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VOLUME 18 NO. 3 n inside.dukemedicine.

org n March 2009

special section

Benefits
In this issue, 4 pages of news
about your Duke benefits

Pay for college


Although companies and other organiza-
tions are eliminating or reducing benefits
to tighten budgets during the recession,
Duke has expanded its employee tuition
assistance program for faculty and staff.
In January, the benefit expanded to cover

A new home for the PA Program


up to $5,250 in tuition reimbursement
and nine courses per calendar year.
Page 7
Facility highlights commitment to new models of care
ABOVE: Duke’s Physician Assistant Program is now located at 800 S. Duke St. near downtown Durham. Photo by kelly malcom
Stretch your dollars
Duke Credit Union seminars are free,

F or the first time since its creation in 1965,


the Duke Physician Assistant Program has
a home of its own — at the former Blue Cross
Open House
The Duke PA program will host an Open House from 4-6
and they save you money by helping
you get a handle on household budgeting,
understand finances or receive timely
information on big financial moves, such
and Blue Shield of North Carolina headquar- p.m. on March 12 at 800 S. Duke St. in Durham. Guided as housebuying.
tours and refreshments will be available.
ters near downtown Durham. Page 8
“We have four times the space we had in
our previous building and all of our spaces gradual expansion plans for the program and
are designed to meet the program’s needs,” a greater commitment to innovations in health
Stay up to date
said Patricia Dieter, MPA, PA-C, director of care. Duke is the birthplace of the physician The new Lynda.com program can help
the PA program. assistant concept and, with Duke’s commitment you stay up-to-date on emerging Web
and multimedia technologies through
Last year, the announcement of Duke’s to new models of care, it’s only fitting that the online tools and tutorials available
agreement with BCBSNC to lease the building program now has a home to match its heritage. anytime, anywhere.
came with Duke Medicine’s commitment to see DUKE PA, p.2 Page 9

inquiry now open events

Research under pressure Knightdale clinic opens What to do in March


Find out about the basic and Duke Medicine expands to The calendar moves to page
clinical research ongoing at Eastern Wake County with 15 this month.
Duke’s Center for Hyperbaric new facility.
Page 15
Medicine and Environmental
Page 3
Physiology.

Page 11
2 Inside Duke Medicine March 2009

F RO M t h e c o v e r

DUKE PA, cont. All 3 hospitals


“It is no secret that this country is now Magnet status
facing a growing shortage of primary Duke Raleigh Hospital has achieved Magnet
care physicians, and we don’t yet designation for excellence in nursing by the
know how much worse this shortage American Nurses Credentialing Center (ANCC).
will become,” said Justine Strand, Only 5 percent of the nation’s hospitals have
DrPH, PA-C, chief of the physician earned this designation, the highest level of
national recognition to health care organizations
assistant division. “PAs are going to be
that demonstrate sustained excellence in
a key component in the evolution of nursing care.
new models of care and will be needed
to ensure adequate access to care for “It is an honor to receive such prestigious
recognition for our hospital and a testament to
Americans in the future.”
the extraordinary nurses and entire hospital
“PAs are an efficient and flexible team who work together every day to provide
component of the solution to the the very best care to our patients,” said Doug
shortage,” Strand said. “We can Vinsel, chief executive officer of Duke Raleigh
graduate a PA in two years, whether Hospital. Duke University Health System is the
only hospital system in the Triangle with all
primary care or specialty.”
hospitals receiving Magnet designation. Go to
Brandon Wyche, first-year student, http://inside.dukemedicine.org to watch
said: “It’s good to know that you are video featuring chief nursing officers from each
preparing to do something that will of the hospitals.
Chinika Reynolds takes a standardized patient’s blood pressure during a clinical problem
ultimately fill an urgent need in the
evaluation. Photo by erin pratt “This is the highest honor a U.S. hospital can
community.” receive for its nursing program and further
Wyche, a former emergency said. “The profession has doubled in “more spacious and more conducive to supports the exceptional skill and dedication of
medical technician, was introduced to numbers in the last decade, and tripled teaching and learning.” Duke nursing” said Victor J. Dzau, M.D.,
the profession while working with PAs in the last 15 years.” The Duke Endowment helped sup- chancellor for health affairs and president and
in hospitals. There were about 74,000 PAs port the start-up cost of the expansion chief executive officer of the Duke University
Health System. “For all three of our hospitals to
“The diversity of options available practicing in the United States in 2008. of the PA Program. BCBSNC provided
receive this distinction truly signifies the
to physician assistants is what initially In North Carolina, there is about one the renovations, and worked closely world-class care available to all of our patients.”
attracted me to the PA program, and practicing PA for every six practicing with Duke to transform the historic
the options seem to be growing almost physicians. building into an energy-efficient and The Magnet Recognition Program recognizes
health care organizations that demonstrate
every day,” Wyche said. “You don’t “I’m confident that PAs will play user-friendly facility.
excellence in nursing practice and adherence to
have to choose just one area like an integral part in revolutionizing our The new facility has a master national standards for the organization and
emergency medicine, surgery or family health care system and I am excited classroom that can accommodate 90 delivery of nursing services. Applicants undergo
medicine.” about the prospects for the future,” said students. The master classroom in the a rigorous evaluation that includes extensive
Under the supervision of a physi- Chinika Reynolds, a first-year student. former on-campus location at Hanes interviews and review of nursing services. Duke
Raleigh Hospital was notified of Magnet
cian, PAs take patient histories, perform Importantly, PAs — like other House accommodated 66 students.
recognition on Feb. 13 after a three-year-long
physical examinations, order laboratory physician extenders on the modern The facility, at 800 S. Duke St., application process. Durham Regional Hospital
and diagnostic studies and develop health care team — increase patient also offers four physical diagnosis received Magnet designation in November after
patient treatment plans. In all states, access to health services by extending suites, where students conduct physical completing as similar lengthy process. The
including North Carolina, PAs have the the time and skills of the physician. diagnosis through clinical problem designation was given to Duke University
authority to write prescriptions. “Several patient satisfaction studies evaluations with standardized patients. Hospital in 2006.

Their job descriptions are as have shown that patients are as satisfied The visits are recorded and given to the “We are so appreciative of the more than 225
diverse as those of their supervising with care provided by PAs and nurse students for self-evaluation. employees who were directly involved in this
physicians, and may include patient practitioners as they are with physician Other features of the new location process,” said Mary Graff, director of nursing
education, medical education, health care,” Morgan said. include a diagnostic methods lab, study special projects and the Magnet program at
Duke Raleigh Hospital.
administration and research. At Duke, the program is growing. rooms and lounges for students, faculty
“PAs work in all of the specialties The traditional incoming PA class size and staff offices, conference rooms, and “Our nursing staff are so deserving of this
of medicine,” said Perri Morgan, was 45 students. The class beginning in two kitchens available to students. designation, and I am so proud to be the
Ph.D., PA-C, director of physician August will have 70. The layout of the new location nursing leader of this amazing group,” said
Rosemary Brown, chief nursing officer.
assistant research. The continued gradual expansion brings students, faculty and staff
Nationally, 37 percent of PAs of the program is dependent on avail- together. Research shows there are clear benefits to
work in primary care. Other specialties able clinical rotations within Duke “Before, we were spread out over hospitals that are awarded Magnet status and
where PAs are most common include University Health System and avail- multiple floors and now we are all in to the communities they serve in consumer
confidence, recruitment and retention and in
cardiovascular and orthopedic surgery, ability of PA scholarships through our own space together,” Reynolds said. maintaining quality of care. Magnet designation
dermatology and emergency medicine. the School of Medicine to recruit top Her fellow student, Wyche, said is maintained for four years. During that period,
“Recent growth of the PA students, Dieter said. the new facility “feels worthy of the the ANCC monitors facilities to ensure high
profession has been dramatic,” Morgan She described the new location as reputation of the Duke PA program.” n standards of care continue to remain.

■ ■ I N S I D E V olume 1 8 , I ssue 3
Inside Duke Medicine, the employee Contact us Staff
newspaper for the Duke University Health Campus mail: DUMC 104030 Editor: Anton Zuiker
System, is published monthly by Duke Deliveries: 2200 W. Main St., Managing Editor: Mark Schreiner
Medicine News & Communications. Suite 910-B, Durham, NC 27705 Science Editor: Kelly Malcom
Phone: 919.660.1318 Designer: Vanessa DeJongh
Your comments, story ideas and photo E-mail: editorinside@mc.duke.edu Inside Online Editors:
Bill Stagg and Erin Pratt
contributions are always welcome and Credits Intern: Sara Portoghese
appreciated. Deadline for submissions Cartoon: Josh Taylor Copyright © 2008
is the second Friday of each month. Duke University Health System
March 2009 Inside Duke Medicine 3

C
Q ALEN
& A D AR p r i vac y a l e r t

Beknighted – Duke Medicine


opens clinic in Eastern Wake County
In and around the Triangle, no area is growing
as fast as Wake County. The population of
Wake County grew by 32.6 percent— adding
204,744 people— between 2000 and 2007,
according to state government estimates.

Comparatively, Durham County grew by 14.1


percent and Orange County by 10.2 percent.

