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Anand Kumar, MDAnand Kumar, MD
Section of Critical Care MedicineSection of Infectious DiseasesUniversity of Manitoba, Winnipeg, CanadaUMDNJ-Robert Wood Johnson Medical SchoolCooper Hospital, NJ
ShockShock
Pathophysiology, Classification, andPathophysiology, Classification, andApproach to ManagementApproach to Management
 
 
ShockShock
Cardiogenic shock- a major component of the the mortalityassociated with cardiovascular disease (the #1 cause of U.S.deaths)Hypovolemic shock- the major contributor to early mortalityfrom trauma (the #1 cause of death in those < 45 years of age)Septic shock- the most common cause of death in AmericanICUs (the 13th leading cause of death overall in US)
 
 
Shock: DefinitionsShock: Definitions
Kumar and Parrillo(1995) - “The state in which profound andwidespread reduction of 
effective
tissue perfusion leads first toreversible, and then if prolonged, to irreversible cellular injury.”
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