M. Kaisarul Islam, Lecturer, Department of Pharmacy, Jagannath University, Dhaka-1100, Bangladesh
Mass spectroscopy is a quantitative and qualitative analytical technique bywhich we can measure the molecular mass and formula of a compound andthe record is known as mass spectra.Mass spectra is useful −
To establish the structure of a new compound
To give the exact molecular mass
To give the molecular formula
To indicate the presence of functional group in a compound
The mass spectrometer is designed to perform four basic functions −
To vaporize the compound by increasing volatility.
To generate the ions from the neutral compound in resulting vaporpressure
To separate the ions according to their mass to charge ratio (m/z) ina magnetic field.
To collect the mass and record.Theory:
Molecular ion production:
Mass spectrometer is a device for the production and weighingof ions.
Molecules are subjected to bombardment by a stream of high-energy electrons, converting some of the molecules to ions. Themolecular ions are usually radical cation and some may beradical anion.