CENTRAL ANALGETICS (analgesics) -- Chemistry & Pharmacology of Drugs -- Daniel Lednicer (1982)

 
 
 
 
 
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ISBN: 0-471-08314-3 (0471083143)

CENTRAL ANALGETICS -- Chemistry & Pharmacology of Drugs (vol. 1)

The 1982 text "Central Analgetics" is another great contribution from Daniel Lednicer to the organic & medicinal chemistry community. If you enjoyed Lednicer's "The Organic Chemistry of Drug Synthesis" series, you will also enjoy this comprehensive review of the organic chemistry of opioid synthesis & their structure-activity relationships.
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FROM THE PREFACE:

Chemistry and Pharmacology of Drugs is a series of books intended to allow scientists involved in drug development to become familiar with specific therapeutic areas by consulting a single volume devoted specifically to that area.

A description of the organic and medicinal chemistry of central analgetics forms the last chapter of this book. In this section, Lednicer describe in some detail the chemistry and structure activity relationships of the more important classes of opioids developed to date. The discussion goes beyond agents used in the clinic in order to illustrate salient points on the evolving concept of the SAR of these agents. A critical review of SAR, as used to carry out receptor mapping in the opioid series, has been included.
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CHAPTERS:

(1) PAIN PATHWAYS: POTENTIAL SITES FOR ANALGETIC ACTION -- J. Scott Mohrland

(2) PHARMACOLOGICAL ALTERATION OF PAIN: THE DISCOVERY AND EVALUATION OF ANALGETICS IN ANIMALS -- Philip F. VonVoigtlander

(3) THE POTENTIAL OF CENTRALLY ACTING REGULATORY PEPTIDES AS ANALGETICS -- John S. Motley

(4) MEDICINAL CHEMISTRY OF CENTRAL ANALGETICS -- Daniel Lednicer

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02/09/2009

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****IMPORTANT: if anybody out there has a digital ebook version (in .PDF or .DJVU or another format) of any of the following opioid/analgesic medicinal chemistry texts, please let me know by sending a message or uploading the document to scribd: (1) Title: "Opioid Analgesics: Chemistry and Receptors" Authors: Alan F. Casy & Robert T. Parfitt 540 pages Year Published: 1986 Language: English ISBN-10: 0306421305 ISBN-13: 978-0306421303 (2) Title: "Analgetics (Medicinal Chemistry Monograph Series, Volume 5)" Editor: George deStevens Publisher: Academic Press Year Published: 1965 Library of Congress Catalog Card No.: 65-15524 **Note: while I currently own both books in PRINT format, it would be a great help (& time saver) if I could find a digital version that has already been scanned & digitized. ****I can offer a generous FINDER'S FEE to anyone who provides a digital version of either of these books. Please contact me if you have any additional information. Thank you. --JTJDP

03 / 26 / 2009