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How to Keep the Stress Hormone Cortisol in Check
How to Keep the Stress Hormone Cortisol in Check
From Aaron Merrill
Endocrine Issues in CriticalEndocrine Issues in CriticalIllnessIllness
Paul Marik, MD, FCCM, FCCPPaul Marik, MD, FCCM, FCCP
Professor of MedicineChief, Div. Pulmonary & CCMThomas Jefferson UniversityPhiladelphia PA
ObjectivesObjectives
Be able to identify the following:
Stress responsePathophysiology of stress hyperglycemiaImmunomodulating properties of glucose and insulinBenefits of tight glycemic controlCortisol physiology and biosynthesisHPA and the stress responseEvaluation of HPA in the critically illAdrenal physiology in sepsisSteroid replacement in sepsis
The Stress ResponseThe Stress Response
Biologic, physical, or psychologic stressors generallyBiologic, physical, or psychologic stressors generallyprecipitate similar response –precipitate similar response –““general adaptation syndrome”general adaptation syndrome”
Selye H. A syndrome produced by diverse nocuousagents. Nature. 1936;138:32.
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Endocrine - FINAL
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| Upload Date: | 04/15/2009 |
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