a thorough understanding of the work alreadycompleted, developing initial trends and relationships between shape andstructural properties, finally by applying a more formal shape optimisationprocedure to the problem.All software used in and written for this project is described inappendix 8.2. It may prove worthwhile to reference this appendix duringthe reading of this report.
 
Contents:
 
1.
Introduction to relevant concepts
pp. 1-11
1.1
Atherosclerosis..
1
1.2
Restenosis..
4
1.3
Coronary Stents..
5
1.4Shape Optimisation
1.4.1
Basic optimisation concepts..
6
1.4.2
Extension to shape optimisation..
7
1.5
NURBS theory..
7
2.
Geometric modelling and finite element analysis
pp. 12-26
2.1
General overview..
12
2.2
Geometric modeller..
13
2.3
Modifications made to geometric modeller..
16
2.3.1
Integration – development of a ‘black box’..
16

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