Radiology (dra Bandong
Bone tumors
19 July 08
\u2022Bone tumors can be divided into primary and
secondary
\u2022Secondary tumors can be further subdivided into:
o
Metastatic tumors
o
Tumors resulting from contagious
spread of adjacent soft tissue
neoplasm
o
Tumors representing malignant
transformation of the preexisting
benign lesion
Metastatic disease
\u2022Most malignant tumor found in the bone
\u2022Predominant in 2 age group:
-adult over 40 yr. old and children In the 1st
decade of life
\u2022Multifocality and predilection for hematopietic
marrow sites in axial skeleton( vertebrae, pelvis,
ribs, cranium) and the proximal long bone
\u2022Metastases to long bones distal to elbows and
knees are unusual
Most common malignancies producing
skeletal metastases:
Adults
\u2022More than 75%
originates from the
carcinomas of prostate,
breast, kidney and lungs
\u2022Also common are
metastases form the
thyroid and colon cancer
\u2022melanoma
Children
\u2022neuroblastoma
\u2022rhabdomyosarcoma
\u2022retinoblastoma
Radiologic appearance of the metastatic tumor
\u2022purely lytic
- kidney, lungs, colon, melanoma
\u2022purely blastic
- prostate and breast carcinoma
\u2022mixed lytic and blastic
- most common appearance
Primary bone tumors
\u2022predominant appearance in the 1st 3 decades of
life
\u2022the most common sites include distal femur and
proximal tibia
\u2022benign tumors are more common than malignant
one
\u2022the most common benign tumors are
osteochondroma, non-ossfying fibroma and
enchondroma
\u2022among the primary malignant tumors:
- osteosarcoma and multiple myeloma
have highest incidence followed by
chondrosarcoma and Ewing\u2019s
sarcoma
AGE 0-10
Most common benign
lesion
\u2022simple bone cyst
\u2022eosinophilic granuloma
Most common malignant
tumor
\u2022Ewing sarcoma
\u2022Leukemic involvement
\u2022Metastatic
neuroblastoma
AGE 10-20
Mika maQ
1 of 15
Radiology \u2013 GI Radiology by Dra Bandong
Page2 of 15
Most Benign lesion
\u2022Non ossifying fibroma
\u2022Simple bone cyst
\u2022Aneurysmal bone cyst
\u2022Osteochondroma
(exostosis)
\u2022Osteoblastoma
\u2022Chondroblastoma
\u2022Chondromyxiod fibroma
Most common malignant
tumor
\u2022Osteosarcoma
\u2022Ewing\u2019s sarcoma
\u2022adamantinoma
AGE 30 and above
Most benign lesion
\u2022osteoma
Most malignant tumors
\u2022metastatic tumor
\u2022myeloma
\u2022leukemic involvement
\u2022chondrosarcoma
\u2022osteosarcoma (Paget\u2019s
associated)
\u2022MFH
\u2022Chordoma
Site of long bone Involvement:
Giant Cell Tumor
Radiology \u2013 GI Radiology by Dra Bandong
Page3 of 15
Metaphyseal intramedullary lesions
- osteosarcoma is
usually centered in the
metaphysis
-chondrosarcoma and
fibrosarcoma often
present as
metaphyseal lesions
- osteosarcoma, enchondroma, fibrous dysplasia,
simple bone cyst and aneurysmal bone cyst are
common in this location.
Osteosarcoma
Chondrosarcoma
- typical chondroid
matrix calcification
Metaphyseal lesions centered in the cortex
of 00
Bone Tumors
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| Category: | Uncategorized. |
| Rating: | (1 Rating) |
| Upload Date: | 02/20/2009 |
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