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Aplastic Anemia

Aplastic Anemia

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Published by hazelposis

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Published by: hazelposis on Apr 04, 2009
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11/20/2013

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APLASTICANEMIA
HAZEL ARVEE B. POSIS
 
 
The bone marrow (soft tissuewhich is located within thehard outer shell of the bones)is responsible for theproduction of all the types of blood cells. The mature formsof these cells include redblood cells, which carryoxygen throughout the body;white blood cells, which fightinfection; and platelets, whichare involved in clotting. Inaplastic anemia, the basicstructure of the marrowbecomes abnormal, and thosecells responsible for generating blood cells(hematopoietic cells) aregreatly decreased in number or absent. Thesehematopoietic cells arereplaced by large quantities of fat.
 
Is a physiological and anatomical failure of the bone marrow characterizedby a marked decrease or absence of blood-forming elements in the marrowand peripheral pancytopenia (decreased RBCs ,WBCs and platelets ).
A rare and serious blood disorder in which bone marrow stops makingenough new blood cells. aplastic anemia, normal production of all bloodcells—red cells, white cells, and platelets—slows or stops. This is becausethe stem cells have been damaged. The cause of this damage is oftenunknown.Aplastic anemia is caused by damage to stem cells in the bone marrow.Stem cells normally develop into three types of blood cells: red blood cells,white blood cells, and platelets. When stem cells are damaged, they do notgrow into healthy blood cells.

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