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Chapter III Pharmacokinetics
DURGE RAJ GHALANghalan_raj@hotmail.com
 
Learning Objectives
1.
Describe the physicochemical factors that influencethe
absorption
of drugs from enteral and parenteralroutes of administration, their 
distribution
withinthe body,
metabolism
(or 
biotransformation
) andtheir routes and mechanism of 
excretion (ADME)
.
MetabolismandExcretionare calledElimination
 
 
2.
Explain how dose, bioavailability, rate of absorption,apparent volume of distribution,total clearanceand elimination half-lifeaffect the plasma concentrations of a drug after administration of a single dose.3. Describe the factors that determine the time-courseof systemic accumulation of a drug administered byinfusion or multiple doses.
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usaama

A very good review of pharmacokinetics. Simple and clear

reply02 / 17 / 2010
01 / 04 / 2010This doucment made it onto the Rising List!
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