Frustrated with current T cell assays? Take control with asingle assay that gives you all the information you need.Discover which individual T cells express FOXP3, TNF-
, orother effector genes—without staining or cell sorting.Starting with a single-cell suspension, GigaMune® TELS™ (TCR
-Effector Linkage Sequencing) uses uniquemicrofluidics and molecular techniques to physically link Tcell variable regions to effector genes expressed withinmillions of individual T cells in a sample. By sequencingTCR
-effector linkage products, GigaMune® TELS™ givesyou simultaneous, quantitative measurements of T cellclonal identity and effector gene activity. Never has asingle assay combined accurate measures of T cell identity,clonality, expansion, and function. Let GigaMune® TELS™ revolutionize your understanding of the T cell response.
T cell identity, function, and abundance
in a single assay
Autoimmune diseasesTransplant rejection and toleranceImmune response to malignancyCancer immunotherapyAdoptive T cell therapyAsthma and allergyInflammatory conditionsInfectious diseasesVaccine development and efficacyGlobal immune function and health••••••••••
Millions of single cells processed per hourDetect rare and ultra-rare T cell clones from peripheralblood
Massively parallel amplification of transcripts produced bysingle cellsClassify T cells based on expression of functional effectorgenes such as transcription factorsMultiplexed measurements of TCR
CDR3 sequence andeffector gene transcriptsLearn clonal identity, abundance, and function from thesame sampleHigh-quality sequence of TCR
CDR3 regionsQuantify and distinguish multiple clonotypes with specificeffector functionsAccurate measurements of clonal abundanceMake objective, quantitative comparisons of clonalexpansion across samplesPowerful web-based software suite for data storage,processing, and analysis in the cloudTrack abundance and expression profiles of clones acrosssamples, with statistical analysis
A REVOLUTION IN FUNCTIONAL T CELL ANALYSIS
GigaGen laboratory and professional servicesGet reproducible results quickly with no startup costs ortraining time required
GigaMune® TELS™ is For Research Use Only. Not for use in diagnostic procedures.