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Subject: Radiology
Topic: Um..?
Lecturer: The usual

Shifting /Date: 2nd shifting, August 9 2008
Trans group: Chicken Naguits :D
Trauma classification
\u2022
Grade 1
o
subscapular hematoma non-expanding
o
contusions and small infarcts
o
no parenchymal laceration
\u2022
Grade II
o
less than 1 cm laceration
o
non-expanding perirenal hematoma
\u2022
Grade III
o
greater than 1 cm laceration
o
not extending to collecting system
\u2022
Grade IV
o
laceration with urinary extravasation
o
main renal artery or vein injury with
contained bleed
\u2022
Grade V
o
main renal artery thrombosis
o
shattered kidney
o
renal hilar injury with devascularization of
kidney
o
avulsion at UPJ

CT is highly useful for:
1. Diagnosing and staging renal injuries
2. Determining the depth of cortical

lacerations
3. The quantity of devascularized renal tissue
4. The status of the renal collecting system
5. The extent of peri-renal hemorrhage

Clas
s
Criteria
Contusions, small
corticomedullary
I

Lacerations that do not
communicate with the collecting
system

II
Laceration that communicates
with the collection system
III
Shattered kidney, injury to the
vascular pedicle
IV
UPJ avulsion, laceration of the
renal pelvis
Bladder
\u2022
Occurs in association with blunt pelvic trauma,
pelvic fractures or penetrating injuries
\u2022
Gross hematuria almost always accompanies
bladder rupture
\u2022
Up to 95% of patients with bladder rupture
present with gross hematuria
\u2022

The susceptibility of bladder to injury is
dependent on degree of distention, a distended
urinary bladder is much more prone to injury
than a nearly empty one

\u2022

Urine extravasation, whether intraperitoneal or
extraperitoneal, is dependent on the location of
the bladder. Intraperitoneal rupture often
results from a direct blow to a distended
bladder

\u2022
Delayed scans may help display extravasated
urine
Adrenal Adenoma
\u2022
Incidence in the population is 2-8%
\u2022
Diagnosis is often made as an incidental finding
on CT examination
\u2022
In patient with no known primary, an adrenal
mass is almost always a benign adenoma
\u2022

In a patient with a known neoplasm, especially
lung cancer, an adrenal mass is problematic
and diagnosing a metastasis versus and
adenoma is critical for prognosis

\u2022
CT findings
o
Size greater than 4 cm tend to be

metastases or adrenal carcinoma
- heterogeneous appearance and irregular
shape are malignant characteristics

o
Homogeneous and smooth are benign

characteristics
- intracellular lipid in adenoma results in low
attenuation on CT

o

Little intracytoplasmic fat in metastases
results in high attenuation on non-enhanced
CT

o

Non-enhanced CT (NECT)
- threshold 10 HU
- sensitivity 79%, specificity 96%

o

Contrast-enhanced CT (CECT)
-because majority of CT examinations in
oncology use IV contrast, the % washout is
useful after 10 minutes.
- adenomas have greater than 50%
washout after 10 minutes
-washout can also be used on adrenal
masses that measure >10 HU on NECT
- alternative is to do MR or PET

MARY YVETTE ALLAIN TINA RALPH SHERYL BART HEINRICH PIPOY KC JAM CECILLE DENESSE VINCE HOOPS CES XTIAN LAINEY RIZ KIX EZRA GOLDIE BUFF MONA AM MAAN ADI KC
PENG KARLA ALPHE AARON KYTH ANNE EISA KRING CANDY ISAY MARCO JOSHUA FARS RAIN JASSIE MIKA SHAR ERIKA MACKY VIKI JOAN PREI KATE BAM AMS HANNAH MEMAY PAU
RACHE ESTHER JOEL GLENN TONI

Subject: Radiology
Topic:
Page 2 of 8
MR findings:
\u2022

Chemical Shift
- most sensitive method for differentiating
adenomas from metastases
- sensitivity 81-100%, specificity 94-100%
- the difference in resonance rate of protons in
fat and water is exploited in chemical shift

-- intracellular lipid and water in same voxel
result in
summation of signal on \u201cin-phase\u201d and
canceling out of
signal on \u201cout of phase\u201d
\u2022
Spleen or muscle is used as an internal

standard to visually quantify signal drop-off
- liver is not a reliable standard because of
steatosis

Adrenocortical carcinoma
\u2022
Rare malignancy with a poor prognosis
\u2022
Reported incidence: 2 cases per million persons
\u2022
Tumors frequently are large, measuring 4-10
cm in cross-sectional diameter
\u2022
Arise from the adrenal cortex
\u2022
Bilateral in up to 10% of patients
\u2022
Approximately 50-80% are functional tumors,
with most causing Cushing syndrome
\u2022
Sign and symptoms
o
A large palpable mass, abdominal pain, or
Cushing syndrome
o

