DRUG, VITAMIN, MINERAL, HERB INTERACTIONS
5-HTP should be used with caution, if at all, in people taking selectiveserotonin reuptake inhibitors (SSRIs) and monoamine oxidaseinhibitors (MAOIs), two types of antidepressant medications.Specifically, the likelihood of developing unpleasant side effects,including serotonin syndrome (characterized by mental statuschanges, rigidity, hot flashes, rapidly fluctuating vital signs, andpossibly coma) is greater if you combine 5-HTP with the drugssumatriptan, tramadol, trazodone, venlafaxine, and zolpidem. Taking5-hydroxytryptophan with carbidopa, a medication used to treatParkinson's disease, has been associated with side effects, includingscleroderma-like illness (the skin becomes hard, thick, and inflamed).Using this combination should be avoided except under the supervisionof your healthcare provider.
Alpha-Linolenic Acid (ALA)
The combination of alpha-linolenic acid (ALA) and lovastatin may offerbenefits to patients on lovastatin therapy. However, additional studiesin humans are needed to confirm these findings. You should consultwith your healthcare provider before taking ALA if you are currentlytaking lovastatin.
The combination of aloe vera and glyburide, a medication used to treat Type II diabetes, may help control blood sugar and triglyceride levels inthe blood. However, you should not use aloe vera in these instanceswithout first consulting with your health care practitioner. Diabeticpatients using aloe vera either alone or in combination with otherantidiabetic medications need to be monitored closely by health careproviders to avoid potential complications from low blood sugar levels.Aloe vera may enhance the effects of hydrocortisone on swelling.Again, consult with your doctor before using aloe with hydrocortisonefor conditions involving inflammation or swelling.
In an animal study, alpha-lipoic acid supplements reduced side effects,particularly toxicity to the ear, associated with the antibiotics, amikacinand gentamicin. Additional studies are needed to confirm these effects