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Examville.com - Physiology - Cardiac Output
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REGULATION OFREGULATION OFCARDIAC FUNCTIONCARDIAC FUNCTION
A. INTRINSIC REGULATIONA. INTRINSIC REGULATION
The amount of blood pumped by theThe amount of blood pumped by theheart each minute (heart each minute (
cardiac outputcardiac output
) is) isdetermined by the rate of blood flow intodetermined by the rate of blood flow intothe heart from the veins (the heart from the veins (
venousvenousreturnreturn
))
STARLING’S LAW OF THESTARLING’S LAW OF THEHEARTHEART
““The mechanical energy set free on passageThe mechanical energy set free on passagefrom the resting to the contracted state is afrom the resting to the contracted state is afunction of the length of the muscle fiber..”function of the length of the muscle fiber..”
Increasing the resting muscle fiber lengthIncreasing the resting muscle fiber length, as with, as withincreasing end-diastolic volume, will result in anincreasing end-diastolic volume, will result in anincreasedincreasedforce of contractionforce of contractionmanifested as an increased peakmanifested as an increased peakpressure and increased stroke volumepressure and increased stroke volume
The reverse will be true if fiber length or end-diastolicThe reverse will be true if fiber length or end-diastolicvolume is decreasedvolume is decreased
Also calledAlso called
Heterometric AutoregulationHeterometric Autoregulation
or intrinsicor intrinsicregulation due to changing length of cardiac muscle fiber regulation due to changing length of cardiac muscle fiber
of 00
Regulation of Cardiac Fxn_ECG
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