Spastic paraparesis related alzheimer's disease Two types of AD exist: familial AD (FAD), which is found in families where AD follows a certain inheritance pattern; and sporadic(seemingly random) AD, where no obvious inheritance pattern is seen. Because of differences in age at onset, AD is furtherdescribed as either early-onset (younger than 65 years old) or late-onset (65 years and older). Early-onset AD is rare and generallyaffects people aged 30 to 60. Early-onset AD progresses faster than the more common, late-onset forms of AD.
After recovery from hypoxia (brought on by such conditions as carbon monoxide poisoning or acute respiratory failure), thepatient may experience total amnesia for the event, along with sensory disturbances, such as numbness and tingling.
Depending on the trauma’s severity, amnesia may last for minutes, hours, or longer. Usually, the patient experiences brief retrograde and longer anterograde amnesia as well as persistent amnesia about the traumatic event. Severe head trauma cancause permanent amnesia or difficulty retaining recent memories. Related findings may include altered respirations and LOC;headache; dizziness; confusion; visual disturbances, such as blurred or double vision; and motor and sensory disturbances, such ashemiparesis and paresthesia, on the side of the body opposite the injury.
Herpes simplex encephalitis
Recovery from herpes simplex encephalitis commonly leaves the patient with severe and possibly permanent amnesia.Associated findings include signs and symptoms of meningeal irritation, such as headache, fever, and altered LOC, along withseizures and various motor and sensory disturbances (such as paresis, numbness, and tingling).
Hysterical amnesia, a complete and long-lasting memory loss, begins and ends abruptly and is typically accompanied byconfusion.
In temporal lobe seizures, amnesia occurs suddenly and lasts for several seconds to minutes. The patient may recall an aura ornothing at all. An irritable focus on the left side of the brain primarily causes amnesia for verbal memories, whereas an irritablefocus on the right side of the brain causes graphic and nonverbal amnesia. Associated signs and symptoms may include decreasedLOC during the seizure, confusion, abnormal mouth movements, and visual, olfactory, and auditory hallucinations.
Retrograde and anterograde amnesia can become permanent without treatment in this syndrome. Accompanying signs andsymptoms include apathy, an inability to concentrate or to put events into sequence, and confabulation to fill memory gaps. Thesyndrome may also cause diplopia, decreased LOC, head-ache, ataxia, and symptoms of peripheral neuropathy, such as numbnessand tingling.