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biotransformation of drugs

biotransformation of drugs

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Published by Zaigham Hammad

metabolism of drugs

metabolism of drugs

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Categories:Types, School Work
Published by: Zaigham Hammad on Jan 31, 2013
Copyright:Attribution Non-commercial

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09/17/2013

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Biotransformation(Metabolism) of Drugs
 
 A.General properties
1.Biotransformation is a major mechanism fo
drugelimination
;
Results of biotransformation:
 –
Production of metabolites that are more polar thanthe parent drug
 –
usually terminates the pharmacologic action of theparent drug
 –
 After phase I reactions, similar or differentpharmacologic activity, or toxicologic activity.
 
Results of biotransformation

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