The March 2 opening of


Duke Medicine in
Knightdale, a state-of-the-
art facility with primary
care and urgent care
What to do about
services, is the latest lost, stolen data
example of how the Duke Duke Medicine in Knightdale
University Health System Laptop computers, thumbdrives,
doug vinsel, ceo opened for business Monday,
continues to make personal digital assistants, and other
investments in Wake
March 2, 2009 mobile devices make accessing
County. The Knightdale clinic now gives Eastern Location: 162 Legacy Oaks Drive, Hwy 64 electronic information easier and
Wake County the same world-class specialty and I-540, Knightdale, NC 27545 often more efficient.
services available to patients in Durham, Raleigh,
Morrisville and other communities. Primary Care: Family medicine for all ages. These portable devices may also
Mon-Fri 8 a.m. – 5 p.m. be easily lost or stolen. If patient
We asked Doug Vinsel, CEO of Duke Raleigh information or other sensitive
Hospital, to elaborate on Duke Medicine’s Wake Urgent Care: Open seven days a week, information (Social Security numbers,
County strategy and explain how the new Duke 8 a.m. – 8 p.m. personal financial information, etc.)
Medicine in Knightdale answers the growing is stored on these portable devices,
need for health care services there. Specialty Care: Gastrointestinal medicine, patient’s identity and Duke could
pulmonary medicine, cardiology and cardiology, gastroenterology and be at risk.
orthopedics. pulmonology. Then, over the next 12
Why open a clinic in Knightdale? to 18 months, other specialties will be To prevent the
Appointments: 919-232-5205 or
added. The mix of specialists was based loss of data:
The establishment of a Duke Medicine 1-888-ASK-DUKE (375-3853)
on the demographics of the area and
presence in Knightdale at the intersection • Do not store sensitive information
the gaps in specialty care that currently
of Interstate 540 and US 64-Business is on laptops or mobile devices.Use
with our two-track approach to exist and are projected to continue to
consistent with our strategy of trying remote
long-term success. exist over the short to intermediate
to create a presence along the I-540 access
term. Many of the specialists who will
corridor. In looking at opportunities How are Wake County residents services like
initially work at the Knightdale clinic the Duke
within Wake County, Knightdale stood responding? will also continue to have a presence on Medicine
out as a high-growth community with
The early response is encouraging; the Duke Raleigh Hospital campus in VPN service,
minimal existing medical services.
there were more than 25 appointments the Duke Medicine Plaza. virtual PIN
Locating our new building at the
scheduled during the first day that the and other
intersection of I-540 and 64 makes Will the quality of care match the
appointment line was open. Bottom Citrix
access for patients in the northern and high quality across Duke Medicine? services to
northeastern tier of Wake County very line: I think this is a location that will
Absolutely! Protocols and evidenced access the needed information.
convenient. And, the new building is be successful short and long term and
based care practices will be consistent Information saved on these servers
on 16 acres, which certainly creates the one that will allow for a synergistic is secure and backed up nightly.
relationship between Duke Raleigh at this site with those at other Duke
opportunity for future evolution of this Medicine locations. We’re proud to be
facility into a health campus. Hospital, which is just 7 miles away. • If you must store information on
bringing even more of Duke’s world- mobile devices, encryption of the
I would be remiss if I didn’t What’s special about the facility? class care closer to Wake County’s information is required. Contact
mention the communications from The facility itself is spacious, attractive residents. your technical support person for
the university and the health system and easily accessible. I think the thing assistance.
Did Duke Medicine recruit new
on March 2 that provided a clear that is most special about the location
physicians, nurses and staff to fill If your laptop or mobile
update on how Duke is being impacted is the fact that it’s a 40,000-square-
the facility? device is lost or stolen:
by the current financial crisis. Within foot building that, when fully ramped
the Health System, current efforts up, will accommodate 25 physicians All of the physicians who will occupy
• Contact your information security
to manage expenses and achieve a — 14 specialists and 11 primary care the Duke Medicine of Knightdale site officer or the DHTS Service Desk at
sustainable financial structure for doctors. The critical mass of primary will be Duke PDC Physicians (specialty 684-2243.Security support personnel
the future are critically important. and specialty care will be a beacon for care) or Duke Primary Care Physicians are listed at https://www.iso.duke.
But, as pointed out in the email to both existing residents and newcomers (primary and urgent care). Many of edu/iso/isop/isl.php. Contact Duke
Duke Medicine employees, expense to Wake County seeking a single site these physicians are new recruits, Police at 684-2444 and Risk
management is only one component where they can receive virtually all of although some will be redeployed from Management at 684-3277.
that will drive our long-term success. their physician care. within the Health System. Similarly,
• Provide the last known location of
The other driver will be strategic, many of the staff who will support
What specialty care physicians will the device.
well-designed, fiscally disciplined the practices are new Duke Medicine
investments in projects that can drive be located at Knightdale? employees, while others are existing • Identify all patient health informa-
growth — the Knightdale project is a By late spring, Duke Medicine in employees who have chosen to transfer tion or sensitive information stored
good example of this and is consistent Knightdale will include orthopedics, to this new location. n on the device.
4 Inside Duke Medicine March 2009

AT A G LAN C E B ULLETINS


■ ■ a c c oun t in g

Health care receipts


I’m impressed with how people here can take an idea … and turn it


due by April 15
into something big. People here are overachievers in the sense that they Faculty and staff who enrolled in 2008 health
can make big things happen starting with relatively modest resources. or dependent care reimbursement accounts
must submit receipts for services provided from
Jan. 1 through Dec. 31, 2008 to WageWorks
— Nancy Andrews, M.D., Ph.D., dean of the the School of Medicine, in her inaugural State of the School address by April 15, 2009, for reimbursement.

Claim forms and supporting documentation


must be post marked or faxed to WageWorks
by April 15. Claims for 2008 submitted after
■ ■ I N S I D E view ■ ■ i t fi g u r es this date will not be reimbursed.

Claim forms are available online at http://


hr.duke.edu/forms, or at the Human
Resources office, 705 Broad St. in Durham.

6,288
■ ■ min d + b o d y

Register: Spirituality and


health research workshops
The Duke University Center for Spirituality,
Theology and Health is offering two five-day
The number of hours worked in
research workshops on July 20-24 and Aug.
calendar 2008 by hospice volunteers 17-21 that compress a two-year post-doctoral
at Duke Home Care & Hospice. fellowship into five days.

They will be the only


places in the world
Source: Duke Home Care & Hospice
where specific training
on religion, spirituality
and health research can
be obtained from faculty
active in the field for
nearly 25 years.
■ ■ pi c t u r es
In each of the past four years, the workshops

Hospice center opens with ceremony, gifts


have been over-subscribed, so it is important
to register now. The courses are strongly
recommend for graduate students, researchers
early in their careers, and seasoned researchers

M oney raised by the Duke wishing to shift work into this area. There are
Hospital Auxiliary again is no degree requirements for participation.

benefiting Duke Medicine’s facilities, Tuition scholarships are available for students
patients and families. with extreme financial hardships and
A donation from the auxiliary exceptional academic potential. Because of the
will provide flat screen TVs for all intense nature of this training, which includes
individual mentorship with Harold G. Koenig,
12 patient rooms — plus TVs for the
M.D., and other workshop faculty, the
family room and the nurses area — at workshops are limited to 25 participants each.
Duke HomeCare & Hospice’s new
facility on North Roxboro Road For any questions, write koenig@geri.duke.
edu, or go to: http://www.spiritualityand-
in Durham. The facility, called the
health.duke.edu.
Hock Family Pavilion, had its ribbon-
cutting on Feb. 24. ■ ■ wo r k + f a mil y
“Providing the funding to buy
the TVs allowed hospice to use their Find a summer camp
funds for other areas of the facil- for the kids
ity,” said auxiliary director Renea Are you a Duke University Health System
Participating in the Feb. 24 ribbon-cutting at the new Hock Family Pavilion hospice inpatient
Hunnings. employee and already wondering what to do
facility were, left to right, Mary Ann Black, Duke University Health System assistant vice with the kids thus summer?
“We would not have been able president for community affairs, Deborah and Jim Hock, Gary Hock, DUHS CEO Victor J.
to provide that level of amenity Dzau, M.D., and state Sen. Vernon Malone. Not pictured are Starr Browning, executive It’s never too early too plan.
without a committed sponsor like the director of Duke Home Care and Hospice, Duke University President Richard H. Brodhead
Duke Hospital Auxiliary,” said Starr and Paul Newman, DUHS vice president for ambulatory care. Photo by nancy shambley Check out the list Duke University Staff &
Family Programs has compiled of summer
Browning, executive director of Duke money through three gift shops, a assistants, bereavement counselors camps and programs taking place in Durham,
HomeCare & Hospice. “They have been volunteer office and fund-raising events. and volunteers. Orange and Wake counties. The list includes
a strong partner in the work we do.” The new hospice facility In another gift, the auxiliary athletic and academic camps sponsored by
The auxiliary has helped sponsor a features 12 private patient rooms, donated $10,000 to provide heart pa- Duke as well as other arts and recreation
wide range of projects at Duke Hospital camps in the area.
24-hour skilled nursing care and tients with pillboxes uniquely designed
since 1950, with particular emphasis an interdisciplinary team of nurses, for easy opening by anyone who has Find all the details here: http://hr.duke.edu/
on patient and family needs. It raises social workers, chaplains, nursing arthritis or gripping problems. n family/camps.php
March 2009 Inside Duke Medicine 5

■ ■ P e r son a l fin a n c e Q: How do you jumpstart performance? ■ ■ poli c ies

How to obtain
a duplicate W-2 A: A Quiz Bowl! Human Resources
policies updated
The 2008 W-2 forms needed to file tax Duke Human Resources has updated the
returns were distributed in late January. Duke Staff Handbook, which gives an
overview of policies and procedures. The
In an effort to better serve faculty and staff, handbook, which is distributed to newly
Duke University has standardized the hired staff during orientation, includes
process for requesting duplicate tax forms. several updates that have been incorporated
into the HR Policy Manual. More information
An employee must complete a Tax
about these changes, as well as an electronic
Document Request Form to request a
copy of the handbook, can be found at
replacement of a lost or misplaced W-2
http://hr.duke.edu/policies.
form. This form is available on the Corporate
Payroll Services Web site: http://www.
payroll.duke.edu/forms/forms.php.
■ ■ r e c o g ni t ion
This change is necessary to obtain an
original employee signature authorizing the Stroke Association
request. The fees associated with this honors Goldstein
request are stated on the Tax Document
Larry Goldstein, M.D., professor of medicine
Request Form and remain unchanged from
By Melissa Schwarting tion screen as questions, photographs (neurology) at Duke and the Durham VA
prior years.

