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Outsourcing Drug Discovery: Your service partner from discovery through development

Outsourcing Drug Discovery: Your service partner from discovery through development

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EMD Millipore is your premier service provider for confidently advancing your drug pipeline from discovery to market. We extend your capabilities by combining our scientific knowledge, regulatory expertise and flexibility, with the trusted, relevant information required for your drug
discovery and development needs.
EMD Millipore is your premier service provider for confidently advancing your drug pipeline from discovery to market. We extend your capabilities by combining our scientific knowledge, regulatory expertise and flexibility, with the trusted, relevant information required for your drug
discovery and development needs.

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Categories:Types, Research
Published by: EMD Millipore Bioscience on Jan 18, 2013
Copyright:Attribution Non-commercial

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01/18/2013

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EMD Millipore is a division o Merck KGaA, Darmstadt, Germany
Trusted expertisethrough every phase.
Simpliy your outsourcing decisions –choose EMD Millipore as your service partnerrom discovery through development.
 
Featuring
As a leading innovator in ow cytometry technologies and services, EMD Milliporeunderstands the power o in-depth cell analysis or research and pharmaceuticaldevelopment. We combine our custom assay development, assay validation, and sampleprocessing capabilities with the most clinically established platorm, the BD FACSCanto™ II.Our service portolio includes immunophenotyping, detection o intracellular andextracellular markers, antigen binding assays and more.
Benefts:
•
 A powerul, exible analytical tool or drug efcacy measurement
•
Scientifc expertise rom optimized sample preservation to robust validation
•
Extensive data interpretation and processing
Learn more atwww.emdmillipore.com/biomarkerservices
UbiquitinProfler™ Service removes the complexity o ubiquitin pathway drugdevelopment, and is the only service that enables you to explore the completeubiquitination cascade, including E3 ligase activity.
Benefts:
•
 Functional screening and profling assays or an expanding panel o E3 ligase cascadesto screen and profle inhibitors and enhancers
•
Cascades consists o E1, E2 and E3 enzymes and biologically relevant substrates
•
Led by the same experts who have run KinaseProfler™ services or over 10 yearsAlso available: related E1, E2, E3 and substrate products or unctional assays
Learn more atwww.emdmillipore.com/ubiquitin
UbiquitinProfler™ ServicesNEW! Flow Cytometry Assay Services
 
Pre-ClinicalHTS & Lead DiscoveryPhase 1Phase 2Phase 3LaunchTarget Validation
Our service expertise spans the drug discovery process.
Screening and ProflingServices
Biochemical and cell-basedunctional assays or kinase, GPCR,ion channel and ubiquitinationtargets ● Proling services ●Customized solutions throughassay development.
In Vitro 
Toxicity Studies
Industry-leading, unctionalproling against 125 GPCR, kinase,phosphatase and ion channel targets.
Cell-Based Assay Services
GPCRProler® and IonChannelProler™ services integrate EMD Millipore’s stable GPCR and ion channel cell line products into unctional assays or small and large moleculepotency and selectivity proling ● GxP-compliant services or testing neutralizing antibody assays during tiered immunogenicity testing and in potency and stability testingo biotherapeutics.
Biomarker Analysis Services
Protein and nucleic acid biomarker analysis ● RIA, ELISA, Luminex® xMAP® technology, electrochemiluminescence (ECL), Gyrolab® and fow cytometry services using the EMD Millipore portolio o assays or commerciallyavailable kits rom any vendor ● Transer, develop and validate custom assays to meet your requirements ● Exploratory and GxP nucleic acid analysis using the latest qPCR and Pyrosequencing® instrumentation.
Biopharmaceutical Analysis Services
Experienced development and perormance o cell-based potency and ligand binding assays or impurity testing, batchrelease and testing o stability samples ● Claim compliance to GMP or regulatory submission or as a non-regulatory studyunder the same high quality standards ● Wide range o cell-based assays (e.g. ADCC, cell prolieration, receptor binding)and ligand binding techniques including ELISA/RIA, Luminex® xMAP® Technology, surace plasmon resonance (Biacore™), ECLand immunoblotting.
Pharmacokinetic Services
Industry-leading experience in the development and validation o PK/TK assays or the measurement o large moleculesand peptides ● Scalable solutions to meet your specic needs, rom routine sample analysis through to ull-service assaydevelopment and validation.
Immunogenicity Services
Adhering to current FDA and EMA guidelines and AAPS white papers, we ollow a stepwise approach to measure anti-drugantibody responses using ELISA/RIA, surace plasmon resonance, GyroLab®, ECL, DELFIA® and Nab analysis using cell-basedassays ● We transer, develop and validate methods and evaluate several platorms to ensure optimal data quality ● Withunsurpassed industry experience, EMD Millipore provides the technical expertise, quality assurance and peace o mindthat are essential when considering a partner or research, preclinical through to clinical regulated assay development andsample analysis on any scale.
www.emdmillipore.com/discdev
From discovery throughdevelopment.
 
EMD Millipore is your premier service provider orcondently advancing your drug pipeline rom discoveryto market. We extend your capabilities by combining ourscientic knowledge, regulatory expertise and fexibility,with the trusted, relevant inormation required or your drugdiscovery and development needs.

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