Professional Documents
Culture Documents
F 50, vulva
VULVAR INTRAEPITHELIAL NEOPLASIA (VIN) Dysplasia characterized by epithelial cells with enlarged and hyperchromatic nuclei, high mitotic activity, and dyskeratosis. May involve the skin appendages in 50% of cases. Abnormal mitoses consistently present in VIN 2 and 3 VIN I Dysplasia in lower 1/3 of epithelium VIN II Dysplasia in 1/2 to 2/3 of epithelium VIN III Dysplasia greater than 2/3 of epithelium Carcinoma in situ used if there is full thickness change