Description

High-throughput trace melamine analysis in complex mixturesw
Guangming Huang,a Zheng Ouyang*b and R. Graham Cooks*a
Received (in Cambridge, UK) 15th October 2008, Accepted 11th November 2008
First published as an Advance Article on the web 1st December 2008
DOI: 10.1039/b818059h
Ambient ionization using a low-temperature plasma (LTP)
probe combined with tandem mass spectrometry (MS/MS)
allows detection and quantitation of melamine in milk powder,
whole milk and other products at levels down to low ppb in
analysis times of a few tens of seconds.
samples in the ambient environment without any prior sample
preparation. LTP ionization is among a number of new
ambient ionization methods14–20 that include desorption
electrospray ionization (DESI),14–16 DART,21 electrospray
laser desorption ionization,22–24 desorption atmospheric pre-