?

'

2011



.
:


.

.

.

 10
''
,JAMA) 1999-1900 (2000

A
Hib-

" ,


"
Comparison of Maximum and Current Morbidity
Vaccine Preventable Diseases-- Nationwide
Maximum
Cases
Diphtheria
206,939
894,134
Measles
152,209
Mumps
256,269
Pertussis
21,269
Polio (paralytic)
57,686
Rubella
20,0001
CRS
Smallpox
48,164
Tetanus
1,5002
H. influenzae, invasive (<5 yrs)
20,0001
Total cases
Total VAERS reports
1 Estimated

2 Mortality
(Data Source: MMWR-2001)

20013 Percent
Change
2 -99.99
108 -99.99
231 -99.85
5,396 -97.89
0 -100.00
19 -99.97
2 -99.97
0 -100.00
27 -98.27
1,428 -92.86

1,610,169 7,265
0 13,526
3 Preliminary Data

-99.55
NA

"

.


:

: ,
).(ERADICATION

Polio in Israel, 1950-2003

) (


1800 50 -
IPV, 1957
OPV, 1961

19
50
19
54
19
58
19
62
19
66
19
70
19
74
19
78
19
82
19
86
19
90
19
94
19
98
20
02
,

Cases

1600
1400
1200
1000
800
600
400
200
0






) 18

Congenital Rubella Syndrome, Israel,

, ,



23
.

20
15
10

5
0

19
71
19
73
19
75
19
77
19
79
19
81
19
83
19
85
19
87
19
89
19
91
19
93
19
95
19
97
19
99
20
01
20
03
,

Cases

MMR2

MMR1

25


Rubella number of cases and rate per
100,000,1971-2010
40000

1400
Cases

Rates

35000
30000

1000
800

1973: Rubella
vaccine for
girls at 12
years

25000
20000

600

15000
1988: MMR at
15 months

400
200
0

71

74

77

80

83

86

89

10000

1994: MMR at 12
months and
booster at 6 years

92

Year

95

98

5000
01

04

07

10

Number of cases

Rate per 100,000

1200

Haemophilus influenzae b meningitis, Israel, 1981-2003

140

Improved living standards

Vaccine licensed, 1992

120
100
80

Vaccine routine,
1994

60
40
20
0

20
03

20
01

19
99

19
97

19
95

19
93

19
91

19
89

19
87

19
85

19
83

19
81

Cases

Deaths

-HIB 1994 )
5 (

HAEMOPHILUS INFLUENZAE

Incidence in Israel 1970-2010

3.00

120
1994: Hib for infants

Rates

2.50

100

2.00

80

1.50

60

1.00

40

0.50

20

0.00

70

73

76

79

82

85

88

91

Year

94

97

00

03

06

09

Number of cases

Rate per 100,000

Cases

Hepatitis A in Israel, 1990-2003

Impro in Sanitation
accine,
1.7.99

02
20

00
20

98
19

96
19

94
19

92
19

90
19

Cases

< 90%

4500
4000
3500
3000
2500
2000
1500
1000
500
0

 1951-2010

Incidence in Israel

3000

200
Rates

1952: accine for infants

Cases

175

2500
2000

125

1500

100
75

1000

Rate per 100,000

Number of cases

1955: ooster at sc ool a e

150

50

500
0

25
08

05

02

99

96

93

90

87

84

81

78

Year

75

72

69

66

63

60

57

54

51

1994
839 1700) . 50.000(

18

 :

.85-98%

.


2-15% ,
.

, .

" " )".("Herd Immunity

.
95% - 90% -
.
" .
:

,
:
,,
,
,

)

(...

..

-
" "
.
)


(

22

23

 :

.

,
.

)(ROTA,Tdap

:

) (

DTP :

:

.

 ?
NEW
ENGLAND JOURNAL OF
MEDICINE 2002
537,000
.(82%)MMR

1999
498


-
) (1988


2010
) Wakefield .(1998
2004- .
) ( "
8 .

.
.

.

) (
.

 : "


.

.
,


2011 65

, "

 :

12 .

.

::

"

.
.

""

:
, )( Hib

.

)HBV( IPV DTaP

.
: :
,
. b
.B

.

.
A
"Human right



?
?
?
?

 ?
: , ,

.

.

 -
.

10-20.

.
,

15:

300

3-5

,
.

B

.

 -
.


.


.
,
, , ' .
.

-

.
!

/ /

 ...

http://www.cdc.gov/vaccines/hcp

http://www.cispimmunize.org/pro/pdf/Vaccines-
chedule.pdf