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SKRIPSI NURHAYATI (090610011)

SKRIPSI NURHAYATI (090610011)

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Published by Nurhayati Akila JN
larvasida, daun belimbing wuluh (Averrhoa bililmbi L.), Aedes aegypti
larvasida, daun belimbing wuluh (Averrhoa bililmbi L.), Aedes aegypti

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Published by: Nurhayati Akila JN on Mar 13, 2013
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04/15/2013

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UJI EFEKTIVITAS LARVASIDA EKSTRAK DAUNBELIMBING WULUH (
 AVERRHOA BILIMB
L.)PADA
AEDES AEGYPTI 
SkripsiDiajukan ke Program Studi Pendidikan Dokter Universitas Malikussaleh sebagai pemenuhan syarat untukmemperoleh gelarSarjana Kedokteran
NURHAYATI090610011PROGRAM STUDI PENDIDIKAN DOKTER UNIVERSITAS MALIKUSSALEHLHOKSEUMAWE2013
 
Uji Efektivitas Larvasida EkstrakDaun Belimbing Wuluh(
 Averrhoa bilimbi 
L.
)
pada
Aedes aegypti 
Oleh: NurhayatiAbstrak Latar belakang
:Demam Berdarah Dengue (DBD) adalah penyakit yangdisebabkan oleh virus dengue dan nyamuk 
Aedes
aegyptisebagaivekto penularannya.Virus dengue sangat endemik di negara tropis.Salah satucara penanggulanganDBDdengan memutus mata rantai penularan.Daunbelimbingwuluhmemilikikandunganaktifyangdisebutsaponin, flavonoiddantanin.Kandunganzat aktif didugamemilikikemampuansebagai larvasida.Tujuandari penelitianiniadalahmengetahuiefektivitaslarvasida ekstrak daun belimbingwuluh (
 Averrhoa bilimbi
L.)pada
aedes aegypti
dinilaidariLC
50
danLC
99
,sertadarihubunganantarakonsentrasidenganjumlahkematianlarvapada waktu 24 jam.
Metode
:Besar sampel pada penelitian ini adalah360larva
Aedes aegypti
yangmencapaiumur4 hari,dibagimenjadi6kelompokujiyaitu0g/L(kontrol),2,5g/L, 3,75 g/L,5g/L,20g/L,dan 35g/L.Masing-masingkelompokberisi20larva
.
Setiap kelompok diulangsebanyak3kalidandiberimakanhati ayamrebusselamapenelitian
.
Datadiperoleh daripengamatankematianlarva
Aedes aegypti
 pada waktu 24 jam perlakuan.LC
50
danLC
99
ekstrakdaunbelimbing wuluhdiperolehdarianalisaprobitdanhubunganantarakonsentrasi dan kematiandiujidenganujikorelasispearman.
Hasil
:NilaiLC
50
7,287 g/L dan LC
99
22,343g/L.Hasilujinormalitaskolomogorv-smirnov,didapatakanhasilsebarandata tidak berdistribusi normal(p≤0,01).Ujikorelasispearmanmemilikihubungan yang bermakna(p≤0,01).
Kesimpulan
:Ekstrak daun belimbing wuluh (
 Averrhoa bilimbi
L.)memilikiefektivitaslarvasida pada
Aedes aegypti
karenamemilikinilaiLC
50
danLC
99
danterdapathubunganyangbermaknamenurutujistatistikantarapeningkatankonsentrasiekstrakdenganjumlahlarvayangmatipersatuanwaktu.
Kata kunci
: Larvasida, Daun belimbing wuluh (
 Averrhoa bilimbi
L.),
Aedesaegypti
 
 Larvacides Effectiveness Test of Averrhoa bilimbi Leaf (Averrhoa bilimbi 
L
 .) Extract 
on
Aedes aegypti 
By: Nurhayati
 Abstrac Background 
: Dengue Hemorrhagic Fever (DHF) is a disease caused by thedengue virus and the mosquito Aedes aegypti as a vector of transmission. Denguevirus is highly endemic in tropical countries. One way to control dengue fever bybreaking the chain of transmission. Averrhoa bilimbi leaf extract (Averrhoabilimbi
L
.) has some active components, saponins, flavonoids and tannins, sothat Averrhoa bilimbi leaf has larvacide ability. The purpose of this experiment is finding out the effectiveness larvacide Averrhoa bilimbi leaf extract on Aedesaegypti ability which is gained from LC 
50
and LC 
99
value, also from thecorelation between concentration and count of larva mortality at 24 hours test.
 Method 
: 360 samples of Aedes aegypti larvae ≥4 days are used for thisexperiment. Divided into 6 groups of experiment, which is 0 g/L (control), 2,5 g/L,3,75 g/L, 5 g/L, 20 g/L, 35 g/L. Each container was given 200 ml Averrhoabilimbi leaf extract solution, contained 20 larvaes and replicated three times. During the experimentation, larvae are fed with boiled chicken livers. The result of experiment is coming from observation of the mortalities of the larvae at 24hours test. Probit analized is used to count LC 
50
and LC 
99
. The correlationbetween concentration and count of larva mortality are tested with spearmancorelation test.
 Result 
: The LC 
50
value is 7,287 g/L and LC 
99
value is 22,343 g/L. Result fromkolmogorov-smirnov normality test, all data not showed normal distribution(p≤0,01). The result of spearman corelation test for all data had siginficancedifference (p≤0,01).
Conclution
: Averrhoa bilimbi leaf extrac
 Averrhoa bilimbi
L
.
 )
haseffectiveness larvacide on Aedes aegypti because Averrhoa bilimbi leaf extract has LC 
50
and LC 
99
value and there is significance correlation based on statistical test between concentration elevation and count of larva mortalityat 24 hours test.
 Keyword 
: larvacide, Averrhoa bilimbi leaf 
(
 Averrhoa bilimbi
L
.
)
,
Aedes aegypti

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