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Scrutinizing Industry-Funded Science: The Crusade Against Conflicts of Interest

Scrutinizing Industry-Funded Science: The Crusade Against Conflicts of Interest

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This 70-page report by science journalist Ronald Bailey, published by the American Council on Science and Health in 2008, argues that there's "very little evidence that alleged conflicts of interests are significantly distorting scientific research, harming consumers and patients or misleading public policy. Most conflicts of interest activists clearly have prior strong ideological commitments against markets and corporations. They view the conflicts of interest campaign as another tool to attack an enterprise which they already despise on other grounds."
This 70-page report by science journalist Ronald Bailey, published by the American Council on Science and Health in 2008, argues that there's "very little evidence that alleged conflicts of interests are significantly distorting scientific research, harming consumers and patients or misleading public policy. Most conflicts of interest activists clearly have prior strong ideological commitments against markets and corporations. They view the conflicts of interest campaign as another tool to attack an enterprise which they already despise on other grounds."

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Categories:Types, Research, Science
Published by: American Council on Science and Health on Oct 29, 2012
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09/28/2013

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Scrutinizing Industry-Funded Science:The Crusade Against Conflicts of Interest
By Ronald Bailey
March 2008AMERICANCOUNCILONSCIENCEANDHEALTH1995 Broadway, 2nd Floor, New York, NY10023-5860Tel. (212) 362-7044
Toll Free (866) 905-2694
Fax (212) 362-4919URLs: http://www.acsh.org
http://www.HealthFactsFears.comE-mail: acsh@acsh.org
 
Robert L. Brent, M.D., Ph.D.
 A.I. duPont Hospital for ChildrenThomas Jefferson University
George E. Ehrlich, M.D., MACR, FACP,FRCP
University of Pennsylvania School of  Medicine New York University School of Medicine
Shayne C. Gad, Ph.D., DABT,ATS
Gad Consulting ServicesPast Pres., American College of Toxicology
ArthurCaplan, Ph.D.
Center for BioethicsUniversity of Pennsylvania
Thomas R. DeGregori, Ph.D.
 Department of EconomicsUniversity of Houston
Ruth Kava, Ph.D., R.D.
 Director of Nutrition American Council on Science and Health
GilbertL. Ross, M.D.
 Executive and Medical Director  American Council on Science and Health
Thomas P. Stossel, M.D.
 Brigham & Women’s Hospital HarvardMedical School
The American Council on Science and Health gratefully acknowledgesthe comments and contributions of the following individuals, whoreviewed this publication.
ACSH accepts unrestricted grants on the condition that it is solely responsible for the conduct of its researchand the dissemination of its work to the public. The organization does not perform proprietary research, nordoes it accept support from individual corporations for specific research projects. All contributions toACSH—a publicly funded organization under Section 501(c)(3) of the Internal Revenue Code—are taxdeductible.Individual copies of this report are available at a cost of $5.00. Reduced prices for 10 or more copies areavailable upon request.Copyright ©2008 by American Council on Science and Health, Inc.This book may not be reproduced in whole or in part, by mimeograph or any other means, withoutpermission.
 
TABLE OFCONTENTS
Executive Summary -------------------------------------------------------------------------------- 4Introduction ------------------------------------------------------------------------------------------ 5Scenes from the Conflicts of Interest Campaign ----------------------------------------------- 8Brief History of Funding of Scientific Research --------------------------------------------- 10The Conflict of Interest Campaign Begins ---------------------------------------------------- 12Conflict of Interest Defined --------------------------------------------------------------------- 13Industry Bias --------------------------------------------------------------------------------------- 181998 Calcium Channel Blocker COI Study --------------------------------------------------- 18The 2003 JAMAStudy --------------------------------------------------------------------------- 19Skewing the Scientific Literature --------------------------------------------------------------- 21Disclosure ------------------------------------------------------------------------------------------ 21Industrial Disinformation—The Tobacco Institute ------------------------------------------- 23The Problem of Epidemiology ------------------------------------------------------------------ 23Federal Scientific Advice ------------------------------------------------------------------------ 26The Food and Drug Administration ------------------------------------------------------------ 27The National Academies ------------------------------------------------------------------------- 32The Environmental Protection Agency -------------------------------------------------------- 33Effect of Regulatory Agency Support on Research Results -------------------------------- 37The National Institutes of Health --------------------------------------------------------------- 38Not Much Evidence that Industry/Academic Cooperation Has Undermined BiomedicalResearch -------------------------------------------------------------------------------------------- 40Public Trust ---------------------------------------------------------------------------------------- 40Patient Safety -------------------------------------------------------------------------------------- 41Cost of Medical Care ----------------------------------------------------------------------------- 42How Ethical Are Researchers Who Have No Commercial Ties? -------------------------- 44Peer Review and Disclosure --------------------------------------------------------------------- 45Register All Trials --------------------------------------------------------------------------------- 47Conclusion ----------------------------------------------------------------------------------------- 49Appendix: The Canonical Conflict of Interest Cases ---------------------------------------- 51About the Author/Disclosure -------------------------------------------------------------------- 56References ----------------------------------------------------------------------------------------- 58

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