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EIXOCORTICOTRÓFICO
Profa. Dra Rafaela Vieira CorrêaHomeostaseMedicina 2009.1
 
 
OBJETIVOS DEAPRENDIZAGEM
Compreender os mecanismosfisiológicos envolvidos naesteroidogênese adrenal
Diferenciar os mecanismosregulatórios envolvidos nofuncionamento do córtex e damedula adrenal
Conhecer as vias de interação entreo eixo hipotálamo-hipófise-adrenal.
 
 
Fig. 2.
 The urogenital ridge and adrenogonadal primordium. Urogenital ridge development resultsin formation of the kidneys, gonads and adrenal cortex. Specification of the metanephric kidneyand adrenogonadal primordium occurs first. Following contact with primordial germ cells, the fetaladrenal (composed of fetal zone and definitive zone) and bipotential gonad then separate. Thebipotential gonad differentiates into a testis or an ovary, depending on the genetic sex of theindividual. The adrenal gland continues to develop as the neural crest cells that will ultimatelybecome the adrenal medulla migrate to the center of the gland, and the process of cortical
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