Cushing syndrome is the most common
clinical presentation in adults with adrenal
cortical carcinoma, although

o

Patients can present with virilization,
feminization, precocious puberty, or Conn
syndrome

o

In children, the most common clinical
presentation is virilization , followed by
Cushing syndrome

\u2022
Endocrine syndromes associated with
adrenocortical carcinoma
o
Cushing syndrome
o
Virilization and precocious puberty
o
Feminization
o
Primary hyperaldosteronism
MRI findings:
\u2022

A large mass
- lower signal intensity than the liver on T1-
weighted images and
- higher signal intensity than the liver on T2-
weighted images
- often, the tumor demonstrates
heterogeneously hyperintensity on T1- and T2-
weighted images, due to the central necrosis
and hemorrhage

\u2022

Coronal and sagittal images may be helpful in
determining adrenal origin of the mass, thus
differentiating it from renal cell carcinoma or
hepatocellular carcinoma, especially if CT is
equivocal

CT findings
\u2022
Large mass (>4 cm)
\u2022
Central necrosis or hemorrhage
\u2022
Heterogeneous enhancement
\u2022
Invasion into adjacent structures
\u2022
Venous extravasation into the renal vein or
inferior vena cave
Adrenal metastases
\u2022
Unilateral adrenal mass or enlargement
\u2022
Small masses (<1 cm)
o
Adenoma
o
Ganglioneuroma
o
Hyperplasia
o
Metastasis
o
Pheochromocytoma
\u2022
Large masses (>4 cm)
o
Carcinoma of adrenal cortex
o
Cyst or pseudocyst
o
Hematoma
o
Infection
o
Inflammation (eg, tuberculosis,
histoplasmosis)
o
Metastasis (eg, lung or breast related)
o
Myelolipoma
o
Neuroblastoma
o
Ganglioneuroblastoma or ganglioneuroma
o
Pheochromocytoma (eg, multiple endocrine
neoplasia)
Bilateral adrenal enlargement
Common causes: hemorrhage (eg in infants,

trauma, bleeding disorder), histoplasmosis, hyperplasia, metastasis (eg, lung or breast related), neuroblastoma, and tuberculosis

Uncommon causes: Addison disease, adenomas,

amyloidosis, carcinomas (eg, multiple, primary),
infection (ie, others), lymphoma,
pheochromocytoma (multiple endocrine neoplasia),
and Wolman disease (eg, familial xanthomatosis)

CT Findings
\u2022
Appear as focal masses or distortion of the
contour of the adrenal gland
\u2022
Smaller than 3 cm may be homogenous
\u2022
Large lesions may have central necrosis or
hemorrhage. These lesions are heterogenous
Subject: Radiology
Topic:
Page 3 of 8

and may have thick enhancing rims. They may
also invade contiguous organs such as the
kidneys.

\u2022
Attenuation values of less than 10 HU on
unenhanced
MRI Findings
\u2022
Are usually hypointense on T1-weighted images
and
\u2022
Relatively hyperintense on T2-weighted images
\u2022
The exception is metastatic melanoma, which
may be bright on T1-weighted images
\u2022

Occasionally, lesions may remain hyperintense
on long-echo time T2-weighted images,
mimicking pheochromocytomas

CASE: 43 year-old women with hypertension
\u2022

A middle aged woman presented to her primary
care physician with hypertension and episode
sweating. She was referred to a urologist who
obtained a 24 hour urinary vanillymandelic acid
(VMA) which was elevated

CASE: 35 year-old women with HPN
\u2022

A large, right-sided, inhomogenous, adrenal mass with a central area of low attenuation that represents hemorrhage or necrosis

Left: T1-weighted, a mixed isointense-to-
hypointense right adrenal mass
Right: T2-weighted, the right adrenal tumor has
high signal intensity
Pheochromocytomas
CT Findings
\u2022
Large tumors (often > 3 cm)
\u2022
They are usually round or oval masses with an
attenuation similar to that of the liver
\u2022
Larger lesions frequently demonstrate necrosis,
hemorrhage, and fluid-fluid levels
\u2022
As a result, they often appear inhomogenous
\u2022
Calcification is rare, but it is reported
MRIs
\u2022

Usually hypointense or isointense relative to
the liver on T1-weighted spin-echo (SE) images,
and

\u2022
They are highly intense on T2-weighted SE
images
\u2022

The reason for this difference is unknown, but
likely results from the high water content in
cellular homogenous tumors or the high water
content in necrotic regions

\u2022

Tumors that have bled show the features
typical of hemorrhage, depending on the age of
the hemorrhage

Normal Uterine Size:

By ultrasound, the normal postmenarchal
nulliparous uterus is 5-8 cm in length, 1.5-3 cm
thick, 2.5-5 cm wide.

Myometrium:

The normal myometrium is hypoechoic,
homogenous, and reasonably well demarcated
from the endometrial echos

Endometrial Structure:

The endometrium consists of a constant basal
layer (basalis), and a cycling functional layer
(functionalis). The functional layer includes a thin
compactum layer and a thick spongiosum layer.

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