Welcome to Scribd. Sign in or start your free trial to enjoy unlimited e-books, audiobooks & documents.Find out more
Download
Standard view
Full view
of .
Look up keyword
Like this
1Activity
0 of .
Results for:
No results containing your search query
P. 1
CABERGOLINE safety2

CABERGOLINE safety2

Ratings:
(0)
|Views: 12,050|Likes:
Published by Kane Smith

More info:

Published by: Kane Smith on Sep 28, 2012
Copyright:Attribution Non-commercial

Availability:

Read on Scribd mobile: iPhone, iPad and Android.
download as PDF, TXT or read online from Scribd
See more
See less

03/04/2014

pdf

text

original

 
 
1.IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING
Material Name: Cabergoline Tablets
Trade Name:
DOSTINEX; CABASER
Chemical Family:
Mixture
Intended Use:
Pharmaceutical product used for lactation inhibition
2. HAZARDS IDENTIFICATION
Appearance:
White tablets
Statement of Hazard:
Non-hazardous in accordance with international standards for workplace safety.
Additional Hazard Information:Short Term:
 Active ingredient may be harmful if swallowed. (based on animal data) . Accidental ingestionmay cause effects similar to those seen in clinical use.
Known Clinical Effects:
Ingestion of this material may cause effects similar to those seen in clinical use includingnausea, vomiting, abdominal cramps, anorexia, diarrhea, and constipation. This drug maydecrease the quantity/quality of breast milk.
EU Indication of danger:
Not classified
Australian Hazard Classification(NOHSC):
Non-Hazardous Substance. Non-Dangerous Goods.
Note:
This document has been prepared in accordance with standards for workplace safety, whichrequire the inclusion of all known hazards of the active substance or its intermediatesregardless of the potential risk. The precautionary statements and warnings included may notapply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.
 _______________________________________________________________________________________________________ 
CABERGOLINE TABLETSVersion: 1.3
MATERIAL SAFETY DATA SHEET
Page 1 of 6
Pfizer IncPfizer Pharmaceuticals Group235 East 42nd StreetNew York, New York 100171-212-573-2222Pfizer LtdRamsgate RoadSandwich, KentCT13 9NJUnited Kingdom+00 44 (0)1304 616161Emergency telephone number:CHEMTREC (24 hours): 1-800-424-9300
Revision date: 18-Sep-2008
Emergency telephone number:ChemSafe (24 hours): +44 (0)208 762 8322Contact E-Mail:
pfizer-MSDS@pfizer.com
 
MATERIAL SAFETY DATA SHEET
 _______________________________________________________________________________________________________ 
3. COMPOSITION/INFORMATION ON INGREDIENTS
HazardousIngredientCAS NumberEU EINECS/ELINCS ListClassification%
Cabergoline81409-90-7Not listedXn;R221.25
 
IngredientCAS NumberEU EINECS/ELINCS ListClassification%
Leucine61-90-5200-522-0Not Listed*Lactose NF, anhydrous63-42-3200-559-2Not Listed*
 
Additional Information:
* ProprietaryIngredient(s) indicated as hazardous have been assessed under standards for workplacesafety.
For the full text of the R phrases mentioned in this Section, see Section 16
 
4. FIRST AID MEASURES
Eye Contact:
Flush with water while holding eyelids open for at least 15 minutes. Seek medical attentionimmediately.
Skin Contact:
Remove contaminated clothing. Flush area with large amounts of water. Use soap. Seekmedical attention.
Ingestion:
Never give anything by mouth to an unconscious person. Wash out mouth with water. Do notinduce vomiting unless directed by medical personnel. Seek medical attention immediately.
Inhalation:
Remove to fresh air and keep patient at rest. Seek medical attention immediately.
Symptoms and Effects of Exposure:
For information on potential signs and symptoms of exposure, See Section 2 - HazardsIdentification and/or Section 11 - Toxicological Information.
5. FIRE FIGHTING MEASURES
Extinguishing Media:
Use carbon dioxide, dry chemical, or water spray.
Hazardous Combustion Products:
Formation of toxic gases is possible during heating or fire.
Fire Fighting Procedures:
During all fire fighting activities, wear appropriate protective equipment, including self-contained breathing apparatus.
Fire / Explosion Hazards:
Not applicable
6. ACCIDENTAL RELEASE MEASURES
Health and Safety Precautions:
Personnel involved in clean-up should wear appropriate personal protective equipment (seeSection 8). Minimize exposure.
Measures for Cleaning / Collecting:
Contain the source of spill if it is safe to do so. Collect spilled material by a method thatcontrols dust generation. A damp cloth or a filtered vacuum should be used to clean spills of dry solids. Clean spill area thoroughly.
Measures for EnvironmentalProtections:
Place waste in an appropriately labeled, sealed container for disposal. Care should be taken toavoid environmental release.
 _______________________________________________________________________________________________________ 
CABERGOLINE TABLETS
Revision date: 18-Sep-2008Material Name: Cabergoline TabletsVersion: 1.3Page 2 of 6
 
MATERIAL SAFETY DATA SHEET
 _______________________________________________________________________________________________________ Additional Consideration for LargeSpills:
Non-essential personnel should be evacuated from affected area. Report emergencysituations immediately. Clean up operations should only be undertaken by trained personnel.
7. HANDLING AND STORAGE
General Handling:
Restrict access to work area. If tablets or capsules are crushed and/or broken, avoid breathingdust and avoid contact with eyes, skin, and clothing. When handling, use appropriate personalprotective equipment (see Section 8). Wash thoroughly after handling. Releases to theenvironment should be avoided. Review and implement appropriate technical and proceduralwaste water and waste disposal measures to prevent occupational exposure or environmentalreleases. Potential points of process emissions of this material to the atmosphere should becontrolled with dust collectors, HEPA filtration systems or other equivalent controls.
Storage Conditions:
Store as directed by product packaging.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering Controls:
Engineering controls should be used as the primary means to control exposures.
Environmental Exposure Controls:
Refer to specific Member State legislation for requirements under Community environmentallegislation.
Personal Protective Equipment:
Refer to applicable national standards and regulations in the selection and use of personalprotective equipment (PPE).
Hands:
Not required for the normal use of this product. Wear protective gloves when working withlarge quantities.
Eyes:
Not required for the normal use of this product.Wear safety glasses or goggles if eye contactis possible.
Skin:
Not required for the normal use of this product. Wear protective clothing when working withlarge quantities.
Respiratory protection:
Not required for the normal use of this product. Whenever excessive air contamination (dust,mist, vapor) is generated, respiratory protection, with appropriate protection factors, should beused to minimize exposure.
9. PHYSICAL AND CHEMICAL PROPERTIES:10. STABILITY AND REACTIVITY
Stability:
Stable at normal conditions
Conditions to Avoid:
None known
Incompatible Materials:
 As a precautionary measure, keep away from strong oxidizers
Hazardous Decomposition Products:
Nitrogen oxides (nox) Carbon oxides
 _______________________________________________________________________________________________________ 
CABERGOLINE TABLETS
LeucineLatvia OEL - TWA
Listed
Revision date: 18-Sep-2008CabergolineMaterial Name: Cabergoline TabletsPhysical State:
Tablets
Color:
White
Pfizer Occupational ExposureBand (OEB):
OEB5 (control exposure to <1ug/m
3
)
Molecular Formula:
Mixture
Version: 1.3Molecular Weight:
Mixture
Page 3 of 6

You're Reading a Free Preview

Download
scribd
/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->