SPECIMEN COLLECTIONSPECIMEN COLLECTION FORFORMEASLES VIRUS ISOLATIONMEASLES VIRUS ISOLATION Eshetu LemmaEshetu LemmaBSc (MLT), BA (Econ)BSc (MLT), BA (Econ)
Measles Lab Data ManagerMeasles Lab Data Manager
INTRODUCTIONINTRODUCTION
Virus isolate are extremely important forVirus isolate are extremely important formolecularmolecularepidemiologic surveillanceepidemiologic surveillancetotohelp determine the geographic origin of thehelp determine the geographic origin of thevirus and thevirus and theviral strain circulateviral strain circulate
Isolation of measles virus is notIsolation of measles virus is notrecommended as arecommended as aroutineroutinemethod tomethod todiagnosis measlesdiagnosis measles
Measles virus can be isolated fromMeasles virus can be isolated fromnasopharyngeal aspirate or swab, throatnasopharyngeal aspirate or swab, throatswab, blood, and urineswab, blood, and urine
Clinical specimen for viral isolation shouldClinical specimen for viral isolation shouldbe collected at thebe collected at thesame timesame timeas samplesas samplestaken fortaken forserologicserologictestingtesting
MVMVis more likely to be isolated when the specimens areis more likely to be isolated when the specimens arecollectedcollectedwithin 4 dayswithin 4 daysof rash onsetof rash onset
Collection of specimens for virus isolationCollection of specimens for virus isolationshould not beshould not bedelayeddelayeduntiluntilserologicserologicconfirmation is obtainedconfirmation is obtained
Throat and nasopharyngeal specimens can be collected Throat and nasopharyngeal specimens can be collected– in order of – in order of increasingincreasingvirus yieldvirus yield-by aspiration-by aspiration-by lavage-by lavage-by swabbing of the mucous membranes-by swabbing of the mucous membranes
The sensitivity of The sensitivity of nasal swabsnasal swabsis comparable to that of is comparable to that of nasopharyngeal aspiratesnasopharyngeal aspiratesfor detection measles virusfor detection measles virus
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| Upload Date: | 04/09/2009 |
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