I
Medical Center and director of the Duke
t’s 6:45 a.m. on a frigid Wednesday and diagrams begin to appear asking
For more information about W-2 forms, Stroke Center, was honored February by the
morning. Twelve wide-eyed questions like, “Name a neuropeptide American Stroke Association with the
talk with your department payroll represen-
tative, visit the Corporate Payroll Services neurosurgery residents sit around a neurotransporter.” William Feinberg
Web site, or call 684-2642. conference room table as Michael The room fills with clicking sounds Award for Excellence
Haglund, M.D., Ph.D., program as the residents begin pounding small, in Clinical Stroke.
director of the neurosurgery training remote controlled buzzers in their The award honors
■ ■ h ono r s program, steps up to a podium at the hands signaling their desire to answer “significant achieve-
front of the room. the question. ment in the clinical
Fulkerson among 6 But this isn’t a typical lecture. The questions keep coming, along investigation and
‘Sammie’ award winners Haglund transforms into a referee as with the enthusiastic responses of the management of
goldstein stroke.”
William J. Fulkerson, M.D., senior vice teams are formed and the room is sud- residents, as team after team comes to
president of clinical affairs for the health denly filled with a competitive energy the front of the room for their turn in Goldstein is a senior fellow in Duke’s Center
system, is among six people recently selected that could rival a Super Bowl match up. the hot seats. The format is single round for Clinical Health Policy Research, and
for the 2009 This event is called Quiz Bowl, principal investigator of Duke’s American
elimination comprised of five rounds.
“Sammie” awards, Stroke Association–Bugher Foundation
an idea conceived by Haglund, who Three correct answers in round one
named for distin- Center for Stroke Prevention Research.
guished political
used an experience with his children meant one team was moving on to face
scientist, educator as inspiration. “This concept was their next opponent and one team was Read more about the honor and Goldstein’s
something I’d seen when my kids work at http://inside.dukemedicine.org.
and human rights out of the competition.
Search “Goldstein.”
activist Samuel participated in a junior Bible quiz,” The initial concept started two
DuBois Cook. he explains. “It makes learning fun … years ago when Cory Adamson, M.D.,
FULKERSON The winners were [the residents] get into it.” Ph.D., assistant professor of surgery ■ ■ c on t inuin g e d u c a t ion
announced at the Quiz Bowl is not just fun and and neurobiology, started administering
12th annual dinner and awards ceremony games. What started as an experiment
Save 40 percent on
weekly quizzes to the residents. Those
held at the Washington Duke Inn & Golf Fuqua business courses
to make the learning process more with the top scores at the end of the
Club. All were chosen in appreciation of
interesting, has turned into a successful year were eligible to be named “resident All Duke faculty and staff are eligible for a
their work in furthering Cook’s legacy.
teaching model. scholar” and win a cash prize. 40 percent tuition reduction on all non-
Fulkerson, head of the Duke Hospital “[The residents] seem to pay degree executive education programs at the
When Haglund took over as
Diversity Leadership group, was cited for Fuqua School of Business.
more attention and enjoy the friendly program director last spring, he wanted
providing leadership in the area of diversity
competition,” Haglund explains. to build upon Adamson’s creative Fuqua is a premier provider of business
and inclusion, helping enhance diversity
“We’ve also seen the scores come approach. He soon introduced Quiz education for working professionals. A range
education, and encouraging all members to
up a lot since we started doing this,” of programs are available, designed
consider the connection between diversity Bowl, which takes place every three
specifically for professionals in all stages of
and patient care. Haglund says. He estimates that quiz months and includes questions from the career development.
scores improved from an average of 24 weekly quizzes administered during the
Also recognized were Peter Klopfer, Ph.D.,
percent in 2007 to around 83 percent prior 12 weeks. Eight executive education programs are
emeritus professor of biology at Duke and
since the Quiz Bowls began in 2008. available throughout the year. Two new
civil rights advocate; Martha Shumate On this morning, the champion-
programs available in fall 2009 are:
Absher, associate dean for education and Haglund is careful to note that part ship round has Renee Reynolds, M.D., Fundamentals of Management (for first-time
outreach at Pratt School of Engineering; of the improvement can be attributed and Hamid Aliabadi, M.D., squaring managers, and experienced managers without
the Rev. Mel Williams, senior pastor at the
to other recently launched efforts in off against Betsy Hughes, M.D., and formal training) and High Potential Executive
Watts Street Baptist Church and founder of
Walltown Neighborhood Ministries Inc. and
the department to encourage resident the incumbent winner, Ciaran Powers, (for mid-level managers and executives).
Duke seniors Dinh Phan and Flint Wang. participation and make them feel more M.D., Ph.D. Following an intense Programs are held at the R. David Thomas
engaged in the design and implementa- round of questioning, Powers and Executive Conference Center on Duke’s
Named for the first African-American
tion of the residency training program. Hughes are the victors. campus and also at the Washington Duke
faculty member at Duke, the Cook Society
was founded in 1997 to recognize and
As the game kicks off, teams of No rings or trophies are awarded Inn & Golf Club.
celebrate the African American presence at two are formed. Chief residents are to the winners. Instead the winners and To learn more, visit http://www.ee.fuqua.
Duke. For more information and to find a paired with more junior residents and a guest are taken to dinner, at a restau- duke.edu, contact a client relations
list of past award recipients, go to http:// mid-level residents join together. rant of their choosing, by Haglund and coordinator at (919) 660-8011 or e-mail
www.duke.edu/web/cooksociety. All eyes are fixed on a large projec- execed-info@fuqua.duke.edu.
another member of the faculty. n
6 Inside Duke Medicine March 2009

Arou nd th e hospitals

Durham rehabilitation institute:


A team approach to recovery
D urham Rehabilitation Institute
(DRI), located on the seventh floor
of Durham Regional Hospital, provides
a comprehensive, multidisciplinary
approach to recovery. The rehabilita-
tion team is dedicated to helping each
patient regain independence and reach a
higher standard of living.
DRI staff treat patients with a
variety of traumas and disorders,
including strokes, spinal cord injuries,
amputations, joint replacements and
neuromuscular disorders. The DRI team
and rehabilitation nursing staff will tell
you that it’s the team approach that
makes this possible.
“In the gym, we have a multidisci-
plinary team that creates a personalized
rehabilitation plan for each patient
and makes sure that he or she is able
to take advantage of all the technology
and resources available,” explains
Raphael Orenstein, M.D., medical
director of DRI.
A Multi-Disciplinary Approach
Kristen Tell and Kim Dao, physical therapists at the Durham Rehabilitation Institute, work with a patient at the parallel bars.
Teamwork is essential for positive Photo by tom wooters
outcomes at DRI. The care team is
comprised of physicians, physical The Latest Technology ferent and exciting. “Our main
therapists, occupational therapists, Several of the latest advances goal is to help patients learn
therapy aides, speech therapists, reg- in rehabilitative technology are how to do things for themselves.
istered dieticians, nurse practitioners, available at DRI, including the This is different than many of
care managers, referral coordinators, Biodex De-Weighing System — the other units. It requires a lot
rehabilitation nurses, certified nurse a fully adjustable harness system of teaching and a different type
assistants, a licensed assistant therapist that allows patients to practice of care. We consider at every
and a recreational therapist. walking but removes as much of turn how much we are supposed
The teamwork starts every morning their weight as necessary. This to help our patients versus how
with a group meeting at 8:30 to review system gives patients opportuni- much they are supposed to do
each new patient being admitted. The ties for exercise and also speeds for themselves.”
charge nurse, nurse manager, nurse recovery and enhances ability. On 7-3, each patient receives
practitioner, physician, therapists, care Other tools are practice full nursing care with the same
managers and referral coordinators dis- rooms and an automobile Angela Webb, an occupational therapist at the Durham medical acuity as on other
cuss each patient and become proactive Rehabilitation Institute, helps a patient. Photo by tom wooters units, but in addition they must
simulator. There is also a practice
about the resources needed for them. A kitchen and a practice living complete at least three hours of
primary nurse is assigned to each new room so patients can experiment gym. Unit 7-3 is the inpatient unit for therapy at the gym a day. “There
patient. This is unique to rehab. with tasks such as food preparation and DRI, and the bed capacity was recently is a lot of coordination that happens
The DRI care team also meets wheelchair maneuvers. expanded from 22 to 30 beds. between nursing and therapy — it’s kind
weekly to discuss each patient’s short The technology, combined with the The Unit 7-3 care team includes of like a dance,” says Perry.
and long term goals, and their progress comprehensive, team-oriented approach registered nurses, certified nursing Ask any team member what his
to date. to rehabilitation, has led to DRI’s being assistants, dietitians and health unit or her favorite part of working at DRI
“We talk about how we are going recognized by the Uniform Data System coordinators. In addition, the Food & is, and he or she will tell you “it’s my
to get the patient where they need to be, as being in the top 10 percent nationally Nutrition and Environmental staff are patients.” Physical therapist Kristin Tell,
which is functioning independently and in patient outcomes. often commended for their customer- relays an experience that is common
ready to go home, and then together focused service in letters from 7-3 at DRI, “A patient’s grandma told me
we do what’s needed to get there,” says Care Outside the Gym patients. ‘thank you for giving me my grandson
Sherri Pearce, BSN, MSN, director of An additional team of professionals Regina Perry, RN, describes how back.’ Moments like this are what I love
Adult Health. provides care outside the Rehabilitation nursing for Rehabilitation is both dif- about this profession.” n
Benefits A Quarterly Supplement to Inside Duke Medicine

hr.duke.edu n inside.dukemedicine.org n March 2009

va l u i n g t e a m w o r k

Coach K: Remember you’re part


of the team.

