Pharmacy UAS 2012

1) Pharmacy on medical/ dentistry focus on except: A) Drug development research B) Posology ( drug dose knowledge) C) Pharmacodynamic D) Drug prescription E) Pharmaceutics 2) Pharmaceutics, as one of the discipline in drug development, its main aspect was : A) Drug dosage technology B) Toxicology C) Pharmacodynamic D) Pharmacokinetic E) Natural drug resource 3) Tuberculin purpose on TBC: A) As a health promotion B) As a preventive therapy C) As a curative therapy D) As a prophylactic therapy E) As a diagnosis therapy 4) Pharmacognosy, as one of the discipline in drug development, its main aspect was: A) Drug dosage design technology B) Toxicology C) Pharmacodynamic D) Pharmacokinetic E) Natural drug resource 5) Ethnopharmacology, as one of the discipline in drug development, its main aspect was: A) Drug dosage design technology B) Toxicology C) Pharmacodynamic D) Pharmacokinetic E) Natural drug resource

6) Toxicology, as one of the discipline in drug development, its main aspect was: A) Drug safety B) Pharmacotherapy C) Side effect D) Lethal effect E) Adverse effect reaction 7) Drug development stage, healthy human as a sample: A) Screening B) Clinical stage 1 C) Clinical stage 2 D) PMS E) Preclinic 8) Requirement of drug, review and finding on identity until physicochemical aspect: A) Safety B) Efficacy C) Efficiency D) Characteristic E) Evidenced based 9) Preclinical on drug development except: A) As a test on drug binding to receptor, by using isolated cell culture or isolated organ B) Pharmacokinetic, Pharmacodynamic and toxicology test C) Before testing human D) Drug dosage form design test E) In vitro, or in vivo test 10) Birth defect caused by drug toxicity: A) Mutagen B) Genotoxic C) Oncogen D) Teratogen E) Carcinogen

11) Which are the part of 3R Helsinki declaration that minimizing time of experiment procedure on animal: A) Reduce B) Replace C) Refresh D) Refinement E) Rework 12) Enteral route of drug administration: A) Intramuscular B) Sublingual C) Inhalation D) Topical E) Rectal 13) Rectal route of drug administration , except: A) First-pass effect partially avoided B) Absorption unpredictable C) Slow onset of action D) Systemic effect E) Local effect 14) Intravenous route of drug administration, except: A) Complete drug availability B) First-pass effect avoided C) No absorption process D) Easy for personal use E) Bioavailability 15) On bioavailability, the following statement is correct: A) Drug that administered orally has a complete bioavailability B) Bioavailability was influenced by route of administration C) Solutions tend to have lower bioavailability compared with other dosage forms D) Prolonged gastric emptying time will not influence drug absorption E) First pass effect will increase bioavailability

16) Time of administration, food can modify drug absorption through, except: A) Altering gastric emptying time B) Altering GIT secretion C) Competition on drug absorption D) Drug complexation E) Drug metabolism 17) Which of the following dosage form that provide drugs content most easily to be absorbed by GIT membrane: A) Powder B) Capsule C) Tablet D) Solution E) Pill 18) Bioavailability of a drug indicates: A) The amount of drug dissolved in GIT fluid B) The rate of drug dissolved in GIT fluid C) The rate and amount of drug reaching systemic circulation from an administered dose D) The rate of solid dosage form disintegrated into granules E) The rate of granules disaggregated to yield fine particles 19) Which route of drug administration that has fastest onset of action: A) Oral route B) I.V C) I.M. D) Rectal route E) Inhalation 20) Most orally administered drugs are best absorbed by absorbing membrane of: A) Small intestine B) Large intestine C) Stomach D) under tongue E) Hepar

21) The process that contribute to increase bioavailability of drug is: A) Degradation by gastrointestinal enzyme B) Delaying gastric emptying time C) Degradation by gastric acid D) Lowering intestinal motility E) First pass effect 22) Which of the following statements is the advantage of the oral route of administration: A) Food may change the amount of drug absorption in intestinal B) Time of taking medication may influence the absorption C) First pass metabolism may alter the efficacy of drug D) The absorption of drug in intestinal unpredictable E) Convenience in taking medication 23) Liquid drug dosage form for rectal route: A) Solution B) Suspension C) Injectionum D) Emulsion E) Enema 24) Percentage of bioavailability that couldnt reach 100%, except: A) Oral B) Rectal C) Intravena D) Topical E) Inhalation