Module Name Week

: REPRODUCTIVE SYSTEM (MODULE 16) : : 2nd WEEK

MICROBIOLOGY 1) Bleeding should be avoided because__________ may mask spirochetes as they are almost same size. A. rbcs B. wbcs. C. platelets D. lymphocyte

2) Fluorescent treponemal [FTA] test _________earlier because it can detect IgM Anti treponemal antibodies. A. positive B. negative. C. no changes. D. None of the above

3) All the following are common properties of herpes virus , Except: A) ablility to cause latent infections B) Very succesfull parasite because high raio of clinical to subclinical infection C) Double stranded DNA D) Produce giants cells 4) Haemophilus ducreyi is as following, EXCEPT: A. Gram Negative Rods B. Recuires Factor X , not factor V C. Cultured on Chocholate Agar iso-Vilatex + Vancomycin D. Incubated aerobically only E. Treat by Ceftriaxone(IV) or co-trimoxazole or erythromycin

5) Following are true for the Serological test for syphilis , EXCEPT: A) for diagnosis B) for monitoring treatment C) follow up cases D) for test the severity

6) Which of the following is TRUE about Rapid Plasma Reagin test (RPR) : A) performed on glass slide with ceramic ring B) Antigen is emulisified in special buffered saline then mixed with patients heat inactivated serum on the ring C) performed on unheated patients serum or plasma mixed with carbon containing cardiolipin antigen D) machine rotate for Four minutes

7) The following is Characteristic of Treponema pallidum (spirochetes) , EXCEPT: A) have Cork-screw for bending movement. B) Sharp C) Regular space D) Large

8) T.pallidum is Reiter strain had been culture aerobically and composed of serum albumin, amino acids, vitamin and minerals: A) True B) False

9) The following is true for Secondary stage of acquired syphilis , EXCEPT : A) non itchy maculo-papular rash anywhere in the body B) Hard chancre C) present of moist pale papules (Condylomalata) in moist area D) mucous patches occurs mainly in oropharynx

10) Which of the following is False regarding serological test for syphilis : A) Primary stage -cardiolipin Ab test ( NEGATIVE ) , Treponemal Ab test ( Positive) B) Secondary stage - cardiolipin Ab test ( Positive ) , Treponemal Ab test (Positive) C) Latent stage - cardiolipin Ab test (Positive) , Treponemal Ab test (Positive) D)Late stage (Serum ) - cardiolipin Ab test (Positive) , Treponemal Ab test ( Negative)

11) Treatment for Syphilis , EXCEPT: A) benzathine penicillin B) Acyclovir C) cephalosporins D) Tetracycline

12) All the following is False about treatment of Mycoplasm , EXCEPT: A) Tetracycline B) erythromycin C) Cephalosporin D) Penicillin

13) Which of the following is true about mycoplasma: A) Mycoplasma hominis cause ectopic pregnancy in female B) Smallest bacteria with rigid cell wall C) Susceptible to penicillin D) Ureaplasma urealyticum are associated with non-gonococcal urethritis in male

14) All are the complications of reiter's syndrome caused by chlamydia trachomatis EXCEPT a. urethritis b. conjuctivitis c. pyelonephritis d. uveitis e. polyarthritis

15) the following are the lab diagnosis c thracomatis EXCEPT: a) isolation in Mccoy cells b) antigen detection in ELISA c) cytologic examination using smear stained with giemsa stain d) detection high titre of IGM shows recent infection

16) All are true about Lymphogranuloma venereum (LGV) , EXCEPT: A) it is a acute Sexually Transmitted Disease (STD) B) begin with genital ulcer followed by lymphadenopathy of regional LN C) Rupture of enlarged buboes forming a Fistula D) Untreated LGV lead to Elephantiasis to block lymphatic drainage