Page 8

financial planning

Stan Jones, a utility worker with Duke’s Housekeeping Operations, is using Duke’s employee assistance program to work
toward an associate’s degree in electrical technology from Durham Tech.

Paying for College Duke University Federal Credit


Employee tuition program expands skills, advances professional development Union seminars can help
you stretch dollars during

S itting in a classroom at Durham


Technical Community College, Stan
Jones studied a blackboard filled with
“When I’m done, I’ll have an associate’s
degree and be a registered nurse
the recession.

Page 8
algebra, fractions and word problems. without having a lot of loans to pay off.”
Jones, a utility worker with
Duke’s Housekeeping Operations, Daniel Rudd, clinical staff assistant at The Preston Robert Tisch
H e a lt h y l i v i n g
Brain Tumor Center. Rudd is taking evening classes at Alamance
paused for a moment, recalled the Community College.
math formulas he reviewed over the
week, then picked up a pencil and electrician at Duke. “When I heard work location is in another state.
started scribbling in a notebook. about the program, I jumped on the The tuition assistance is available
“Good job,” Durham Tech math opportunity,” said Jones, 48. “I’ve to full-time staff and faculty with at
instructor Richard Noble told Jones, as wanted to learn more about wiring and least two years of continuous service
he looked over Jones’ work. circuit boards for a while.” at Duke. Since 2007, Duke has reim-
Jones is participating in Duke’s Although companies and other bursed employees nearly $1.5 million
employee tuition assistance program organizations are eliminating or reduc- for tuition.
to work toward an associate’s degree ing benefits to tighten budgets during Lois Ann Green, director of
in electrical technology from Durham the recession, Duke has expanded its Duke Benefits, said the program
Tech. He’s among 1,000 staff and employee tuition assistance program for supports Duke’s long-term staffing and
faculty members who have enrolled in faculty and staff. In January, the benefit professional development strategies by
the tuition benefit in recent years for expanded to cover up to $5,250 in expanding the internal pool of talent to
career-related courses and degrees at tuition reimbursement and nine courses fill positions at Duke.
accredited North Carolina schools. per calendar year. Employees can also “It helps us to build a more
As part of his job at Duke, Jones request a waiver to take courses at skilled workforce and boosts retention The Mobile Farmers Market
cleans floors in East Campus buildings accredited schools in other states if because employees can grow and have makes healthier living easier.
and hopes the new skills he learns in the courses are not offered in North the opportunity to advance within
school will open doors to become an Page 9
Carolina, or if the employee’s primary see TUITION, p.10
8 Benefits March 2009

Stretching your dollars during a recession


D iane Gifford does her best to
manage money wisely. She creates
savings toward those goals.
Developing a priority list for paying
a monthly budget, uses online banking down credit cards with high interest Duke Credit Union
to pay bills on time and regularly sets rates is also key.
aside money in a savings account. But People of all income levels
Seminars
it’s the unexpected – vehicle repairs, are “feeling the crunch,” Dowdy said. Ten Steps to Financial Success
brokenh appliances or medical bills – “It’s not what you make; it’s how you March 17, 12:30 p.m. at the Duke
that drain her savings. use what you earn,” she said. A “nest Credit Union, 2200 W. Main St.
“I put the money into the savings egg” for unexpected expenses and
account with the best intentions of emergencies guards against dipping Homebuying
keeping it there, but you know how into savings, she added. March 24, 12:30 p.m. at the
things go,” said Gifford, a clinical trial “If you put money into your Searle Center
coordinator with Duke Clinical Research savings and then take it out to pay
Institute. income with these suggested budget guideline bills or unexpected expenses, then that Go Online:
Gifford attended a recent Duke University allocations: 35 percent for housing (mortgage, is not a savings account,” Dowdy said. “If you To register for a seminar, visit
Federal Credit Union workshop on “Building a rent, utilities, insurance); 25 percent for other know you’re going to need new tires or a new http://www.dukefcu.org and select
Better Budget,” an important topic during the expenses (food, clothing, entertainment); 15 car in the next year, start saving for it now.” “seminar sign-up” under Quick Links;
economic recession, which, financial advisors percent for transportation (car payment, fuel, Gifford, the Duke Clinical Research Institute send e-mail to scottie.dowdy@duke.
suggest, is a good time to revisit a personal maintenance); 15 percent to pay debt (credit trial coordinator, has a new goal after attending edu or call (919) 660-9745.
monthly budget. cards, student loans); and 10 percent for savings. the seminar: leave the savings undisturbed by
“If you’re paying attention to the news and “When creating your budget, you should only creating an accurate budget with an allocation
volatile market, it’s a scary time for everyone list sources of income that you actually receive for unexpected expenses. Video
right now,” said Scottie Dowdy, a financial on a regular basis, not overtime or bonuses,” “I’m determined to get on track and have
Dowdy said. See a video about budgeting at
counselor with Duke Credit Union. “The key is to money set aside for unexpected expenses,”
In addition to budgeting, Dowdy suggested http://www.hr.duke.edu/finance
manage your money as best as possible.” she said. “That’s my financial goal for 2009.” n
Managing money starts with preparing an creating a chart with goals for longer-term needs By Missy Baxter, Senior Writer,
accurate and balanced budget based on net such as a house or new car, and to earmark Office of Communication Services

The letters on the front of the jersey


B efore an audience of several
hundred faculty and staff, Mike
Krzyzewski boiled down his coaching
Coach K’s style at Duke is not
much different. “Beyond the basketball
court, we talk to our guys a lot about
philosophy to one mantra: character, about being humble and using
Whether playing for Duke, or for the platform they have to help others,”
the USA Basketball team, “You play he said. In answer to questions from the
for the [team] letters on the front of Primetime audience about developing
the jersey,” he said, brushing his hand teams, he stressed the importance of
proudly across his chest, “not the name being honest with each other, and
on the back. developing communication skills and
“You don’t just get 12 people trust “so that the first time you talk
together and call it a team,” he said, [tough] isn’t the first time you talk.”
“just like a school is not a school just Krzyzewski, who has coached more
because you have people occupying than 950 basketball games at Duke,
jobs. How do you get people to work reminded the audience that the Duke
together?” name garners respect in the world, even
The answer, he told employees outside of basketball, and that the Duke
during the Primetime forum in January, name elevates all of us.
is taking time to develop the culture of “We are lucky to be part of
Duke men’s basketball coach Mike Krzyzewski speaks with women’s basketball coach Joanne
teamwork. McCallie. Coach K talked about teamwork during the Primetime employee forum in January. something bigger than us,” he said.
Krzyzewski recalled his first “But always remember that Duke is
meeting with the USA national team, Later, Krzyzewski cultivated the a car bomber. “I wanted the guys to great because of its people. Anything
long before he coached them in the standard of service by introducing the understand what selfless service was any one of us does is important. An idea
Olympic gold-medal game last national team to veterans such about,” Krzyzewski said. “Not only you have has the chance of being the
year. “[The meeting] was not as Scotty Smiley, an MBA had these guys served, they wanted to idea that makes Duke better. That’s why
about offense or defense,” student at the Fuqua School serve again. After the veterans spoke, we should always act as a team to make
he said. “It was about the of Business. Smiley was the team – Wade, LeBron and all – were good things happen.” n
standards we were going blinded in Iraq while trying crying. I thought, ‘we have a chance. By Marsha Green
to live by.” to protect his squadron from These guys have a heart.’ ” Writer, Office of Communication Services
March 2009 Benefits 9

Grab and go at the gardens opportunities

Learn latest technology


Mobile farmers market makes healthy eating easier through Lynda.com
A new online training resource offered through
Duke’s Office of Information Technology (OIT) is

