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enzim HEPAR.ppt

enzim HEPAR.ppt

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Published by: Habiby Habibaty Qolbi on Mar 12, 2013
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10/07/2013

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ENZIM HEPAR 
 Wahyu SiswandariBagian Patologi Klinik PPD UNSOED
 
FUNGSI HEPAR 
1.Metabolisme karbohidrat, protein, lemak 2.Sintesis protein tubuh3.Penyimpanan Fe, glikogen, lemak, vitamin4.detoksifikasi5.Ekskresi hasil akhir metabolisme:bilirubin, amonia, urea
 
 Tes enzim hepar
 AST (SGOT) dan ALT (SGPT)
 Aspartate Transaminase/Serum Glutamic-Oxaloacetic Transaminase
 Alanine Aminotransferase/Serum Glutamic-Pyruvic Transaminase
Level ALT tertinggi dijumpai di hepar 
Level AST tertinggi di hepar, otot rangka,, jantung
 ALT dan AST meningkat cepat pada jaundice viral
Peningkatan ALT lebih tinggi daripada AST padanekrosis hepar akut
 AST dan ALT meningkat pada: infark miokard, infarkginjal dan lain-lain
 ALT : 10-40 U/l, 7-35 U/l, AST : 14-20 U/l, 10-36 U/l

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