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Quiz Hematology Oncology Part 1 of 2

Quiz Hematology Oncology Part 1 of 2

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Published by MedShare
Quiz Hematology Oncology Part 1 of 2
Quiz Hematology Oncology Part 1 of 2

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Published by: MedShare on Apr 15, 2009
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07/16/2013

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Hematology & Oncology Part 1 14Mar2009DO NOT DISTRIBUTE - 1 -
Hematology/Oncology #1 – Embryology
1) Which of the following does NOT function in embryonic hemopoiesis(hemangioblasts as blood cell precursors)?a) Yolk sac b) Liver c) Heartd) Bone Marrowe) Spleen2) The first blood islands appear in the mesoderm surrounding the wall of the yolk sac atapproximately how many weeks of embryonic development?a) 3-weeks b) 9-weeksc) 15-weeksd) 27-weekse) 37-weeks3) What structures could take over hemopoietic function in a child when the usualhematopoietic organs are incapable?a) Heart and lungs b) Kidneys and spleenc) Thymus and kidneysd) Brain and hearte) Spleen and liver f) None (lethal)
Hematology/Oncology #2 – Histology
1) Which of the following is NOT true of the function of blood and plasma?a) Supply of oxygen and nutrients to tissues b) Coagulation and immunologic functionsc) Hydraulic functions with blood volume of about 6.0Ld) Regulation of body pH to about 7.0, neutrale) Messenger functions (hormones) and removal of waste2) Which of the following is NOT true of the structure and function of erythrocytes (red blood cells) and hemoglobin?a) Hemoglobin is comprised of 4 polypeptide chains with a heme b) Red blood cells are biconcave in shape, maintained by membrane proteinsc) Peripheral membrane proteins are on the outer surface of the cell membraned) Integral membrane proteins make up the lipid bilayer e) Red blood cells (RBCs) have a life span of 120 days with most being phagocytized by macrophages in the liver, spleen, and bone marrow3.1) Which of the following is NOT true for a patient with type B- blood (group B andnegative Rh factor)?a) They have a type B surface antigen b) They have anti-A type antibodiesc) They can donate to anyone with type B or AB blood regardless of Rh factor d) They could receive blood from a patient with type O- bloode) They could receive blood from a patient with type O+ blood
 
Hematology & Oncology Part 1 14Mar2009DO NOT DISTRIBUTE - 2 -3.2) What surface antigen is present in people that have type O blood?a) A antigen b) B antigenc) A and B antigend) A or B antigene) No antigen4.1) Which of the following leukocytes is the largest and partially degrades antigens to present the fragments on MHC II for helper CD4 T-cell recognition?a) Neutrophils b) Lymphocytesc) Monocytesd) Eosinophilse) Basophils4.2) Which of the following leukocytes is azurophilic (lysosomes) and is associated withallergic reactions, parasitic infections, and chronic inflammation?a) Neutrophils b) Lymphocytesc) Monocytesd) Eosinophilse) Basophils4.3) Which of the following leukocytes is multi-lobular, azurophilic (bactericidalmyeloperoxidase), is the first to enter damaged areas, activates phagocytes at the site of inflammation, and secrets pyrogenic IL-1?a) Neutrophils b) Lymphocytesc) Monocytesd) Eosinophilse) Basophils4.4) Which of the following leukocytes is azurophilic (lysosomes) and contains heparin,histamine, heparan sulfate, and leukotrienes?a) Neutrophils b) Lymphocytesc) Monocytesd) Eosinophilse) Basophils4.5) Which of the following leukocytes is the main cell of the immune system anddifferentiates into T-cells (helper CD4, cytotoxic CD8), antibody producing B-cells, andnatural killer (NK) cells, which attack certain viruses and tumor cells?a) Neutrophils b) Lymphocytesc) Monocytesd) Eosinophilse) Basophils5.1) Which of the following is identified by the presence of CD34+ surface marker  protein?a) Pleuripotent stem cell (PPSS)
 
Hematology & Oncology Part 1 14Mar2009DO NOT DISTRIBUTE - 3 - b) Colony forming cells (progenitor, CFU)c) Multipotent stem celld) Basophilic erythroblaste) Polychromatophilic erythroblastf) Orthochromatic erythroblast (normoblast)g) Polychromatophilic erythrocyte5.2) Which of the following is under the influence of erythropoietin, IL-3, and IL-4?a) Pleuripotent stem cell (PPSS) b) Colony forming cells (progenitor, CFU)c) Multipotent stem celld) Basophilic erythroblaste) Polychromatophilic erythroblastf) Orthochromatic erythroblast (normoblast)g) Polychromatophilic erythrocyte5.3) Which of the following produces acidophilia (pink) due to hemoglobin staining and basophilia (purple) due to ribosome staining?a) Pleuripotent stem cell (PPSS) b) Colony forming cells (progenitor, CFU)c) Multipotent stem celld) Basophilic erythroblaste) Polychromatophilic erythroblastf) Orthochromatic erythroblast (normoblast)g) Polychromatophilic erythrocyte6) Which of the following has a densely stained nucleus with eosiniphilic (acidophilic)cytoplasm due to large amounts of hemoglobin, is no longer capable of division, andextrudes its nucleus from the cell?a) Pleuripotent stem cell (PPSS) b) Colony forming cells (progenitor, CFU)c) Multipotent stem celld) Basophilic erythroblaste) Polychromatophilic erythroblastf) Orthochromatic erythroblast (normoblast)g) Polychromatophilic erythrocyte7.1) Which of the following is described as becoming more heterochromic, deeplyindented, and forming a kidney bean shaped structure with neutrophils granules toazurophilic granules in a 2-to-1 ratio?a) Myeloblast b) Promyelocytec) Myelocytesd) Metamyelocytese) Band/segmented stage7.2) Which of the following has a euchromic spherical nucleus with agranular cytoplasmthat stains intensely basophilic and is the earliest recognizable neutrophils precursor cellin bone marrow?a) Myeloblast b) Promyelocyte

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