17) which of the following is false about Chlamydial infections: A) 35%-50% of non-gonococcal urethritis caused by C. trachomatis B) most of the woman is symptomatic and men is asymptomatic C) Complication of untreated infection may causes infertility, salphingitis,ectopic pregnancy D) Genital tract cause by serotype D-K while LGV is by serotype L1 ,L2 ,L3

18) HSV-1 become latent in..... A) lumbar ganglia B) trigeminal ganglia C) sacral ganglia D) thoracic ganglia

19) Laboratory Diagnosis of Papilloma viruse, EXCEPT : A) Do not grow in cell culture B) Direct immunofluorescence C) PCR & N.A. probes for detection HPV genomes in tissues

20) All the following is the clinical finding in HSV-1 , EXCEPT : A) Acute gingivostomatitis , Keratoconjuctivitis, Aseptic Meninggitis B) Disseminated infection ,Neonatal herpes, Herpes labialis C) Herpetic Whitlow, Encephalitis, Acute ginggiostomatitis D) Neonatal herpes, Genital Herpes, Aseptic Menggitis

21) What is the drug use for treatment of HPV : A) Tetracycline B) Acyclovir C) Erythromycin D) Penicillin

22) Clinical features of Papilloma viruses : A)Rash B)Ulcer C) Cheese appearance D) Wart

23) Which of the following is true about HSV-2? A) It cause the lesions above the waist B) It become latent in trigeminal ganglia C) It is transmitted through birth canal D) It cause Encephalitis

PATHOLOGY 24) All of the following are the clinical pictures of the endometriosis EXCEPT: A. severe menorrhagia B. Infertility C. Acute Abdomen D. Dyscasia

25) Which of the following type of endometrial hyperplasia has the highest risk for endometrial carcinoma? A. Simple endometrial hyperplasia B. Complex endometrial hyperplasia with polypoidal endometrium C. Complex endometrial hyperplasia with atypia

26) Which of the following is true for the Cause of Endometrial Hyperplasia: A) Prolong unopposed estrogen stimulation B) Obesity C) Nulliparity D) Anovulatory cycles E) All the above

27) Which of the following is the Microscopic features of Simple Endometrial Hyperplasia : A) endometrial gland increase , cystically dilated & swiss chess appearance B) Crowded gland & branching while stroma is scanty C) crowded Gland & irregular lining epithelial show nuclear Atypia

28) All the following are common site of Endomertiosis ,EXCEPT : A) Peritoneal cavity B) ovary & uterine ligament C) Fallopian tube D) Douglass pouch 29) Which of the following is TRUE about Endometriosis gross & microscopic : A) Gross : Dark brown nodules , Microscop : Endometrial stroma B) Gross : Chocolate Cyst , C) Gross : Red brown , Microscop : Hemosiderin pigmentation Microscop : Tortures Artery

D) Gross: Grayish white nodules, Microscop : Endometrial glands

30) All of the following are FALSE regarding prognosis of endometrial tumors EXCEPT: a) Stage I tumor is limited to the fallopian tube and uterus and its probability is 90% b) Stage II - tumor involves the cervix and its probability is 55% c) Stage III tumor extending outside the uterus but not outside the pelvis and its probability is 30% d) Stage IV tumor extending outside the pelvic and involve local spread and its probability is 15%

31) Choose the CORRECT answer about clinical effects of uterine leimyoma I All are asymptomatic II Submucosal leiomyoma may cause abnormal uterine bleeding III Pedunculated submucosal fibroids may twist and become necrotic IV leiomyoma do not transform into leiomyosarcoma. a) I and II b) II and IV c) I and IV d) III and IV

32) Which of the following is TRUE about Endometrial carcinoma , EXCEPT A) caused by prolong Estrogen stimulation of endometrium B) Obesity & Estrogen replacement therapy is the Risk factor C) Exophytic polypoidal mass extend into myometrium D) Hematogenous spread to distant sites especially lung.

