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East Africa has become the third most im-portant growing region in the world for Ar-temisinin, the active ingredient in the mosteffective antimalarial, the United Nations(UN) reported in January.
Until recently, almost all
Artemisia annua
plants, native to Asia, were grown in Chinaand Vietnam, but in 2002 a handful of Kenyanfarmers contracted with the local company Botanical Extracts EPZ Ltd. (BEEPZ) to plant40 hectares of the plant.
Artemesia annua
cultivation now supportsat least 40,000 smallholder farmers growing4,000 hectares of the crop in Kenya, Tanzaniaand Uganda.Commercialization of the plant was madepossible by grants from Britain’s Departmentfor International Development (DfID) andthe Swiss pharmaceutical company Novartis.BEEPZ pays between $550 and $600 per met-ric ton. One hectare can produce up to twometric tons of dry leaves.Cultivation of the plant in Africa is consid-ered critical to ensuring a less expensive supply of the drug that has taken over from the olderquinine-based medicines no longer consideredeffective against several forms of malaria.According to the UN
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the Kenyan govern-ment buys about 17 million doses of Artemis-inin drugs annually at a cost of $24 million forfree use at government clinics. At private phar-macies, the cost per dose ranges from about$5.50 to $8.20.In 2006, BEEPZ paid out $1.7 million tofarmers. e company completed an Artemis-inin extraction plant in 2007 and now suppliesNovartis with enough Artemisinin for morethan 22 million doses of the drug.
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EAST AFRICA NOWA KEY SUPPLIER OFARTEMISININ
Workers cultivate Artemisia annua plants inTanzania
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NOVO NORDISK TO SUPPLY AFFECTEDCHILDREN WITH FREE INSULIN
Danish bio-pharmaceutical company NovoNordisk announced in December that itwould provide diabetes care and free insulinto 10,000 children in the Democratic Repub-lic of Congo, Guinea-Conakry, Tanzania andUganda beginning in 2009.
e five-year program, called “Changingthe Future for Children with Diabetes,” will bebased on a hub-and-spoke concept with satel-lite centers around existing hospitals and clin-ics. With an estimated cost of $25 million, it isaimed at building sustainable solutions for im-proving availability, accessibility, affordability and quality of diabetes care for children withtype 1 diabetes.An estimated 38,000 African children havetype 1 diabetes, the majority of whom diewithin a year of diagnosis due to lack of ac-cess to insulin. While still relatively rare inAfrica, type 1 diabetes is on the rise due toincreased urbanization and changes in dietary and exercise habits. “e premature death of achild caused by lack of insulin is unacceptable,when a life-saving solution is available,” saidDr. Jean Claude Mbanya, President-elect of the International Diabetes Foundation (IDF).“We must work together across borders tokeep these children from dying. is is why Iwelcome this new program being launched by Novo Nordisk.”e bio-pharmaceutical company aims tocollaborate with as many local partners as pos-sible, including governments and diabetes as-sociations, and regional chapters of the IDF. Inaddition to providing free insulin, it will focuson helping to improve the health care infra-structure of the host countries.“is project will not only provide insu-lin free of charge to an extremely vulnerablegroup, it is also designed to build long-termsolutions for insulin distribution and sustain-able diabetes care for all people with diabetesin the world’s poorest countries,” said Mr. LarsRebien Sǿrensen, President and CEO of NovoNordisk A/S.Novo Nordisk hopes to expand the programbeyond the initial four participating coun-tries.
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GLOBAL PARTNERS BEGIN FINAL PUSHTO ERADICATE PARASITE
e Bill & Melinda Gates Foundation andBritain’s Department for International De- velopment (DfID) announced in Decemberthat they were jointly committing $55 mil-lion to the effort led by the Carter Center tofinally eradicate Guinea worm disease.
“Guinea worm is poised to be the seconddisease eradicated from Earth, ending need-less suffering for millions of people from onethe world’s oldest and most horrific afflic-tions,” said former US President Jimmy Carter,whose Atlanta-based center has been workingfor more than two decades on the eradicationeffort.He said that cases of Guinea worm diseasereached an all-time low in 2008 with less than5,000 cases reported in six African nations,down from 3.5 million cases in 1986 in 20 na-tions in Africa and Asia.In the first 10 months of 2008 only 4,410incidents of Guinea worm were reported inEthiopia, Ghana, Mali, Sudan, Niger and Ni-geria. It is already suspected that the last caseshave been reported from Nigeria and Niger,according to the Carter Center.e Gates Foundation is contributing $40million as a challenge grant to the Carter Cen-ter. It includes an outright contribution of $8million and encourages other donor organiza-tions and individuals to provide an additional$32 million that the Gates Foundation willmatch one-to-one. e British governmenthas pledged about $15 million. e funds willbe shared equally between the Carter Centerand the World Health Organization (WHO).Guinea worm disease will be the first diseaseto be wiped out without a vaccine or medicine.Interventions include health education, freecloth filter distribution and larvicide applica-tions. To date, about $225 million has been in- vested in the eradication effort.“e drive to eradicate Guinea worm dis-ease is one of the world’s most impressiveglobal health success stories,” said Dr. ReginaRabinovich, Director of Infectious DiseasesDevelopment at the Gates Foundation.
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