J oyce Newton’s office is a


stone’s throw from the summer
enabling faculty, staff and students to learn the
latest technological tools with video tutorials
Duke Farmers Market. But as a available anytime, anywhere. For Richard Lucic,
staff specialist with the Pediatric associate chair of the Computer Science
Neonatology Department, she Department, the pilot program through Lynda.com
offers a convenient way for him and his students
doesn’t always have time for
to stay up-to-date on emerging Web and
market shopping. multimedia technologies.
That’s why she’s a fan of the
Duke Mobile Farmers Market. She “These technologies change rapidly – just keeping
up as new versions come along can be a real time
signs up for both the summer and
sink,” said Lucic, who includes the videos as part
winter mobile market to get fresh, of a class he teaches in the Information Science
local vegetables nearly all year and Information Studies (ISIS) program.
round.
Lucic is among more than 200 Duke faculty,
“It is so convenient,” she said.
staff and students who have participated in
“I just drive to Duke Gardens after OIT’s Lynda.com pilot since it was launched in
work on Tuesdays, and a box of veg- October. Lynda.com offers more than 30,000
gies is waiting. I really miss the few online training courses on topics ranging from
weeks between growing seasons.” Microsoft Word and Excel to Web design and
With the mobile market, faculty computer programming.
Fresh food is to be had at the Duke Mobile Farmers Market.
and staff pre-pay for produce and OIT is providing a limited number of individual
pick up their share of the harvest accounts for Duke users during the yearlong
once a week. This year, seven local pilot. Staff and faculty can review the training
“The farmers introduce us to vegetables we might tutorials online (from Duke or at home) or can
farmers/vendors will provide fruit,
vegetables and flowers, with deliver- otherwise never see — like purple cauliflower. use designated workstations at the ACT
Warehouse lab, Multimedia Project Studios, the
ies starting April 7 at Duke Gardens That was different!” Center for Instructional Technology and the Link
(with one farmer delivering in Perkins Library. Tutorials in PHP, Dreamweaver,
Joyce Newton, staff specialist with the Pediatric Neonatology Department
to Durham Regional Microsoft Excel and PowerPoint have been among
Hospital). The produce, the most popular with Duke staff, who comprise
about 75 percent of program participants to date,
price, size of share and following enhancements this year:
said Christine Vucinich, OIT’s training coordinator.
number of delivery weeks Meals to go at • Most farmers offer payment plans
vary among farmers. mobile market to reduce the up-front cash layout. As more jobs throughout the university and health
“My husband and I • Britt Farms will begin pickup at 3 system demand technology skills, online training
Rosie’s Plate offers fresh entrees, can help users at all levels, Vucinich said.
are local potters, so we p.m. to make it more convenient
side dishes, salads, soups, snacks
recognize the importance for employees who work an early “Online training provides an opportunity to get
and desserts for take-out.
of supporting community shift. Other farmers will offer quick questions answered and for staff at any
businesses,” Newton Each week, employees can order pickup from 4 p.m. to 6 p.m. location to get the training they need when they
food from Rosie’s Plate up to one need it, not weeks or months later,” she said.
said. “And the farmers • Rosie’s Plate, a restaurant special-
day in advance of Duke’s Mobile
introduce us to vegetables izing in gluten-free, shellfish-free The training helped Terry Banfich get up to speed
Market. View the menu and order
we might otherwise online at RosiesPlate.com or call
and peanut-free food, will offer during a recent Microsoft Word upgrade in Duke
never see — like purple fresh, local, organic meals-to-go. Law School’s Alumni & Development Office. It also
(919) 833-0505.
proved useful as she transitioned into a new job as
cauliflower from Vollmer Farmers accept customers on
a trainer in Central Development’s IT department.
farms. That was different!” a first-come basis until they reach
More than 300 employees LIFE, Duke’s employee wellness capacity. n “Everything and anything is there, and it’s there at
participated in the 2008 mobile program. Based on employee any time, even if you’ve just got five minutes to
By Marsha A. Green
spend,” Banfich said. “It’s a great tool for giving
market, organized by LIVE FOR feedback, LIVE FOR LIFE made the Writer, Office of Communication Services
folks the essential training and tips that can help
make our work lives more effective and efficient.”

OIT will gather user feedback this spring to


evaluate whether the program will be imple-
mented on an ongoing basis next fall.
Learn more and enroll in the mobile farmers market at
http://www.hr.duke.edu/mobilemarket or contact By Cara Bonnett
Go Online: More information about OIT’s on-
Jason Horay at (919) 681-0504 or Jason.Horay@duke.edu
line technology training program is at http://
www.oit.duke.edu/help/training/online/
10 Benefits March 2009

TUITION, cont.
Duke as they expand their skills,”
Tuition Assistance Tips for Tuition
she said. by the numbers Reimbursement
Results show the program is 2008 Participation • Read program details at http://www.
meeting Duke’s goals of getting a hr.duke.edu/tuition
diverse group of employees to utilize $1,036,673 Tuition paid by Duke
• Discuss professional development with
higher education opportunities and 549 Staff and faculty enrolled your supervisor to determine courses
encouraging managers to help staff related to your current job or
develop career goals. 88 Participants at Durham Tech continued career growth at Duke.
In a recent survey of staff and 75 Percent of female participants • Download the Employee Tuition
faculty who participated in Duke’s Assistance Program application at
$53,060 Average salary of participants
employee tuition assistance program, http://www. hr.duke.edu/forms
87 percent said knowledge gained by 38 Average age of participants and complete it with your supervisor.
using the benefit will help them better • Complete and return the application
9.45 Average years of service
perform in their jobs; in a similar by mail or fax before the first day of
survey of Duke managers, 85 percent “When I’m done, I want to each class to request reimbursement.
agreed that the benefit helped improve
employee performance. be a wealth of knowledge Video • If approved, Duke Benefits will send an
e-mail with your eligibility confirmation
The benefit program evolved for Duke to use.” See a video about the tuition benefit and reimbursement request form.
from the 2003 recommendations of with “Ask The Expert” at http://www.
Patricia Agbai, health unit coordinator, hr.duke.edu/tuition • Within 60 days of completing each
the Women’s Initiative, which called
Heart and Lung Transplant Unit class, submit to Duke Benefits a copy
for greater opportunities for profes- of the e-mail confirmation, proof of a
sional development. It was designed to “C” or better in coursework and a
provide more employees with oppor- to 8 a.m. and attends evening classes reimbursement request form com-
tunity for professional development by several times a week at Durham Tech. Green said. pleted by the school attended.
offering reimbursement for classes not Going back to school is challenging, “And with the way Duke is
offered at Duke or access to courses he said, but the rewards of career growing globally, this will also help the
at local community and state colleges development are priceless. When he increasing number of Duke staff and Fast Facts:
with lower tuition. graduates in about two years, he will faculty based outside the state.” The cost of books is not covered. And
Before the program was intro- be the first person in his immediate Convenience is a big factor if you voluntarily terminate employment
duced, only courses at Duke were family to receive a college degree. for Daniel Rudd, a clinical staff within two years of receiving more than
assistant at The Preston Robert Tisch $2,500 in tuition reimbursement, you
covered. Today, the program offers “It’s a lot of hard work to be back
must repay 50 percent of the amount
employees more options, including in school with a full-time job and Brain Tumor Center at Duke. He’s
over $2,500.
evening classes at community colleges. family, but I’m learning a lot of skills,” taking evening classes at Alamance
Durham Tech, University of North said Jones, who joined Duke in 2004. Community College, near his home in
Carolina at Chapel Hill and North Patricia Agbai, a health unit coor- Prospect Hill in Caswell County.
Carolina Central University are now dinator in Duke University Hospital’s “When I’m done, I’ll have an
among the most utilized schools. Heart and Lung Transplant Unit, is associate’s degree and be a registered
As a result of the expanded also tapping into the tuition benefit to nurse without having a lot of loans to
program, participation and diversity learn new skills that will expand her pay off,” Rudd said.
of enrollment have increased – from responsibilities at Duke. In addition to using the Employee
320 staff and faculty with an average She’s pursuing a bachelor’s degree Tuition Assistance Program, Rudd
salary of $66,172 in 2006, to 549 in social work at Shaw University, her is hoping to eventually enroll in
employees with an average salary of first degree. She’s on track to graduate Duke’s new Registered Nurse Tuition
$53,060 in 2008. Minority enrollment later this year. Assistance Program to continue
increased from 19 percent in 2006 to “In working with patients in the developing his skills.
40 percent in 2008. Transplant Unit, the social work skills “It’s great that Duke assists

Benefits
“Since we expanded the program I’m learning will allow me to help employees who want to advance their
to include other schools, there’s been a families who are coping with major careers,” Rudd said. “I love helping
lot more participation among non- medical challenges even more,” Agbai the patients at Duke. By using the
exempt employees, skilled labor staff said. “When I’m done, I want to be a tuition assistance program to get my
Benefits is published quarterly by
and minorities, which is wonderful wealth of knowledge for Duke to use.” degree, I will be able to do even more Duke’s Office of Communication
because we want all Duke employees Although most Duke employees to help others.” Services as a supplement to Inside
to have the opportunity to develop use the tuition benefit at local colleges, This semester, Jones, the utility Duke Medicine. Benefits invites
employee in housekeeping, is taking your feedback and suggestions
professionally,” Green said. there is growing demand for the tuition
for future story topics. Please call
Adding community colleges makes program in satellite offices. To address two courses in English and math at
(919) 681-4533 or send e-mail to
it easier for healthcare workers and this, Duke expanded the program this Durham Tech. working@duke.edu
non-exempt employees with non- year to allow employees to apply for a “Nowadays, almost every machine
or appliance has electronic components Editor: Leanora Minai
traditional schedules to tap into the waiver to attend accredited out-of-state (919) 681-4533
tuition benefit, Green said. schools in specific circumstances. and circuit boards,” he said. “When leanora.minai@duke.edu
Take Jones, the utility worker with “That’s especially helpful for I get my degree, I’ll be able to
Assistant Vice President:
Duke’s Housekeeping Operations. employees in highly-specialized fields work on those.” n Paul S. Grantham
He’s a father of four who works the who might not be able to find the By Missy Baxter, Senior Writer, Office of (919) 681-4534
paul.grantham@duke.edu
third-shift at Duke from 11:30 p.m. courses they need in North Carolina,” Communication Services
The Science & Research Supplement to Inside Duke Medicine

VOLUME 18 NO. 3 n inside.dukemedicine.org n March 2009

news F EATURE

HIV-1 budding from cultured lymphocyte.