33) All the following are FALSE regarding Type 2 endometrial carcinoma (papillary serous carcinoma), EXCEPT: A) most common B) occurs in young women C) has relation with hyperestrenism D) worse prognosis

34) Which of the following is False about Uterine leimyoma : A) has risk of malignant transformation B) most common benign tumours C) may undergo Degeneration, Dystrophic calcification & hyalinization D)responsive to Estrogen 35) Which of the following is False about Luteal cysts: A) present in Ovary lined by luteal cells B) Ruptured , produce External Hemorrhage and acute abdomen C) Corpus hemorrhagicium sealed immediately

36) All the following is False regarding Polycystic ovaries , EXCEPT : A) Present of corpura lutea microscopically B) Decrease production of Androgen C) Clinical features shown Oligomenorrhea , hirsutism, obesity , & infertility D) Small ovaries

37) The following tumors arise from surface epithelium-stromal tumors EXCEPT: a. Serous tumors b. Mucinous tumors c. Endometriod tumors d. Thecoma

38) the followings are characteristics of serous borderline tumor EXCEPT a. stratification of epithelial cells b. complex papillae c.moderate atypia of cells d. presence of psammoma bodies

39) The following are the similarities of serous borderline tumors and serous cystadenoma EXCEPT... a)atypia of cella b)complex papillae c)proliferation of epithelial cells d)invasion of basement membrane

40) Which of the following is False about Mucinous Tumors : A) 30 % are borderline tumors B) Endocervicallike & Interstinal-like type is the histological type of Benign mucinous cystadenomas C) Rupture or metastasis lead to Pseudomyxoma Peritonei. D) Grossly shown large Cysts , multilocular contain mucinous fluid.

41) What is ascitis? a)accumulation of fluid in the thorax b)its one of the clinical picture of granulosa-theca cell tumor c)accumulation of mucinous fliud in ovary d)accumulation of fluid in peritoneal cavity

42) All these are germ cell tumors , EXCEPT : A) Dysgerminoma B) Yolk sac tumor (endodermal sinus tumor) C) Brenners tumors D) Choriocarcinoma

43) Which of the following are more common among younger women? I. granulosa-theca cell tumor II. mature cystic teratoma III. dysgerminoma IV. immature solid teratoma

A. I & II B. IV only C. II & IV D. II, III & IV

44) Woman, 36 year old presented with vaginal bleeding and endometrial Hyperplasia. Ultrasound was normal, pop smear was normal. What is the diagnosis likely to be?? A) Mature cyst-teratoma B) Granulosa theca tumor C) adenomyosis D) leiomyoma

45) Krukenbergs tumor can be found in : A) Germ-cell tumors B) Serous tumors C) metastatic tumors D) Fibrothecoma

46) Which one of this teratoma is not malignant ? A) monodermal teratoma B) mature cystic teratoma C) immature solid teratoma D) teratoma with malignant transformation

PARASITOLOGY

47) Regarding trichomonas vaginalis,all of the following are correct, EXCEPT: a)having a single vesicular nucleus b)undulating membrane is supported by costa c)anteriorly there is prominant cytosome d)reproduce assexually by binary fision

48) Which is False regarding the method of infection by trophozoite? A) Kissing B) During birth, transmitted from mother to infants. C) Sexual intercourse D) Contaminated underwares, toilet seats & towels.

49) All are true abut the Clinical picture of trophozoite , except: A)Severe vulva & vaginal pruritis show vaginal discharge in female B)Infection in male is symptomatic or persistent urethritis & prostatitis C) In female, it show seropurulent & frothy

50) Which drug used as treatment for trophozoite ? A) Acyclovir B) Tinidazole C) Augmentin D) Clotrimazole E) A & C F) B & D

51) Which of the following is False about diagnosis in trophozoite vaginalis: A) It present in sedimented urine and vaginal secretion in female B) Care must be taken to prevent faecal contamination C) Culture is more valuable D) If wet smear cannot be examine immediately, sample should be dried, fixed, use Gram stain

ANATOMY 52) Muscles related to base of breast are all of these EXCEPT: A) pectoralis major B) pectoralis minor C) serratus anterior D) external oblique

