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A complete molecule can be duplicated in three ways. If it is solid and
three dimensional only a supernatural agency, a divine copyist, can, entering
its inner complexity, reproduce it in detail. If we prefer a natural
solution, we must imagine the molecule stretched out either in a plane
or along a line. In either case the simpler constituent molecules have
only to arrange themselves one by one on their identical partners in the
original molecule, and then become linked to each other by the absorption
of suitable quanta from radiation or from second order collisions. That such
autocatalysis is possible is indicated by recent work in Russia
and America, where the regular atomic arrays of metallic catalysts
are shown to operate like laceworkers frames on which simple organic
molecules settle to be joined into larger aggregates. A two-dimensional
reproduction of this kind is impossible, owing to the fact that the constituent
amino acids in nature are not symmetrical, but exist in right
or left hand forms. Two-dimensional reproduction would lead to mirror
image molecules, which are not found in nature. There remains then
only one dimensional reproduction. At the moment of reproduction, but
not necessarily at any other time, the molecule of the protein must be
imagined as a pseudo-linear, associating itself, element by element, with
identical groups, related by an axis instead of a plane of symmetry, and
thus preserving only right or only left handed symmetry." Bernal 1931 in
Cartwright 2012 P 9-10
the latest estimates indicate that there are some 23 000 genes in the human
genome, is suffcient to construct a human being. How does so little
information control so much behaviour? It is clear that genes must often
act as choreographers, coding the big picture while leaving the detailed steps
to be self-organized and self-assembled by physical and chemical processes.
Cartwright 2012 P 10
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"If general conditions are satisfied, the accumulation of adaptations in chemical
reaction networks can occur. These conditions are the existence of rare reactions
producing viable cores (analogous to a genotype), that sustains a molecular
periphery (analogous to a phenotype).
We conclude that only when a chemical reaction network consists of many such
viable cores, can it be evolvable. When many cores are enclosed in a compartment
there is competition between cores within the same compartment, and when there
are many compartments, there is between-compartment competition due to the
phenotypic effects of cores and their periphery at the compartment level. Acquisition
of cores by rare chemical events, and loss of cores at division, allows macromutation,
limited heredity and selectability, thus explaining how a poor mans natural selection
could have operated prior to genetic templates. This is the only demonstration to
date of a mechanism by which pre-template accumulation of adaptation could occur."
(Vasas 2012 P 1)
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"Genetic information storage and processing rely on just two polymers, DNA
and RNA, yet whether their role reflects evolutionary history or fundamental
functional constraints is currently unknown. With the use of polymerase
evolution and design, we show that genetic information can be stored in
and recovered from six alternative genetic polymers based on simple
nucleic acid architectures not found in nature [xeno-nucleic acids (XNAs)]. We
also select XNA aptamers, which bind their targets with high affinity and
specificity, demonstrating that beyond heredity, specific XNAs have the
capacity for Darwinian evolution and folding into defined structures. Thus,
heredity and evolution, two hallmarks of life, are not limited to DNA and
RNA but are likely to be emergent properties of polymers capable of
information storage." P 1
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"It has been hypothesized that the processing of visual information in primates
is accomplished by two parallel visual pathways with different spatial
and temporal characteristics. In general, the magnocellular system is most
sensitive to low spatial frequencies, has high temporal resolution and
responds quickly and transiently to moving targets. This system is thought to
be involved in such things as brightness discrimination, the perception of
motion and depth, the localization of visual stimuli in space and in the
global analysis of visual scenes". P492
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1.
Volume 8,
2.
May
3.
27
http://www.youtube.com/watch?v=vjRPla0BONA
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