Multiple round bumps on cell surface
represent sites of assembly and budding of
virions. photo courtesy wikipedia commons

Antibody for The Duke Center for Hyperbaric Medicine and Environmental Physiology research runs the gamut from the effects of various pressures

HIV discovered on the human body to the influence of oxygen and carbon dioxide on cellular organelles. photoS courtesy HYPERBARIC MEDICINE

More than just ‘the bends’


By Michelle Gailiun

Duke researchers have for the first time


isolated an important antibody in human
serum that could potentially play a key role in By Kelly Malcom levels, pressure, and patient conditionlargest civilian facility in the world.

C
the design of an AIDS vaccine. lad in swim trunks and neoprene in each chamber. Hyperbaric oxygen is “Duke’s facility is not just
The research appears as a highlighted feature slippers, Jason, a medical student, administered for a variety of medical another hyperbaric chamber,” said
online in the Journal of Virology. climbed out of the chamber, drip- conditions, including most famously, John Freiberger, M.D., MPH, assistant
ping wet. Careful not to disturb the decompression illness, colloquially professor of anesthesiology. It is a
“The 2F5-like antibody is one of the gold
standards for what an HIV vaccine needs to
catheters put into his arms to measure known as “the bends.” unique facility where investigators can
induce, but no one had ever found it before his blood pressure and pulmonary Scuba divers and people who work readily research the effects of extreme
circulating in the blood of infected patients,” arterial pressures, he walked into an in pressurized environments who return environmental conditions on human
says Georgia Tomaras, PhD, associate adjacent room to recuperate from his to normal atmospheric pressure and physiology. Current projects deal with
professor of surgery, immunology and underwater exercise. aviators and astronauts who rapidly topics ranging from molecular biology
molecular genetics and microbiology in the
Jason had answered the call for fit transition to low pressure environmentsto the ill patient’s bedside and all strive
Duke Human Vaccine Institute and the senior
author of the study. volunteers to assist in a clinical study can develop bubbles of nitrogen gas for an in-depth understanding of the
to understand immersion pulmonary in their tissues. Symptoms can include biology of oxygen and other metabolic
The 2F5 antibody is especially valuable edema, a condition that causes some gases and their clinical applications.
skin rashes, joint pain, and more serious
because previous research has shown it can
divers’ lungs to suddenly fill with fluid. symptoms such as blurred vision and Freiberger is currently investigating
successfully neutralize 80 percent of transmit-
ted HIV viruses. “The condition is life-threatening the use of hyperbaric oxygen
and has caused some swimmers and “Our studies run the gamut from for the treatment of jaw
Now that researchers have found the antibody divers to die,” said principle investigator analyzing the effects of pressurized necrosis in patients who have
in circulating blood, Tomaras says they might
Richard Moon, M.D., professor of an- received certain drugs for
be able to find ways to duplicate or enhance it, suits on NASA astronauts to using
thereby boosting the body’s defense system. esthesiology and medical director of the chemotherapy that inhibit
Duke Center for Hyperbaric Medicine oxygen to help cancer patients.“ bone cell growth.
2F5-like antibodies belong to a class of and Environmental Physiology. “We’re John Freiberger, M.D., MPH In addition, he has a pilot
immune cells called broadly neutralizing assistant professor of anesthesiology
still unclear as to what causes pulmo- study to diagnose chronic
antibodies, one of the body’s most powerful
responses to infection. Only a small fraction of nary edema but it could be related to disorientation. Sever decompression carbon monoxide (CO) exposure and
patients with HIV make these antibodies and high pressures in the pulmonary artery sickness can be life threatening. examine possible prevention efforts in
they typically appear many months after initial or deficiencies in the way some people Treatment requires the admin- medically underserved populations.
transmission of the virus — at a point when clear their lungs of fluid.” istration of 100 percent oxygen in Hyperbaric oxygen is often
scientists feel it is too late to do much good.
This Navy-funded study is just a pressurized hyperbaric chamber, prescribed for victims of house fires
Tomaras, working closely with lead author one example of the ongoing basic usually for one or more periods of or suicide attempts who are acutely
Xiaoying Shen, led a team of researchers who and translational research projects 4-6 hours. Duke University Medical exposed to elevated CO, because
examined the antibodies present in 300 at the Center. Center is also where the Divers Alert in addition to its known immediate
patients infected with HIV-1. They found only
The facility, located in Duke Network (DAN), a network that toxic effects, CO can have devastating
one patient who had developed 2F5-like
antibodies, supporting the notion that they
South, contains an impressive series of provides educational and emergency long-term neurological consequences
are, indeed, very rare. chambers, the largest of which can hold information for recreational divers if not treated immediately. This has
up to 12 patients plus staff, as well as internationally, got its start. Duke important public health implications
Researchers discovered that the 2F5-like
water tanks for physiological studies. physicians routinely consult for DAN because even low levels of chronic
antibody was potent enough to block multiple
strains of HIV in the laboratory, but research-
In an area resembling the control and Duke’s hyperbaric facility is open CO intoxication may lead to subtle
room of a submarine, physicians and for emergencies 24 hours a day, seven but significant changes in neurological
see HIV, p.12 technicians constantly monitor oxygen days a week. Duke’s chamber is the see HYPERBARIC, p.12
12 Inquiry March 2009

HYPERBARIC, cont. Although CO is a known colleagues have found that exposure 1st Annual Human
toxin, it is also a normal product of to low levels of CO can promote the Research Protections
function if exposure persists over time. metabolism and may have important biogenesis of mitochondria, a process Program Workshop
Epidemiologic research has shown roles in cell signaling. Researchers at that may be intimately involved with Improving Research Quality
Duke’s hyperbaric center are the underlying mechanisms of wound
Duke’s hyperbaric facility is open utilizing the facility to examine healing and aging.
All those involved in clinical research at
Duke including investigators, coordinators,
for emergencies 24 hours a day, the effects of carbon monoxide “Duke’s hyperbaric facility is spe- and administrators are encouraged to
seven days a week. and oxygen on mitochondria, cial because of its commitment to both attend this workshop.
the powerhouse of the cell. quality clinical care and to high-caliber
Featured guest speakers will include:
that certain populations, especially “CO at high levels inflicts damage research,” said Freiberger. “Our stud-
recent Hispanic immigrants, may be through oxidative stress,” says Hagir ies run the gamut from analyzing the Greg Koski, PhD, MD, CPI, professor of
more likely than other ethnic groups to B. Suliman, Ph.D., assistant professor effects of low atmospheric pressure on anesthesiology at the Harvard School of
be exposed to chronic, low-level CO Medicine, speaking on Investigators’ Role
of anesthesiology. At low doses, NASA astronauts to using hyperbaric
in a Model HRPP.
exposure through the use of generators though, CO has an important role in oxygen to help cancer patients heal
or cooking grills indoors. This study cell signaling. Certain chemotherapy chronic wounds. We have the clinical Gregg Fromell, MD, executive director of
seeks to document CO exposure and drugs, such as doxorubicin, can and scientific depth to figure out how the Office of Human Research at the
develop strategies for prevention in all University of Pennsylvania, speaking on
cause mitochondrial damage and to make people better in a rational and
How to Engage Your Investigator in the
populations vulnerable to this disease. cardiac cell death. Suliman and her reproducible way.” n HRPP Process.

Gigi McMillan, BA, of the Children’s

A new direction for immune response


Brain Tumor Foundation, speaking on
Investigators’ Interactions with Vulnerable
Populations: Specific Considerations.

