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Principles of Drug Distribution

Principles of Drug Distribution

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Published by Sunil
PRINCIPLE S OF DRUG DISTRIBUTION
PRINCIPLE S OF DRUG DISTRIBUTION

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Categories:Types, School Work
Published by: Sunil on Apr 06, 2013
Copyright:Attribution Non-commercial

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04/06/2013

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DRUGDISTRIBUTION
 
 
DISTRIBUTION
Definition:
“Process
where by an absorbed chemical movesaway from the site of absorption to other areasof the
body”
.
Following absorption
(skin, lung, or gastrointestinal tract)
or systemicadministration (IV, IP, IM) into the bloodstream,a drug distributes into interstitial andintracellular fluids.
 
 
Interstitial fluid
represents about
15%
of thetotal body weight.
Intracellular fluid
 
(fluid inside cells) -
40% 
of the total body weight.
Blood plasma -8%
 of the body weight.

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