Evidence for S.Mutans as the major bacterial etiologic factor in human dentalcaries
It can almost always be isolated from plaque.
Most carious lesions have >10% S. Mutans.
Most non-infected areas are non-carious.
Longitudinal studies show S. Mutans precedesdevelopment of dental caries.There are studies showing that children who do notbecome infected in the first 3 years of life,appearto remain uninfected for several years, possiblyuntil a new opportunity for colonization occursupon eruption of the secondary dentition.