A n immune system response that


is critical to the first stages of
fighting off viruses and harmful
When: April 29 12:00 pm-4:30 pm OR
April 30 7:30 am-12:00pm

bacteria comes from an entirely Where: Searle Center


different direction than most scientists For more information and to register:
had thought, according to a finding http://crso.som.duke.edu/
by researchers at the Duke University
Medical Center.
“This finding will have important
implications in vaccine science and HIV, continued
autoimmune disease therapy develop- ers say they are not entirely clear if it played
ment,” said Michael Gunn, M.D., any part in controlling the virus in the
an immunologist and cardiologist at patient who carried it.
Duke and senior author of the study
The scientists were also struck by another
published in Nature Immunology. discovery: The 2F5-like antibodies arose
Type 1 helper (TH1) T cell Duke researchers have found that the immune response against infection begins concurrently with particular autoantibodies
immune responses are critical for differently than previously thought. file photo that may be a clue as to why these
the control of viruses and certain antibodies developed in this person and not
in others.
bacteria. Immunologists have gener- chemokine, that stimulates the They found that mice without the
ally believed that TH1 responses are migration of activated dendritic Ccr2 chemokine receptor that controls “Tomaras and her team have created the
induced by rare immune cells, called cells from peripheral tissues to lymph the migration of inflammatory mono- opportunity for us to isolate and study the
dendritic cells. When activated by immune cells that enabled the production
nodes. The researchers generated cytes had much lower accumulation of
of this very rare antibody,” says Barton
infection or vaccination, the dendritic a TH1 response in laboratory mice monocyte-derived dendritic cells and Haynes, MD, director of the Duke Human
cells were thought to move from that lacked this chemokine with TH1 responses. Vaccine Institute. “Our goal will be to
peripheral tissues into lymph nodes influenza viruses. The scientists concluded that understand how to trigger these cells to
to stimulate T cell responses. “We really thought the mice there is a blood-derived lymph node routinely make these kinds of antibodies
The Duke researchers found, would not be able to generate much dendritic cell type that has a key role before infection occurs.”
however, that the dendritic cells that of an immune response at all,” Gunn in developing acute T-cell responses. The research was funded by the National
stimulate TH1 responses didn’t come said, because they wouldn’t be able “For so long, dendritic cells from Institutes of Health and the Duke Center for
from peripheral tissues, but rather to mobilize dendritic cells. “The tissues were the obvious answer,” AIDS Research.
arose from monocytes, a common cell mice, however, had increased TH1 Gunn said. “We found out that that’s
type in the blood, that moved directly responses. We knew we had to find not always the case.”
into lymph nodes after infection. what was really causing the response.” The team now plans to look at
“The result speaks to the most One scientist who knew about the blood-derived dendritic cells under
basic principles of immune response these findings told Gunn the group different conditions to see if they may
to pathogens,” Gunn said. “It may would “never figure this out” because have other activities. “We observed Science Editor: Kelly Malcom
also explain the poor results we have their findings were so unconventional. the activity of these cells after TH1-
Inquiry features science and research-
seen in attempts to develop effective To solve the mystery, the Duke inducing stimuli, like influenza,” related news items from Duke Medicine
dendritic-cell vaccines.” team studied several different types Gunn said. “Next we’d like to study News and Communications and other
Gunn previously had identified of mice, which were missing other other types of immune stimuli to see Duke departments. To submit content,
a particular protein, known as a chemokines or chemokine receptors. how the cells respond.” n contact us at editorinside@mc.duke.edu
13 Inquiry March 2009

Drug combo may be effective against deadly melanoma


B y targeting and disabling a protein
frequently found in melanoma
tumors, doctors may be able to make
tumors completely disappear.”
The researchers discussed their
findings in an oral presentation on
“Not only was the treatment
well tolerated but a
one of the most deadly cancers and one
which is typically very unresponsive to
therapy,” said Georgia Beasley, M.D.,
the cancer more vulnerable to chemo- March 6 at the Society of Surgical surprising number of this a surgical resident at Duke and lead
therapy, according to early results of Oncology annual meeting, and results author on this study. “The next step
small group of patients
a clinical study conducted by research- of the study have been accepted for will be to continue testing the efficacy
ers in the Duke Comprehensive publication in the journal Cancer. had their tumors completely of this treatment in more patients, here
Cancer Center. The study was funded by Adherex disappear.” and at other centers.”
“In this pilot study, we gave Technologies, the company developing A larger phase II trial involving
Douglas Tyler, M.D., surgeon and senior
patients with advanced extremity the compound that was tested in 46 patients with advanced extremity
investigator on the study
melanoma a compound that had been combination with chemotherapy, the melanoma, using the same combination
shown in pre-clinical studies to weaken United States Department of Veterans of drugs, was designed to try and better
melanoma tumors by targeting a Affairs, the Duke Institute for Genome given under surgical conditions, through define the response rate in this popula-
protein expressed on the surface of the Sciences & Policy, and the Duke the artery and vein in the affected limbs. tion, Tyler said. This trial has recently
cancer cells. When chemotherapy was Comprehensive Cancer Center Melanoma often affects people on completed recruiting patients and data
then given by infusion, it was much Data from 16 patients treated their extremities, with a common sce- will be forthcoming, he said.
more effective compared to chemo- at Duke and the University of Texas nario being a mole that appears on the The incidence of malignant mela-
therapy given alone,” said Douglas MD Anderson Cancer Center were foot and then spreads up the leg. Up to noma is increasing at a rate faster than
Tyler, M.D., a surgeon at Duke and examined for this study. Half of them ten percent of patients with extremity any other cancer, with 60,000 new
the Durham Veterans Affairs Medical experienced a complete response — or melanoma develop multiple recurrences cases expected to be diagnosed this
Center, and senior investigator on this an obliteration of cancer — as a result in the extremity that cannot be treated year in the United States. Melanoma
study. “Not only was the treatment of treatment, Tyler said. The compound with surgery alone. that has spread beyond the primary
well tolerated but a surprising number — called ADH-1 — was delivered “These early results are very excit- site is rarely curable, and treatment
of this small group of patients had their intravenously and the chemotherapy ing because metastatic melanoma is options are limited. n

Genetic link between anger and health problems


M en with a common genetic vari-
ant produce more than twice as
much of a hormone known to increase
that made them angry. One of those
variants was associated with an average
increase in cortisol that was more than
blood pressure and blood sugar when twice as large (70 pg/ml vs. 30 pg/ml)
they are angry, according to researchers when compared with men possessing
from Duke University Medical Center. the other variant of the same gene.
The findings, presented March 6 at “Interestingly, one of the genetic
the American Psychosomatic Society’s variants associated with a prominent
annual scientific meeting, shed more affect on cortisol production is also
light on the notion that stress can known to alter the amount of receptor
trigger physiological changes that result protein the gene makes,” says Williams.
in the development of cardiovascular “This tells us that this variant is a
disease and type 2 diabetes. strong candidate to be responsible for
“We know that emotional stress the findings we observed.”
can lead to negative health outcomes “This work may provide a clearer
but our goal with this study was to understanding of the genetic and envi-
obtain a better understanding of the ronmental factors that combine to put
biological mechanisms behind this some men at greater risk for developing
phenomenon,” says Redford Williams, increased belly fat, type 2 diabetes and
M.D., director of Duke’s Behavioral cardiovascular disease,” adds Boyle.
Medicine Research Center and study The next phase of research will
co-author. Stephen Boyle, Ph.D., study co-author. men. One sample was collected during study large samples of people to
Researchers analyzed variants of “Serotonin is processed in the brain a five-minute resting period and the determine if men with the genetic
serotonin receptor genes, which regu- and controls the release of cortisol by other during five-minutes when they variant associated with larger cortisol
late effects of the neurotransmitter the adrenal grand. Cortisol is known described a recent event in their lives responses to anger seen in this study are
serotonin on emotions and physical to stimulate the production of glucose that made them angry. more likely to develop type 2 diabetes
functions, including levels of the stress and makes the influence of adrenaline Men with common variants of or cardiovascular disease.
hormone cortisol. more pronounced.” one of the serotonin receptor genes The research was supported by a
“We looked at specific points Researchers measured cortisol (5HTR2C) had increased cortisol grant from the National Heart, Lung
along a cascade of events,” says in two blood samples taken from 41 production when recalling a situation and Blood Institute. n
14 Inquiry March 2009

ESSAY

Lawmakers need a crash course in science


By Susanne B. Haga, IGSP all new Conservative members of

T he more than 50 rookie


congressional members who
headed to Washington in January
Parliament after the next elections,
specifically to address politicians’
lack of scientific expertise.
face a steep learning curve on Shadow Science Minister Adam
complex and, probably, unfamiliar Afriyie, the architect behind these
subjects, from foreign policy to new courses, says, “By building a
the budget appropriations process. base of scientific knowledge among
Many of these topics will involve politicians and officials, we aim to
science in one form or another strengthen the role of science in
— from scientific evidence under- policy making.”
pinning a specific policy to decisions Although the official orienta-
influencing the direction, investment tion for our new congressmen has
and advancements in our country’s already taken place, it isn’t too late
scientific enterprise. to impart some knowledge about
Consider that more than $38 subjects they almost certainly will
billion was spent by the federal be voting on. A good starting point
government in 2007 for health- would be with the scientific groups
related research and more than that already visit Capitol Hill to
$2 billion for energy research and present workshops and seminars.
technologies. That’s not as high The need for education works
as the numbers attached to the in both directions: the scientist-
stimulus package but large enough politicians, for instance, should be
to get our attention when it comes brushing up on Economics 101.
to educated decision-making. With a better base of scientific knowledge, members of Congress and Although public policy is
President Barack Obama has other politicians will be better equipped to make informed decisions on rarely based on scientific evidence
stated that he aims to promote science-related policy. ILLUSTRATION BY VANESSA DEJONGH alone, it no doubt could benefit
scientific research and incorporate from improved dialogue between
scientific evidence into policy de- hold a medical or doctorate degree fundamental understanding of experts and policymakers. Even
bates. This re-emergence of science with formal training in science and how research is conducted and seemingly unrelated policies on
as a national policy priority requires the scientific process. the strengths and weaknesses immigration and defense will have
a level of informed engagement that With the exception of a small implications for
hasn’t been seen in Washington in group of doctors and scientists, “The re-emergence of science as a national the scientific re-
some time. most members of Congress lack policy priority requires a level of informed search enterprise.
From medicine and health care the background to understand the Let us be
to food safety, energy, space and process of science and the subtle engagement that hasn’t been seen in sure that our
the environment, science will play a nuances that justify investments in Washington in a long time.“ policymakers are
key role in many of the policies our science and engineering or changes making informed
legislators will propose and debate. in existing priorities. inherent in any scientific dataset. decisions, for these decisions may
Members of Congress possess a What to do? We should take The Conservative Party in Great well impact generations to come.
range of backgrounds, including a lesson from the British and Britain recently announced that Susanne B. Haga is a senior policy analyst
ministers, sheriffs, farmers and encourage all freshman members it will include classes on scientific and an assistant research professor in the
accountants. More than 40 percent of Congress to take a crash course methodology and basic concepts Institute for Genomics Science & Policy at
hold law degrees, but only 8 percent in science to equip them with a in the orientation activities for Duke University. n

