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The Hallucinogens

The Hallucinogens

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Published by Projekt E 012
By

A. Hoffer
Formerly
Department Of Public Health
Psychiatric Research
University Hospital
Saskatoon, Canada

H. Osmond
Neuropsychiatric Institute
Princeton, New Jersey

With A Contribution By

T. Weckowicz
Department of Psychiatry
College of Medicine
University of Alberta
Edmonton, Canada

1967
ACADEMIC PRESS New York and London
By

A. Hoffer
Formerly
Department Of Public Health
Psychiatric Research
University Hospital
Saskatoon, Canada

H. Osmond
Neuropsychiatric Institute
Princeton, New Jersey

With A Contribution By

T. Weckowicz
Department of Psychiatry
College of Medicine
University of Alberta
Edmonton, Canada

1967
ACADEMIC PRESS New York and London

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Categories:Types, Research
Published by: Projekt E 012 on Apr 04, 2009
Copyright:Attribution Non-commercial

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08/07/2013

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 THE
HALLUCINOGENS
 A.
 
Hoffer 
H. Osmond 
FORMERLY,
DEPARTMENT OF PUBLIC HEALTH
PSYCHIATRIC RESEARCH
UNIVERSITY HOSPITAL,
SASKATOON, CANADA
 NEUROPSYCHIATRIC INSTITUTE
PRINCETON, NEW JERSEY
 WITH A CONTRIBUTION BY 
T. Weckowicz 
Department of Psychiatry 
College of Medicine 
University of Alberta 
Edmonton, Canada 
1967
ACADEMIC PRESS New York and London
 
COPYRIGHT © 1967, BY ACADEMIC PRESS INC.ALL RIGHTS RESERVEDNO PART OF THIS BOOK MAY BE REPRODUCED IN ANY FORM,BY PHOTOSTAT, MICROFILM, OR ANY OTHER MEANS, WITHOUTWRITTEN PERMISSION FROM THE PUBLISHERS
ACADEMIC PRESS INC.111 Fifth Avenue, New York, New York 10003
United Kingdom Edition published by
ACADEMIC PRESS INC. (LONDON) LTD.
Berkeley Square House, London W.1
LIBRARY
OF CONGRESS CATALOG CARD NUMBER:
66—30086
PRINTED IN THE UNITED STATES OF AMERICA
 
In 1954 we designated mescaline, lysergic acid diethylamide, andadrenochrome as hallucinogens. The only other substances which weclassed as hallucinogens were the active principals from marijuana,harmala alkaloids, and ibogain, not at that time identified chemicallyfor certain. In the past decade so many additional hallucinogens havebeen discovered, studied, and described and so many new publicationshave appeared that this may be the last time it will be possible to give adetailed description of the hallucinogens in a single volume. Withinanother five to ten years each hallucinogen may well require its ownmonograph.The term "hallucinogen" is not completely satisfactory since it overemphasizes the perceptual elements of the response to these drugs, andperceptual changes are often minor; changes in thought and mood aremuch more important. Other terms have been suggested but they, too,have faults. Thus, psychotomimetic has been used as a general description, but these compounds do not necessarily make the subject psychotic.The term delirients seems no better since subjects given these compounds are seldom delirious. Psychedelic, Osmond's word, refers to aparticular kind of drug reaction, as does, of course, psychotomimetic, ordelirium. For these reasons it seems appropriate to continue using theterm hallucinogens for a variety of substances which can produce reactions which may be psychotomimetic, psychedelic, or delirient, depending upon many other factors.Hallucinogens are then chemicals which in nontoxic doses producechanges in perception, in thought, and in mood, but which seldom produce mental confusion, memory loss, or disorientation for person, place,and time. These latter changes are characteristic of organic brain reactions following intoxications with alcohol, anesthetics, and other toxicdrugs.This work has been written for chemists, biochemists, psychologists,sociologists, and research physicians. It cannot, therefore, satisfy eachgroup fully, but we believe that it is sufficiently comprehensive andwell documented so that each group can use it as a springboard forfuture enquiry into these fascinating chemicals.The use of hallucinogens has been described as one of the major advances of this century. There is little doubt that they have had a massive
v
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