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DNA structure and DNADNA structure and DNAreplication
 
eplication
Outline DNA nucleotide structure in terms of sugar (deoxiribose), baseOutline DNA nucleotide structure in terms of sugar (deoxiribose), baseand phosphate.and phosphate.
State the names of the four bases in DNA.State the names of the four bases in DNA.
Outline how DNA nucleotides are linked together by covalent bondsOutline how DNA nucleotides are linked together by covalent bondsinto a single strandinto a single strand
Explain how a DNA double helix is formed using complementary baseExplain how a DNA double helix is formed using complementary basepairing and hydrogen bonds.pairing and hydrogen bonds.
Explain DNA replication in terms of unwinding the double helix andExplain DNA replication in terms of unwinding the double helix andseparation of the strands by helicase, followed by formation of the newseparation of the strands by helicase, followed by formation of the newcomplementary strands by DNA plymerase.complementary strands by DNA plymerase.
Explain the significance of complementary base pairing in theExplain the significance of complementary base pairing in theconservation of the base sequence of DNAconservation of the base sequence of DNA
State that DNA replication is semiconservative.State that DNA replication is semiconservative.
 
 
DNA nucleotideDNA nucleotide
 
 
Bases in DNABases in DNA
Chargaff’s rule is a rule about DNA. In 1949, Erwin Chargaff, a Czech-American scientist, noticed that inevery DNA molecule the amount of adenine (A) bases was always equal to the number of thymine (T)bases, and the amount of guanine (G) bases was equal to cytosine (C) bases. Two scientists calledJames Watson and Francis Crick used Chargaff’s rule to discover that the “rungs” of DNA’s double helixwas made of a base pair, and that the bases were joined by hydrogen bonds. This means that adeninewould hydrogen-bond with thymine, and guanine with cytosine.
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