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Neuro Muscular Blocade in cp

Neuro Muscular Blocade in cp

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Published by praveen

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Published by: praveen on Mar 26, 2009
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06/16/2009

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Neuro-muscular blocade/chemodenervation
Selective denervation of nervesand muscles.Botulin toxin,phenol (3-7%),andalcohol 45-100%
 
Chemodenervation
Phenol, alcohol diffuse few millimetres frominjection siteDenervation with alcohol 3-6 months,Phenol denervation 4-8 months.Effective but side effects of Pain at injection site,Non-selective protein denaturation,Possible permanent muscle fibrosis,Dysaethesias lasting for several weeks.
 
Chemodenervation
Botox for dynamic spasticityPost-operative or post-treatment paincontrol,Focal dystonia,Muscle imbalance producing or contributing to skeletal deformity,As a diagnostic trial,Drooling reduction

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