53) Invasion of lactiferous sinus leads to retracted nipple A) True B) False 54) Those are the arteries that supply the breast EXCEPT: a) axillary artery b) lateral thoracic artery c) acromial branch of thoracoacromial artery d) pectoral branch of thoracoacromial artery

55) Which of the following is the lymphatic drainage of the axillary tail? a) internal mammary lymph nodes b) anterior abdominal wall lymph nodes c) posterior group of the axillary lymph nodes d) pectoral group of the axillary lymph nodes

56) Occurs when a remnant of mammary line develops into complete breast. Which type abnormality is related to this statement?? A) Polythelia B) Polymastia C) Retracted nipple / inverted nipple D) Gynecomastia

57) All of the following are true regarding the mammary gland EXCEPT: a) the base rest upon deep fascia covering pectoralis major, serratus anterior and external oblique muscle b) axillary tail extends up and laterally and enter the axilla c) the base of the cone is nipple that is surrounded by areola d) the breast is separated from underlying muscles by loose areolar tissue,superficial to deep fascia called retromammary space

58)- When normal suckling of and infant cannot be take place and the nipple is prone to infection, it is concerning to: a) polythelia b) retracted nipple or inverted nipple c) micromastia d) macromastia

PHYSIOLOGY

59) All are the result, when there is no oestrogen are secreted in menopause women EXCEPT: A) osteoblastic activity decrease B) bone matrix decrease C ) deposition of bone calcium and phosphate increase D) deposition of bone calcium and phosphate decrease

60) Whish of the following is not related to Hypogonadism after Puberty? A) Vagina small in size B) cause by removed fully developed ovaries C) Prolong growth of long bone due to epiphyses do not unite with shafts of long bone D) Breast become atrophy & pendulous

61) All the following is the effect of Progesterone on uterus, EXCEPT: A) Increase uterine contraction to prevent expulsion of the implanted ovum B) Promote secretory changes in the uterine endometrium C) Cervical mucus become thicker D) Prepare uterus for implantation of the fertilized ovum

62) Which part of genital organ is more resistant to trauma & infection due to functional effect of estrogen? A) Fallopian tube B) Uterus C) Vagina

63) Which of the following is true about Menopause? A) Less secretion of FSH & LH B) The cycle cease & female sex hormone diminish regularly C) Loss of estrogen causes hot flashes D) Occurs at age 30-40 years age

64) All the following is False about function of plancenta , EXCEPT: A) Diffusion of foodstuff from fetus blood to mother blood B) Fetal excrete it excretion product by himself, not by mother. C) Only diffusion of Oxygen occurs at placenta membrane D) Relaxin is secreted by placenta during pregnancy

65) Which of the following is False about function of Human chorionic somatomammotropin? A) Complete development of breast B) Lactogenic activity like prolactin C) Increase utilization of glucose by mother, causing low quantity glucose for fetus D) Sodium, potassium, calcium retention.

66) Which of the following is False about mammary gland & lactation? A) Oxytocin cause milk ejection B) During childhood, mammary gland is surrounded by large amount of Connective tissue C) Milk is secreted by Prolactin hormone & Chorionic somatomammotropin D) Estrogens cause proliferation of ducts, fat deposition, stroma growth & nipples development.

67) All the following is False about other maternal hormone, EXCEPT: A) Basal glucagon do not change significantly B) Aldosterone cause Negative balance during pregnancy C) Total plasma thyroid hormone is decline D) Calcium absorption from diet is decrease

68) Why maternal growth hormone in anterior pituitary gland decreased ? A) To maintain high total plasma volume and build extracellular fluid of fetus B) Due to decrease secretion of progesterone, estrogen, & inhibin from corpus luteum & placenta C) its anabolic function is carried out by human chorionic somatomammotropin & placenta growth hormone variant. D) Increase maternal levels of active metabolite of Vitamin D.