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Dr. Niranjan Murthy H L
Asst Professor of PhysiologySSMC, Tumkur 
 
RESPIRATORY INSUFFICIENCY
Narcosis
,
other pharmacologic influences
,
hypoxia
, and
 pathologic processes
 
 reduce excitability of respiratory neurons
respiratory failure
 
Narcotic drugs & respiratory depression:
Leads to reduced Pa
O2
& increased Pa
CO2
.Carries best prognosis & amenable to Rx.Narcotic drugs also diminish metabolism.Complications of narcotic poisoning-(vi)Asphyxia(vii)Microbial infections(viii)Circulatory depression(ix)Renal functional derangements(x)Hypo or hyperthermia(xi)Consequences of therapeutic measures
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