The aim of this dissertation was to ascertain how the Irish hospital pharmacist cancontribute to the appropriate use of antimicrobials to treat infection. Both descriptiveand primary research reports were identified and included.It has been estabished that global rates of antimicrobial resistance are rising andinappropriate prescribing and misuse of anti-infectious agents are causual factors. Asa result, the Strategy for the control of Antimicrobial Resistance in Ireland (SARI) has been initiated, with the hospital pharmacist identified as a key individual in this project. It was found that the SARI pharmacist can contribute to the appropriate use of antimicrobials through audit, education and prescribing initiatives. However, it wasnoted that SARI pharmacists lack training and participation in antimicrobialstewardship is low, and concomitantly, an ever gradual rise in antibiotic consumptionis occuring in Irish hospitals. From analysis of the literature, it is evident thatantimicrobial stewardship results in decreased antibiotic use and reduced resistanceeven though there are costs, issues and challenges associated with the programmes.It was concluded that an increase in the number of SARI pharmacists and their participation in stewardship is essential to ensure a uniform approach to resistance. ASARI implementation body is necessary to get the project off the ground in somehospitals and accredited training and standards for antibiotic pharmacists is required.Universal electronic databanks would also be useful in curbing antimicrobialconsumption as well as the requirement for local antibiotic formularies to control usein the community.