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Alexandria Egypt Sepsis 02-04-09

Alexandria Egypt Sepsis 02-04-09

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Published by: lordoftheweb on Apr 13, 2009
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05/11/2014

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Prof. Christian P. Speer, MD, FRCPEDirector and ChairmanUniversity Children’s Hospital Würzburg, Germany
April 2 - 4, 2009 Alexandria, Egypt
2nd International Neonatology Conference
Neonatal septicemia: Current concepts andthe role of neonatal host defense
 
 
Neonatal Sepsis
Incidence1- 4 Newborns /1000 LB / Year 
Meningitis5 - 25 %
Case fatality~ 25 % (5 - 60%)
 
 
Mortality
1.6 Million Deaths / Year 
1
Infections as cause of death in > 50 % of extremely LBWinfants on autopsy
2
Morbidity
Association between chorioamnionitis and cerebral palsy inmature infants (odds ratio 9.3, CI 2.7-31)
3
Qualitative MRI in extremely LBW infants: Associationbetween non-cystic white mater injury (oligodendroglialspecific injury) and perinatal infection (maternal fever, provenneonatal sepsis at delivery
4
)
Adverse neurodevelopmental outcome in preterm infants withpostnatal sepsis or NEC is mediated by white matter abnormalities on MRI
5
Neonatal Sepsis
1
Vergnano et al, Arch Dis Child Fetal Neonatal Ed 2006;
2
Barton et al, Pediatrics 1999;
3
Grether and Nelson, JAMA, 1997;
4
Inder et al, J Pediatr 2003;
5
Shaw et al, J Pediatr 2008

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