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  • Philadelphia Chromosom

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    Mutiara Syafitri
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    71 views1 page

    Philadelphia Chromosom

    Uploaded by

    Mutiara Syafitri

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    Kromosom

    Philadelphia atau translokasi Philadelphia adalah abnormalitas kromosomal spesifik yang berkaitan dengan leukemia granulositik kronik (LGK). Kromosom Philadelphia merupakan hasil dari translokasi resiprokal antara kromosom 9 dan 22 (t(9;22)(q34;q11)). Adanya translokasi tersebut merupakan hasil tes yang sangat sensitif untuk LGK, 95% pasien LGK memiliki kelainan ini.

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