LE C TURE EVENT ONLINE

Chancellor’s Lecture Research Career Day Duke Articles


Clay Christensen, Harvard The first research Career Day A list of the most recent articles
professor and author of The will be held on Wed, May 6. To by Duke authors added to the
Innovator’s Dilemma, speaks on register, visit https://research PubMed (MEDLINE) database is
“The Innovator’s Prescription: careerday.wufoo.com/forms/ updated every Sunday and can
The Future of Academic Medicine duke-medicine-research-career- be found at http://www.mcli-
and Health Care.” March 11 at day-registration/. Registration brary.duke.edu/pubsupport/
10:30 a.m. Geneen Auditorium at will be open until April 15. dukeauthors
Duke’s Fuqua School of Business.
March 2009 Inside Duke Medicine 15

C ALEN D AR

March Your insider's guide to what's


happening at Duke Medicine

April 1 8:30 a.m. - 4:30 p.m.


Duke HomeCare and Hospice presents a grief
conference with nationally renowned speaker and
grief counselor Alan Wolfelt for both professionals
and lay people. Sarah B. Duke Gardens Pavilion.
There is a $100 fee to register. Six nursing contact
hours or 0.6 CEUs will be awarded. Register:
http://dhch.duhs.duke.edu/wysiwyg/down-
loads/Brochure_wilderness_of_grief.pdf

give
March 14 10 a.m.
“Scope Us Out” 5K Run/Walk Join Duke
Gastroenterology to raise money and support
the fight against colon cancer. Registration is
$15 and forms are due by March 6. Registration
includes t-shirt, goodie bag, and box lunch. Duke
Forest Al Buehler Cross Country Trail in Durham.
Register: http://www.dukehealth.org/
events/20090128164313538
March 28 10 a.m.
2009 Second Annual Triangle Kidney Walk
Duke Medicine is helping fight chronic kidney
disease as a premier sponsor of the Triangle Kidney
Walk. The 5K non-competitive walk will raise money
and awareness about kidney disease. Research
Triangle Park Headquarters. Details: 388-1602 or
http://www.trianglekidneywalk.org
Attend a seminar on “Race, Genetics and Health,” on March 18. This is the sixth in a monthly series that discusses the role of “racial”
March 29 9 a.m. - 12 p.m.
differences in explaining health disparities. Details below. illustration by vanessa dejongh
Build Blue and True 5K Come run a 5K in support
of Habitat for Humanity and your favorite rival Duke

do
Celebrate “Escultura Social: A New Generation of Art nursing school faculty and students, Duke Investiga-
or UNC. Cost is $20. All proceeds will go toward
from Mexico City” with live entertainment, hands-on tors, and DUHS nurses interested or engaged in
Habitat for Humanity of Durham and Chapel Hill. Lo-
projects and gallery hunts. Limited tickets available research. Clipp Research Building, Room 1017
cation: UNC Ranson-Hamrick Cross Country course
at the door only. Details: 684-3314
March 9 5:30-6:30 p.m. March 18 5:30-7:30 p.m. in Chapel Hill. Details: 668-5700
LIVE FOR LIFE’s Run/Walk Club starts its 12- March 24 5:30- 6:30 p.m. Race, Genetics and Health Seminar Series The
week session with a new breathing techniques ses- Duke Run/Walk Club Workshop – Prepping for sixth seminar in the monthly series under the theme
sion at 5 p.m. each Wednesday and strength training Races Whether you are planning on participating of Race, Genetics and Health will be presented by
class at 5 p.m. each Monday and Wednesday. Staff in a 5K run/walk race, competing in a triathlon or Fatimah Jackson and will focus on her method of
and faculty in the club meet 5:30-6:30 p.m. every running a marathon, preparation is a must. Meg group classification. These seminars are a forum for
Monday and Wednesday. Beginners meet at the East Pomerantz, director of the Duke Faculty Club, will the systematic examination of the role of “racial” How to submit:
Campus track, across from Whole Foods on Broad discuss the trials and tribulations from her own differences in explaining health disparities. Dinner
Send calendar listings to
Street. Advanced runners and walkers gather in front experience of training as well as teaching the group provided. RSVP, by March 11: donna.sullivan-
editorinside@mc.duke.edu
of Wallace Wade Stadium on West Campus. Details: what works best for your race of choice. Wallace khouri@duke.edu
hr.duke.edu/runwalk Wade Stadium, Alumni Box
March 18 6:30- 8:00 p.m. Want more info?
March 12 4-6 p.m. Duke Integrative Medicine Free Information
Visit us online at http://inside.
Session We invite you to a free information session

learn
Duke University Physician Assistant Program dukemedicine.org
Open House in celebration of the new facility on to explore Duke Integrative Medicine. In our state-of-
the-art healing environment, our expert physicians The Calendar is a monthly selection
800 S. Duke St. in Durham. Guided tours and light
March 18 12 p.m. and therapeutic staff will share information about our of events that feature the best of
refreshments. RSVP: Mildred.Woody@duke.edu
DUSON Research Conference Series with Shar- unique approach to healthcare--and how it can make happenings at Duke and Duke Medicine.
or 681-3159
ron Docherty, Ph.D. and Debra Brandon, Ph.D. A se- an enduring difference in your life. Light refreshments
March 22 12-4 p.m. ries designed to stimulate discussions and showcase will be served. Center for Living, Integrative Medicine
Free Family Day at the Nasher Museum of Art emerging issues in nursing and research. Open to Building, Room AB. Details: 681-2958
16 Inside Duke Medicine March 2009

on the web

Just a few of your colleagues who’ve


received High Fives:
Steven Adair, Duke Raleigh Security, A patient tells why Shelley McNair,
make sure patients, visitors and staff clinical nurse IV at Duke University
are safe: Hospital, is a true asset to Duke:

“Long after most employees have gone “Shelly hustles nonstop to help me get
home and into the evening while others through these difficult days. She takes
are working, this officer is checking the time to bathe me and does so with
doors (377 of them each night), much care and compassion — like I am
reminding employees to lock up and go her mother. She is a true asset to Duke!”
home and giving assistance to custom-
ers who find their way to Duke Raleigh
in the wee hours of the morning. For
five years, he has been making sure that
the campus is safe and secure so that Monette Mabolo, of Duke Raleigh
those sharing the shift can do their Nursing, was praised for bring her

5
work free from worry.” unit closer together:

ve a
“Monette Mabolo pays attention to

Gi
what we say and to what matters
most to us. She continues to come in
early to interact with the night shift

h
Arista Stewart, mammography

ig
technologist at Duke University and provide them with leadership and

H
Hospital, helped a patient feel at ease: support as well. To foster camaraderie
between the nurses and nursing
“Arista was so kind and sensitive. She assistants, she has them give report to
made me feel at ease. I have been each other at the beginning of the shift
going to her for the past three years. or whenever there are abnormal vital
She is wonderful and awesome.” signs that the nursing assistants note.
way
s id e O n line’s daily uke As a result, our unit has become more
In D
igh Fives is g the good work of
closely knit as a team.”

H of reco
Medicine
g n iz in
.
employees on of the well-dese
rved
t a selecti st few A patient thanked the entire CCU
Here’s jus olleagues over the la staff at Durham Regional Hospital,
en to c
praise giv h Five especially Mark Branch, M.D.:
months. e s a t le a st one Hig ine. Jolly John, clinical nurse II on 5300
line giv kemedic at DUH, made a lasting impression
Inside On h tt p :/ /inside.du
Our “family … would like to personally
. Che c k THANK YOU for the excellent, profes- on a patient’s mother:
every day igh
fo r m o re. w h o d e s erves a H sional care you gave our father from Sept.
“Jolly has been a blessing to my daughter
or g n
w a perso side
. Go to In t the
24th - Oct. 7th. The Lord truly blessed us,
If you kno e n t fo r m and myself while in the hospital. She was
ct” link a
and our father, during this time with ‘our
ur comm
Five, use o lick on the “Conta
very attentive and showed so much care
angels of care’ he provided. Your heartfelt
dc ge. and concern. My daughter remembered
Online an e O n li n e home pa concerns for our father (your patient) …
her name out of all nurses that took care
Insid
top of the could be seen and felt by the family. Our
of her. We love you, Jolly!”
hearts and prayers go out to the CCU
family. Thank you! Thank you! Thank
you! May God bless you as you care for
other families the way you cared for ours
and in your everyday life!”

Feedback Online any time Next issue


Tell us what you think at http://inside. You can download a pdf of this issue, The next print edition will appear
dukemedicine.org. Click on “About” suitable for emailing or printing, at April 1. The deadline for submissions
and fill out the feedback form. http://inside.dukemedicine.org for that issue is March 13.

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