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Shock n Sepsis

Shock n Sepsis

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Published by rajan kumar
shock,basic pathophysiology,types,management. sepsis in surgical icu,common cause of mortality.management of sepsis.
shock,basic pathophysiology,types,management. sepsis in surgical icu,common cause of mortality.management of sepsis.

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Categories:Types, Research
Published by: rajan kumar on Feb 18, 2009
Copyright:Traditional Copyright: All rights reserved

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01/28/2013

original

 
 
SHOCK SHOCK 
“A rude unhingingof the machinery of life”
 
- Gross
-:
 
RAJAN
 
 
DefinitionDefinition
Shock is a systemic state of lowShock is a systemic state of lowtissue perfusion, which istissue perfusion, which isinadequate for normal cellularinadequate for normal cellularrespiration. With insufficientrespiration. With insufficientdelivery of oxygen and glucose,delivery of oxygen and glucose,cells switch from aerobic tocells switch from aerobic toanaerobic metabolism. If anaerobic metabolism. If perfusion is not restored in aperfusion is not restored in atimely fashion, cell death ensues.timely fashion, cell death ensues.
 
 
PathophysiologyPa
 
thophysiology
Physiologic response to hypovolemiaPhysiologic response to hypovolemiadirected at preservation of directed at preservation of perfusion to vital organsperfusion to vital organs-Increase cardiac contractility &-Increase cardiac contractility &peripheralperipheralvascular tone viavascular tone viaANSANS-Hormonal response to preserve-Hormonal response to preservesalt &salt &waterwater -
 
-Chane in local micro circulation to

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